Nmj Ch 28

Front 1

depolarizing neuro muscular junction

Back 1

succinylcholine

Front 2

Area on the muscle cell membrane where ACh reacts with a specific receptor site to cause stimulation of the muscle in response to nerve activity

Back 2

acetylcholine receptor site

Front 3

stimulation of a muscle cell causing it to contract with no allowance for reploarization and restimulation of the muscle characterized by contraction then paralysis

Back 3

Depolarizing NMJ

Front 4

The synapse between a nerve and a muscle cell

Back 4

neuromuscular junction

Front 5

reaction to some NMJ drugs in susceptible individuals characterized by extreme muscle rigitiy seve hyperpyrexia acidosis and in some cases death

Back 5

malignant hyperthermia

Front 6

No stimulation or depolarization of the muscle cell prevents depolarization and stumulation by blocking the effects of ACh

Back 6

Nondepolarizing NMJ blocker

Front 7

Lack of muscle function

Back 7

paralysis

Front 8

Functional unit of a muscle cell composed of actin and myosin molecules arranged in layers to give the unit a striped or striated appearance

Back 8

SARCOMERE

Front 9

THEORY EXPLAINING MUSCLE CONTACTION AS A REACTION OF ACTIN AND MYOSIN MOLECULES WHEN THEY ARE FREED TO REACT BY THE INACTIVATION OF TROPONIN AFTER CALCIUM IS ALLOWED TO ENTER THE CELL DURING DEPOLARIZATION

Back 9

SLIDING FILAMENT THEORY

Front 10

CHEMICAL USED TO COMMUNICATE BETWEEN NERVES AND MUSCLES

Back 10

ACh

Front 11

a FAMILY OF ENZYMES THAT CATALYZE THE HYDROLYSIS OF THE NEUROTRANSMITTER ACh

Back 11

CHOLINESTERASE

Front 12

NAME NON DEPOLARIZING NEUROMUSCULAR JUNCTION

Back 12

ATRACURIUM
CISATRACURIUM
PANCURONIUM
ROCURONIUM
VECURONIUM

Front 13

inhibits nerve actvity and is important in preventing over excitability or stimulation such as seizure activity.

Back 13

Gamma Aminobutyruc acid (GABA)

Front 14

non depolarizing act as antagonist to ACh at the NMJ and precent Depolarizing (ACTION) of muscle cells

Back 14

Non depolarizing (REST)

Front 15

Act as and ACh agonist causing stimulation of the muscle cel and preventing it from repolarizing

Back 15

Depolarizing (ACTION)

Front 16

A patient receives pancuronium. The nurse would expect the patient to feel the effects of the drug for which duration?

Back 16

120 to 180 minutes

Front 17

After teaching a group of students about NJM blockers, the instructor determines that the teaching was successful when the students identify which of the following as an example of a nondepolarizing NMJ blocker? Select all that apply.

Back 17

• Vecuronium
• Pancuronium
• Cisatracurium

Front 18

A patient that has a history of glaucoma is to receive a NMJ blocker. Which agent would the nurse identify as being most problematic for this patient?

Back 18

Succinylcholine

Front 19

When describing the sliding filament theory, which of the following would an instructor include?

Back 19

Calcium combines with tropinin

Front 20

When nondepolarizing NMJ blockers are given, histamine is also released causing wheezing and bronchospasm. t/f

Back 20

True

Front 21

A 71-year-old patient with a history of depression will be receiving vecuronium to prevent trauma during electroconvulsive therapy. Prior to the procedure, the care team must assess the patient's

Back 21

renal and hepatic status.

Front 22

A patient will be undergoing surgery, during which the anesthesiologist plans to administer vecuronium. The nurse will recognize that the administration of this drug creates a need for

Back 22

mechanical ventilation

Front 23

When assessing a patient who has received a nondepolarizing NMJ blocker, the nurse determines that the patient is experiencing excessive effects of the drug. Which of the following would the nurse expect to be used?

Back 23

Cholinesterase inhibitor

Front 24

Which neuromuscular blocking agent would a nurse expect to have the shortest duration of action?

Back 24

Succinylcholine

Front 25

Which of the following would a nurse expect to administer to a patient who is experiencing muscle pain related to the use of succinylcholine?

Back 25

Aspirin

Front 26

only depolarizing blocking drug with a half life of 6 min reaction time of 30-60 seconds

Back 26

succinylcholine

Front 27

used in adjunct to anethetics during sugery relaxes smooth mnuscle helps facility mechanical intubation prevents resistance to the resporator used to realign broken bnes used to faviityate electroconvulsive therapy reducests the intensity of spasm in undiced seizures

Back 27

Neuromuscular junction blocking agents

Front 28

contraindicated in Alaskan eskimoes due to lower cholinesterase level than any other ethnicity

Back 28

Neuromuscular junction blocking agents

Front 29

calcium channel blockers _____NMJ blocking agents

Back 29

potentiate

Front 30

3 MAIN USES FOR NEUROMUSCULAR BLOCKLING DRUGS THAT RELAX SKELTAL MUSCLES BY DISRUPTING THE TRANSMISSION OF NERVE IMPULSES AT THE MOTOR END PLATE. THE BRANCHING THE HAVE 3 MAJOR CLINICAL USES?

Back 30

TO RELAX SKELTAL MUSCLES DURING SURGERY 2 TO REDUCE THE INTENSITY OF MUSCLE SPASMS IN DRUG OR ELECTRICALLY INDUCED SEIZURES 3 MANAGE PATIENTS FOR ARE FIGHTING THE USE OF A VENTILATOR TO HELP WITH BREATHING.

Front 31

2 MAJOR CLASSIFICATIONS

Back 31

1 NONDEPOLARIZING
BLOCKING DRUGS
2DEPOLARIZING BLOCKING DRUG

Front 32

NAME DEPOLARIZING BLOCKING DRUG

Back 32

SUCCINYCHOLINE - DRUG OF CHOICE WHEN SHORT TERM MUSCLE RELAXATION IS NEEDED

Front 33

5 N DEPOLARIZING DRUG

Back 33

ATRACURIUM
CISTRACURIUM
PANCURONIUM
VECURONIUM