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38 Cards in this Set
- Front
- Back
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3 Names of Drugs
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Chemical
Generic Trade |
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Chemical
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chemical constitution of the drug
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Generic
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formularies/drug book
Not capitalized |
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Trade
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Registered
capitalized |
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Complete and Correct Medication Order
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Patient Name
Date order is written Name of Medication Dosage Route Signature of prescriber |
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Pharmaceutics
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study of how various dosage "forms" influence pharmacokinetic and pharmacodynamics
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Pharmcokinetics
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study of what the BODY does to the DRUG
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Pharmcodynamics
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study of what the DRUG does to the BODY
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ENTERAL
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absorbed in the GI Tract (oral or rectal)
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PARENTERAL
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Injectable form
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TOPICAL
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Applied to the skin or inhaled
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4 Phases of Pharmacokinetics
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ADME
Absorption Distribution Metabolism Excretion |
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What are we especially interested in during the pharmacokinetic phases?
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Onset- when does the drug start to work
Peak- when the drug is most effective Duration-how long does the drug effect last |
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Bioavailibility
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Express the "quantity" extent of drug absorption
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Firstpass Effect
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refers only to drugs absorbed from the GI tract. Drugs absorbed from the GI tract must 1st pass via portal circulation through the liver to reach systemic circulation. This pass results in some drug being metabolized/diverted/ excreted by the liver.
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Protein-bond
"bound" |
Inactive
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Protein-bond
"unbound" |
active and can be distributed to extravascular tissue
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Biotranformation
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Metabolism
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Which organ is most responsible for biotransformation?
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Liver
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Which is the primary organ for excretion?
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Kidney
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Half-life
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time it takes for one half of the original amount of the drug taken to be removed from the body
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Additive Effect
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two drugs with similar effect given together so each can be given in smaller doses
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Synergistic Effect
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effect greater than that of each given individually
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Antagonistic Effect
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effect is less than that drug would achieve separately
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Age
Pediatrics |
Birth-13months
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Age
Geriatrics |
post 65 years
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what pregnancy drug categories are safe for pregnant woman
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A and B
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Pregnancy Category C
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Adverse effect in animal fetus reported
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Pregnancy Category D
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Possible human fetal risk reported
consider benefit to risk |
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Pregnancy Category X
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Fetal abnormalities
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Neonate
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less than 1 month old
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Infant
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1 month to 1 year
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Child
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1 year to 12 years
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Poly pharmacy
2 or less |
6% chance of drug interaction
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Poly pharmacy
3-5 |
50% chance of drug interaction
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Poly pharmacy
8 or more |
100 percent of drug interaction
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1938 Revision of Food and Drug Act
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as established mandatory testing for safety prior to marketing!
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5 Rights
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Right Drug
Right Dose Right Time Right Route Right Patient Right Documentation |
