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8 Cards in this Set
- Front
- Back
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Types of Immunity
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Active and Passive
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Active 2 types
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natural-survive a disease
artificial-vaccine, toxoid |
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Passive 2 types
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natural-mother to fetus
artificial-antitoxin, antivenom, immune globulins |
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3 Types of Vaccines
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Killed microbes-need boosters
Attenuated-need titers Toxoids-q 10yrs |
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Vaccine
-Prototype- |
-hepatiis B (Engerix-B, Recombivax HB)
-MOA: provide active immunity c multiple injections -PU: people at risk for HepB -AE: pain and inflam at injection site, fever, fatigue -CI: sick, diarrhe, vomiting, pyrexia, prego, diabetes, heart disease, renal failure |
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Immunostimulant
-Prototype- |
interferon a-2a (Roferon-A)
MOA: stimulates/enhances immune sys. to remove antigens; suppresses cancer cell growth PU: remove hairy-cell leukemia, chronic HepC or malignant melanoma, HepB; AIDS-related AE: flu-like syndrome in 50% of people, headache, nausea, vomiting, diarrhea, anorexia, depression, suicidal idea., immunosuppression, hepatotoxicity, neurotoxicity CI: Renal and liver disease, pregnancy |
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Immunosuppresant
-Prototype- |
cyclosporine (Neoral, Sandimmune)
MOA: inhibit helper t-cells PU: transplant recipients AE: 75% of people experience decreased urine flow, infections, tremor, HTN, increased hepatice enzymes and cancer CI: leukemia, metasatic cancer, infection, renal or liver disease, Preg |
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4 Types of Immunosuppressants
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-Glucocorticoids-inhibit inflam
-Antimetabolites-inhibit lympho replication -Antibodies-fights human t-cell -Calcineurin inhibitors-disrupt cell fxn. |
