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41 Cards in this Set
- Front
- Back
Acute Inflammation
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limited in area and duration
characterized by the cardinal signs of inflammation |
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Cardinal signs of inflammation
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Redness
Heat Swelling Pain Loss of function |
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resolution
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reversal of the inflammatory process with return to normal
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repair
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healing of the damaged area
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microcirculation
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delivery of fresh blood to the smallest blood vessels, present in the vasculature embedded within organ tissues
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vasoconstriction
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immediate constriction of the microcirculation comprising the arterioles, capillaries, and venules. constriction is very brief lasting several minutes or less
serves the purpose of controlling bleeding, especially in small injuries |
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chemical mediators
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substances that start the inflammatory process
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vasodilation
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increase in diameter
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hyperemia
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increase in blood, more blood
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permeable
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having pores or openings that permit liquids or gases to pass through
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plasma fluid
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fluid in vessels that flows out and into the area where injury occurred.
necessary to clear the area of dead or injured cells and any foreign material that entered |
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exudate
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fluid that came from the blood vessels into the injured tissue
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serous exudate
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thin and clear exudate with few cells (for example blisters)
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vascular stasis
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slowing of the blood through the vessels in the affected area
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leukocytes
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white blood cells
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endothelium
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lining of the vessels
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margination
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movement toward the endothelial cells
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adhesion or pavementing
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process of white blood cells sticking to the enothelium
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transmigration or emigration
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when the white blood cells are firmly attached to endothelial cells and they squeeze through the gaps between the cells in the vessle wall
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chemotaxis
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The characteristic movement or orientation of an organism or cell along a chemical concentration gradient
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opsonization
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event that enables the leukocytes to destroy and remove resistant organizms
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opsonins
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chemical substances that prepare resistant organisms for destruction
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immunoglobulins
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a type of opsonin
natural antibodies produced by the immune system |
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phagocytosis
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when leukocytes ingest and digest foreign matter
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granlocytes
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one class of leukocytes
include polymorphonuclear neutrophils, eosinophils, and basophils |
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agranulocytes
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leukocytes that include lymphocytes and monocytes
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mast cell
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not a leukocyte, but does exhibit some of the same properties of a basophil
very important to the immune system |
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polymorphonuclear neutrophil (PMN)
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most active granulocyte in the inflammatory process
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motile phagocytes
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phagocyte that can move independently within the tissues and carry out the process of phagocytosis of whatever material they are sent to eliminate
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basophil
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play a role in inflammation related to allergic reactions
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eosinophil
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plays a role in inflammation related to allergic reactions. also active in fighting of parasitic infections.
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monocyte
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a type of white blood cell
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macrophage
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white blood cells within tissues, produced by the division of monocytes
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lymphocyte
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leukocytes found in the lymph system
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histamine
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an important chemical mediator
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lipopolysaccharide (LPS)
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component of all gram negative bacterial cell walls
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serotonin
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preformed chemical mediatory that is released from platelets in response to platelet-activating factor
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platelet-activating factor (PAF)
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derived from the cellmembranes of neutrophils, eosinophils, basophils, mast cells, monocytes, platelets, and endothelial cells
Causes the aggregation of platelets and release of serotonin from the platelets |
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prostaglandins
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cause vasodilation, increase vascular permeability, and increased feelkings of pain
type of synthezised chemical mediator synthezided by all types of leukocytes |
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leukotrienes
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a type of synthezised chemical mediator
increase vascular permeability and act as chemotactic agents to bring inflammatory cells into an area synthezided by all types of leukocytes and mast cells |
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test
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test
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