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8 Cards in this Set
- Front
- Back
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Define glomerulonephritis
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renal disease where glomerulus is the primary site of involvement and is inflammatory
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ANS
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acute nephritic syndrome: hematuria, azotemia, HTN
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Disease that produces increased cellularity, subepithelial deposits, hyperplasia, with NO thickening of glomerulus
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Acute proliferative glomerulonephritis
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Pts most susceptible to acute prolif GN.
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children 1-4 weeks after strep throat or impetigo
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Pathophysiology of acute proliferative GN.
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immune complex (Type III) trapping within glomeruli followed by leukocytic infiltration and eventual degradation.
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Serum findings in post-strep acute prolif GN.
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ASO elevation
Complement decreased azotemia |
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Describe crescentic glomerulonephritis.
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crescent shaped proliferation of PARIETAL epithelial cell (not in glomerulus)
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Three classifications of RPGN
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1) Anti-GBM
2) Immune complex mediated disease 3) Pauci-immune glomerulonephritis |
