Pathology Ch. 11 Study Guide 2

Front 1

Microcytic

Back 1

•RBC are small

Front 2

Hypochromatic

Back 2

•RBC is pale (Lack Iron)

Front 3

Hyperspleenism

Back 3

•Consumes more than the normal amount of WBC, RBC, or platelets.

•Is associated with enlarged spleen.

Front 4

Spleenomegaly

Back 4

•Enlarged spleen

Front 5

Aplastic Anemia

Back 5

•Primary bone marrow failure

-It is the primary failure of marrow elements red cells, white cells, and megakarocytes

Front 6

Macrocytic

Back 6

•RBC are large

Front 7

Ferritin

Back 7

•Is an iron-protein complex found in the bone marrow, liver, spleen, and skeletal muscle.

Front 8

Transferrin

Back 8

•Iron is transporred from one place to another bound to a special protein made by the liver.

Front 9

Polycythemia vera

Back 9

•Is a chronic myeloproliferative disorder in which malignant proliferation of primitive bone marrow red cell precursors predominates.

Front 10

Leukopenia

Back 10

•Low WBC, usually granulocytes

Front 11

Neutropenia

Back 11

•A decrease of granulocyte number, especially neutrophils

°Due to hyperspleenism, sepsis, autoimmune disease.

°If severe: Agranulocytosis - chemotherapy

-Susceptible to bacterial & fungal infection

Front 12

Lymphopenia

Back 12

•Low numbers of lymphocytes

-Usually associated with Immune deficiency diseases.

Front 13

Agranulocytosis

Back 13

•Severe neutropenia

Front 14

Leukemia

Back 14

•Is a malignant proliferation of white cells, either Lymphoid cells or myeloid cells, in which the malignant cells appear in the peripheral blood.

Front 15

Lymphoma

Back 15

•A malignant neoplasm of lymphocytes in lymph nodes and organs that grow as nodular masses.

-However, no malignant cells are detectable in blood.

Front 16

Epstein-Barr Virus

Back 16

•The agent of Infectious mononucleosis; also associated with some malignancies, especially lymphoma.

Front 17

Waldenstrom

Back 17

•A cross between multiple myeloma and small cell lymphocytic lymphoma.

Front 18

Multiple Myeloma

Back 18

•Is a malignant proliferation of plasma cells

Front 19

Acute Lymphocytic Leukemia

Back 19

•An uncommon malignant proliferation of immature lymphocytes, usually B cells, that most often occurs in children and young adults.

Front 20

Chronic Lymphocytic Leukemia

Back 20

•Is a malignant proliferation of B cells that accounts for about a third of all leukemias and is indistinguishable from small cell lymphocytic lymphoma.

Front 21

Actute Leukemia

Back 21

•When the malignant cells are immature (Blasts)

-It is aggressive and runs a short course.

Front 22

Chronic Leukemia

Back 22

•When the malignant cells are mature.

-Which is less aggressive and runs a longer course.

Front 23

Myeloidysplasia

Back 23

•Is a group of bone marrow stem cell proliferations characterized by ineffective RBC production and a tendency to evolve into acute myelocytic leukemia.