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26 Cards in this Set
- Front
- Back
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adrenergics, xanthines, anticholinergics,
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bronchodilators
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corticosteroids, leukotriene modifiers, mast cell stabilzers
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anti-inflammatory
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stimutlates beta 2 receptors in the smooth muscle (bronchi and bronchioles)
other: stimulate beta 1 receptors to increase heart rate and contractility |
bronchdilators
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tachycardia, arrythmias, palpitations, restlessness, agitation, insomnia
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bronchodilators AE
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used to prevent and treat bronchconstriction
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albuterol
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increases cyclic amp(adenosine monophophate) by inhibiting enzyme that metablozes amp, bronchodilation occurs decreases vascular permeablilty increases ability of cilia to clear mucus and strengthen contractions of diaphragm
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xanthines prototype is theophylline
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stimulation of cns tachycardia, palpitations, arrhythmias, restlessness, agitation, insomnia, nausea and vommiting, convulsions with toxic levels, monitor serum drug levels
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xanthines: prototype theophyline
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blocks action of acetylcholine in bronchial smooth muscle (bronchodilate)
used with adrenergics like albuterol not for acute bronchospasm |
antocholinergics: atrovent (ipratropium)
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cough, nervousness, gi upset, headache, dizziness
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atrovent: adverse effects
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decrease inflammation, mucous secretion, airway edema and reactivity increase number of B-2 so bronchodilate
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corticosteroids
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used in combo with bronchodilators or mast cell stabilizers taken on a reg basis
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corticosteroids: beclovent
(beclomethasone) |
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fungal mouth infections, hoarseness, cough, throat irritation
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beclovent : AE
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reduces bronchoconstriction and inflammation used for prophylaxis and chronic tx.
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leukotriene modifiers
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headache nausea diarrhea infection increased live enzymes monitor lover function studies
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leukotriene modifiers AE
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allows decreased doses of bronchodilators and corticosteroids
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mast cell stabilizer: comolyn
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arrythymias, hypotension, chest pain, restlessness, dizziness, convulsions, cns deprssion, anorexia, nausea and vomitting
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comolyn AE
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inhibit vascular permeability, inhibit edema formation, inhibit bronchoconstriction, inhibit puritis
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antihistamines- h1 receptor antagonists
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allergic rhinitis, urticaria and puritis secondary to anaphylaxis, allergic cpnjunctivis, drug allergies, contact dermititus, hives, also used fr promotion of sleep and decreased dizziness.
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antihistamines: indications
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relief symptomes of rhinitis, decrease nausea and vomiting, decrease dizziness (when used for motion sickness), drowsiness (when used for sleep)
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antihistamine: therapeutic effects
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cns depression, drowsiness, sedatation, anticholinergic effects, dry mouth, urinary retention, constipation, blurred vision
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antihistamines : AE
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causes sedation (somtimes restlessness in children), seizures, dryness, nausea and vomitting
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1st generation: benadryl (AE)
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peripheral H1 receptors so causes less cns depression and does not cross bbb, drowsiness, dry mouth, fatigue, headache, GI upset
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zyrtec (certerizine), and Allegra and Claritin (AE) 2nd generation
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antihistamines, nasal decongestants, analgesics, antitussives, expectorants
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cold remedies
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Normalize metabolism
Increase energy, heart rate, respiratory rate, alertness, appetite, temperature Constipation is decreased Effects are as early as 2-3 days after therapy |
synthroid therapeutic effects
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Therapeutic effects: slower and more normal activity, slower HR, speech, decreased nervousness, able to sleep, wt. gain
Adverse effects: Hypothyroidism, agranulocytosis, fever, sore throat, headache, dizziness, drowsiness, decreased taste |
Propylthioracil
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Inhibits the production of conversion of T3 and T4
Therapeutic effects in several days Large doses are given until normal thyroid activity is reached (6-8 weeks) then smaller maintenance dose for 1 year Gradually discontinue over weeks/months |
Propylthioracil
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