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20 Cards in this Set

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Enhancement of Solubility/Dissolution of Poorly Water-Soluble Drugs, Part II (Cont.)

Back (Definition)

pH of precipitation

Predicting solubility: General Rules

Enhancement of Solubility/Dissolution of Poorly Water-Soluble Drugs, Part 1

Various approach

Various approach

Partition Phenomena: Significance

It is an important concept for the pharmacists, as several pharmaceutical products involve the use of this principle

Example:


1. Preservation of oil water systems (emulsions)


2. Drug action at non specific sites


3. Drug absorption and distribution

Lipophilicity

A drug molecule should have a balance of lipophilic and hydrophilic properties to adapt to both lipids and aqueous environments in the body.



- Lipophilicity is critical to determine drug behavior in the body.

Permeation through biological membranes


Drug transport


Recognition of drug by receptor


Drug accumulation in tissues

Partition Law and Partition Coefficient

Back (Definition)

Partition Law and Partition Coefficient

Back (Definition)

Partitioning of Non-Electrolytes and Strong Electrolytes

Back (Definition)

Front (Term)

Back (Definition)

Front (Term)

Back (Definition)

Front (Term)

Back (Definition)

Application of Partition Concept in Pharmaceutical Preparations

Back (Definition)

Application of Partition Concept in Pharmaceutical Preparations

Back (Definition)

Disperse Systems: Interfacial Phenomena

Back (Definition)

Disperse Systems: Interfacial Phenomena

Back (Definition)

Surface Tension and Interfacial Tension

Back (Definition)

Spreading and Spreading Coefficient

Back (Definition)

Contact Angle and Wetting

Back (Definition)

Wetting Agents: Surfactants

Back (Definition)