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28 Cards in this Set

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ondansetron (Zofran) pregnancy class

B

ondansetron (Zofran) class

antiemetic




antivertigo




serotonin 5-HT3 receptor antagonist

ondansetron (Zofran) MOA

blocks serotonin in the CTZ and peripherally on vagal X nerve terminals in GI tract to nv

ondansetron (Zofran) important notes

may prolong QTI

ondansetron (Zofran) route

SIVP 2mg/min


IO


IM


PO ODT

ondansetron (Zofran) onset

30 to 60s

ondansetron (Zofran) duration

4 hours

ondansetron (Zofran) dosage

4mg

ondansetron (Zofran) adverse effects

headache


anxiety


fever, chills




hypoxia


fatigue


somnolence (sleepiness)




abd pain


constipation


urine retention


diarrhea

carvedilol (Coreg) MOA

selectively blocks α and β receptors


⇨ vasodilation


⇨ ⬇PVR




⊖ inotrope


⊖ chronotrope


⇨ ⬇CO


⇨ prevents tachycardia

carvedilol (Coreg) pregnancy category

D

carvedilol (Coreg) dosage

20 to 80mg daily




or




double pt regular dose

carvedilol (Coreg) class

adr class II β blocker


aht


aa

carvedilol (Coreg) indications

HTN


CHF


stable angina


L ventricular failure after AMI

carvedilol (Coreg) adverse effects

dizziness


hypotension


bradycardia




dyspnea


bronchospasm


HB


fatigue

carvedilol (Coreg) heads up

⬆ bradycardia with: digoxin (Lanoxin)


calcium channel blockers

carvedilol (Coreg) contraindications

pulmonary edema not caused by heart failure


bronchospasm




2° and 3° HB


bradycardia




cardiogenic shock

carvedilol (Coreg) ROD

PO


onset 1 hour


duration 12 hours

norepinephrine (Levophed) class

sympathomimetic


catecholamine


vasopressor

norepinephrine (Levophed) pregnancy category

pregnancy safety not established

norepinephrine (Levophed) indications

sympathomimetic


catecholamine


vasopressor

norepinephrine (Levophed) indications

cardiogenic shock


neurogenic shock


shock with SBP<70

norepinephrine (Levophed) MOA

acts directly on α receptors


⇨ vasoconstriction ⇨ ⬆BP


⬆CO


⬆coronary perfusion

hypovolemia contraindications



severe hypoxia


vfib


tachycardia


hypovolemia

norepinephrine (Levophed) heads up

tissue necrosis


⬆ mod




hx cardiac


HTN


PVD




α & β blockers antagonize


MAOIs & TCAs potentiate




light sensitive

norepinephrine (Levophed) ROD

IVPB


onset 1 to 3 min


duration 1 minute after discontinued

norepinephrine (Levophed) dosage

0.5 to 1mcg/min titrated




max 30mcg




mix 4mg in 250ml NS or D5W

norepinephrine (Levophed) adverse effects

headache


nv


dizziness




dyspnea




bradycardia/tachycardia


palpitations


angina


ectopy




weakness