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31 Cards in this Set
- Front
- Back
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3 emulsifying agents |
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Does w/o or o/w have higher apparent viscosity? |
W/o |
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What affects rheological properties? |
Dispersed phase concentration - increase viscosity Radius of dispersed phase - small size increase viscosity Viscosity of continuous phase - syrups/glycerol but if density too high promote creaming Hydrocolloids- little effect on viscosity of dispersed phase |
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3 measurements of rate of creaming |
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What's a microemulsion |
Smaller dispersed phase droplet size than regular emulsion |
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Use of emulsions |
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What's a suspension? |
State in which particles of a substance are dispersed but not totally dissolved in fluid |
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2 admin routes for suspensions |
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pro and con of suspension |
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Desired features of suspension 3 |
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Which parameters can we control? |
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How does particle size affect suspension |
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3 surface properties of particles |
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3 forces of interaction between colloidal particles |
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Draw an interaction energy-distance curve |
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What happens when particles are coated with hydrated polymer? |
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5 things to consider for suspension excipients |
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Common suspension excipients |
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What do wetting agents do? |
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Deflocculation vs flocculation |
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What's zeta potential? |
Potential difference between surface of solid particle and bulk of liquid |
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How to control flocculation? 3 |
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Disadvantage of flocculated formulation? |
Unsightly and need to be shaken before use |
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What are viscosity agents? |
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How to quantify sedimentation |
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What do electrolytes, surfactants, hydrophilic polymers, preservatives, antioxidants do? |
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Suspension drug release |
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What are extemporaneous suspensions? |
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Why do suspensions and emulsions need excipients? |
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