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38 Cards in this Set
- Front
- Back
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inhibit synthesis of bacterial cell walls in Gm- and Gm+ mostly Gm+
AE: nephrotoxicty increased dose hypersensitivty, diarrhea, neurotoxicity inrcreased dose, gi irritation. |
penicillin
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penicillin G (pfzerpan)
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penicillin prototype
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streptococcal infections, strept throat, RF (endocraditis)
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penicillin indications for use
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resistant bacteria- require penicillinase- resistant penicillins
inhibitor added to extend drug activity: ex: ampicillin/ sublacatam (unsyn) probenecid with penicillins increase drug levels ampicillin Gm- and Gm+ |
penicillin misc
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ask client about allergy to PCN
empty stoamch report severe diarrhea do not take with acid drinks Oj and Crandberry juice |
penicillin teachings
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inhibit synthesis of bacterial cell walls G- mostly
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cephlasporins
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cefaclor (ceclor)
cefazolin (kefzol, ancef) |
cephlasproins protatype
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surgical prophalaxiz respiratory infection skin tissues joints uti blood infection
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cephlasprins indications of use
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1st 2nd 3rd generations
cross sensitivty with pcn |
cephlasprins misc
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with food or milk
report sever diarrhea |
cephlasproins
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prevent protein synthesis Gm- bacteria
-pseudomonas -klebsiella -e.coli -serratia -proteus -enterobacter AE: nephrotoxicity with increase dose in elderly ototoxicty with increase dose in elderly neurotoxicity |
aminoglycosides
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gentamicin (garamycin)
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aminoglycosides
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serious systemic infections TB (streptomycin) before bowl surgery (neomycin)
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aminoglycosides
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im,iv
careful regulation of dose to avoid toxicity. loading dose and maintenance dose. monitor level with peak and trough. single dose to prevent nephrotoxcity need for levels avoid dehydration |
aminoglycosides
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interfer with dna Gm-
AE: hypersensitivty, photosensitivy |
fluoroquinolines
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ciproflaxcin ( cipro)
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fluoroquinolines
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infections of respiratory gi gu (utis)
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fluoroquinolines
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most given orally not for <18 not for prego or lactating
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fluorquinolines
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avoid sunlight
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fluoroquinolines
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inhibit microbial protein synthesis Gm+ some Gm-
AE: photosensitivity suferinfection |
tetracyclines
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tetracycline (achromycin)
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tetracylines
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not systemic infections
acne uncommon infections = cholera, typhus, RMSF, also urethral, cervical, rectal (chlamydia) |
tetracyclines
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gm+ strep and staph are resistent
used in Gm+ only when client has allergy to PCN contraindicated: renal failure, prego, <8 yr |
tetracyclines
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avoid sunlight
with food to avoid N&S not with dairy product antacid or iron (take 2 hours before and after ) oral care |
tetracyclines
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halt multiplication (bacteriostatic) Gm+ and Gm-
AE: photosensitivity hypersensitivity |
sulfanomides
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sulfadiazine combination agent
bactrim- most common |
sulfanomides
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common use utis
topical sulfanomides (silvadene) used for burn sepsis |
sulfanomides
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avoid aspirin, ibprofen- increase toxicity - displace drug. contrainficated: with allergy to salicylates
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sulfanomides
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empty stomach (before or after meals) avoid the sunlight. 2-3 qts water a day
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sulfanomides
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analgesic action.
indicated for treatmenr of pain, urgency and frequency associated with utis |
urinary agents
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furadantin, pyridium
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urinary agnts
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specific use:utis
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urinary agents
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expect discolored urine with pyridium- turns urine orange-red
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urinary agents
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inhibit microbial protein syntheses Gm+ cocci (strep&staph)
AE: (erythromycin)-hepatotoxicity- exc iv-phelbitis AE: misc drugs: vancomycin: nephrotoxicity, ototoxicity cindamycin: severe diarrhea |
macrolides
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erythromycin (E-mycin)
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macrolides
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E-mycin: respiratory infections, soft tissue. (used for RF, STD's if allergey to PCN)
vancomycin: severe infections |
macrolides
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excreted by live- caution wth liver impairment
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macrolides
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suspension: empty stomach- evenly spaced rount the clock
tablets: anytime |
macrolides
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