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26 Cards in this Set
- Front
- Back
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CT components
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fibers, ground substance, cells
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Fibroblasts
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secrete ECM materials (including collagen/elastin precursors) and involved in wound healing
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Adipocytes
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Store TG. changes in body fat due to cell size not cell #.
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white fat
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unilocular; single droplet; shock absorber, insulator, energy reserve
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brown fat
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multilocular; multiple droplets; function in thermogenesis.
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brown fat distribution
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neck, pelvis in babies. upper back, neck, collarbone/shoulder areas in adult
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thermogenesis mechanism
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cold temp, NE triggers hydrolysis of lipid droplets in brown fat. FFA metabolized by mitochondria using thermogin protein, which allows H to leak into cell and is dissipated as heat (instead of coupling to ATP production).
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Plasma cells
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derived from B cells in response to specific pathogens; secrete specific immunoglobulins and bind mast cells. located near vessels and in digestive tract
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Mast cells
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derived from hematopoetic stem cells, play role in allergic response. After binding plasma cells, release granules upon re-exposure to that specific pathogen. found in lining of dig/resp tracts, in dermis, near vessels.
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Mast cell granules
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histamine, heparin, chemotactic factors
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histamine
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increases vascular permeabiilty, smooth muscle contraction in bronchioles (asthma)
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heparin
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blocks blood clotting, inactivates histamine
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chemotactic factors
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for neutrophils, esinophils
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Macrophages
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come from bone marrow; phagocytes
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Ground substance
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gives CT its strength/resiliency; regulates exchange of nutrients.
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collagen
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most abundant protein in body
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reticular fibers
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abundant networks in smooth muscle and endoneurium; framework for hematopoetic organs.
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Loose CT
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more cells than fibers; fluid ground substance.
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Dense CT
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more fibers than cells/ground substance. Fibers orientated to resist stress. Regular or irregular
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regular dense CT
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parallel bundles of fibers - tendons, ligs, etc.
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irreg dense CT
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dermis
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adipose tissue
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adipose cells in loose CT. brown fat highly innervated and vascularized
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cartilage
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firm, gel-like ECM, greater than cells/fibers
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hyaline cartilage
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most common type; type II collagen; matrix is surrounded by perichondrium (dense CT with perichondrial fibroblasts that differentiate into chondrocytes) (except articular)
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elastic cartilage
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elastin andtype II collagen fibers. chondrocytes lie between bundles of elastin fibers (which appear dark)
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fibrocartilage
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present in transition areas near bone, muscle. chondrocytes are in linear arrays. type I collagen.
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