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46 Cards in this Set
- Front
- Back
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Atropine-like side effects
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Tricyclics
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Coronary vasospasm
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Cocaine, sumatriptan
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Cutaneous flushing
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Niacin, Ca2+ channel blockers, adenosine, vancomycin
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Dilated cardiomyopathy
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Doxorubicin (Adriamycin), Daunorubicin
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Torsade des pointes
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Class III (sotalol), class IA (quinidine) antiarrhythmics, cisapride
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Agranulocytosis
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Clozapine, carbamazepine, colchicine, propylthiouracil, methimazole
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Aplastic anemia
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Chloramphenicol, benzene, NSAIDs, propylthiouracil, methimazole
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Direct Coombs-positive hemolytic anemia
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Methyldopa
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Gray baby syndrome
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Chloramphenicol
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Hemolysis in G6PD-deficient patients
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hemolysis IS PAIN: Isoniazid (INH), Sulfonamides, Primaquine, Aspirin, Ibuprofen, Nitrofurantoin
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Thrombotic complications
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OCPs
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Cough
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ACE inhibitors
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Pulmonary fibrosis
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Bleomycin, busulfan, amiodarone
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Acute cholestatic hepatitis
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Macrolides
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Focal to massive hepatic necrosis
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Halothane, valproic acid, acetaminophen, Amanita phalloides
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Hepatitis
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Izoniazid
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Pseudomembranous colitis
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Clindamycin, ampicillin
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Adrenocortical insufficiency
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Glucocorticoid withdrawal (hypothalamic-pituitary-adrenal axis suppression)
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Gynecomastia
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Some Drug Create Awesome Knockers: Spironolactone, Digitalis, Cimetidine, chronic Alcohol use, estrogens, Ketoconazole
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Hot flashes
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Tamoxifen, clomiphene
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Gingival hyperplasia
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Phenytoin
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Gout
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Furosemide, thiazides
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Osteoporosis
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Corticosteroids, heparin
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Photosensitivity
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Sulfonamides, Amiodarone, Tetracycline
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SLE-like syndrome
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Hydralazine, Izoniacid, Procainamide, Phenytoin
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Tendonitis, tendon rupture, and cartilage damage in kids
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Fluoroquinolones
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Fanconi's syndrome
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Expired tetracycline
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Interstitial nephritis
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Methicillin, NSAIDs
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Hemorrhagic cystitis
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Cyclophosphamide, ifosfamide (prevent by coadministrating with mesna)
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Cinchonism
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Quinidine, quinine
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Diabetes insipidus
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Lithium, demeclocycline
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Seizures
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Bupropion, imipenem/cilastatin
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Tardive dyskinesia
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Antipsychotics
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Disulfiram-like reaction
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Metonidazole, certain cephalosporins, procarbazine, 1st generation sulfonylureas
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GI distress, dizziness, headache
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Echinacea
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CNS and cardiovascular stimulation, arrhythmias, stroke, seizures
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Ephedra
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GI distress, mouth ulcers, antiplatelet actions
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Feverfew
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GI distress, anxiety, insomnia, headache, antiplatelet actions
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Gingko
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GI distress, sedation, ataxia, hepatotoxicity, phototoxicity, dermatotoxicity
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Kava
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Loose stools
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Milk thistle
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GI distress, decreased libido, hypertension
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Saw palmetto
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GI distress and phototoxicity, serotonin syndrome with SSRIs, induces p-450 system
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St. John's wort
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Androgenization (premenopausal women), estrogenic effects (postmenopausal), feminization (young men)
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Dehydroepiandrosterone
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Sedation, suppress midcycle LH, hypoprolactinemia
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Melatonin
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Which drugs are P-450 inducers?
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Queen Barb take Phen-phen and Refuses Greasy Carb Shakes: Quinidine (can induce and inhibit), Barbituates, Phenytoin, Rifampin, Griseofulvin, Carbamazepine, St. John's wor
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Which drugs are P-450 inhibitors?
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Inhibitors Stop Cyber-Kids from Eating Grapefruit: Isoniazid, Sulfonamides, Cimetidine, Ketoconazole, Erythromycin, Grapefruit juice (also Quinidine which can also induce)
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