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34 Cards in this Set

  • Front
  • Back

Apraxia

A condition where people can perform only simple movements. Happens after lesion of PMA (premotor area) or SMA (supplementary motor area)

Basal ganglia

collections of neurons in the base of forebrain. Includes caudate nucleus, putamen, globus pallidus, subthalamus, substantia nigra

Caudate

Nucleus beside lateral ventricles

What makes up the striatum?

Caudate nucleus and putamen

cerebellar lesion cause

ataxia (uncoordinated movements) and intention tremors

nucleus ambiguous location

In the medullary reticular formation


Controls lower motor neurons that innervates larynx and pharynx

Parkinsons disease is associated with what structure?

Substantia nigra

The motor loop through basal ganglia pathway is

cortex (m1) to striatum to globus pallidus to thalamus to cortex

bradykinesia

slow movements

Akinesia

difficulty initiating movements

Symptoms of parkinsons disease

bradykinesia, akinesia, rigidity, tremor at rest, dopamine depletion in substantia nigra, caudate and putamen

Huntingtons disease symptoms

Degeneration of caudate, putamen, globus pallidus


Hyperkinesia and dyskinesia


Chorea: spontaneous and purposeless movements

Cerebellum function

coordinate movements


receives input from pons

hemiballism

unilateral flinging hyperkinesia

Motor loop through cerebellum

Cortex -> pons -> cerebellum-> thalamus -> cortex

Where are upper motor neurons located?

From primary motor cortex down the spinal cord.

What do upper motor neurons control?

Somatic (voluntary) movements

Where are lower motor neurons located?

Spinal efferents in ventral horn, include alpha motor neurons

What is a motor unit?

Alpha motor neuron and all the fibers it innervates

What is a motor neuron pool?

All alpha motor neurons that innervate a single muscle

What is ALS? (Amyelotrophic Lateral Sclerosis)

A degenerative disease of the alpha motor neurons

What neurons does stretching activate?

1a afferents, alpha efferents shut off 1a efferents, gamma efferents reactivate 1a afferents

What is the reverse myotactic reflex?

Too much strain inhibits lower motor neuron, preventing overload, allows fine movements

What gauges strain on a muscle?

Golgi tendon organ and 1b afferent nerves

Alpha efferents activate what

1b afferents

What is Lou Gehrig’s Disease?

Loss of voluntary movement (walking, speaking, swallowing) due to loss of lower motor neurons.

What are some causes of Lou Gehrig’s Disease?

Genetics: damage from oxygen (bad glia)


Excitotoxicity from glutamate

What are the physical properties of a muscle determined by?

Neurons

What are the 3 inputs to alpha motor neurons?

Input from spinal interneurons, muscle spindles, upper motor neurons in the brain.

What are two types of stretch receptors?

Muscle spindles and 1a afferents

What is the myotactic, monosynaptic reflex?

When the muscle contracts when it is stretched

What are 1a afferents typically involved in?

Reciprocal inhibition

Alpha motor neurons innervate what fibers?

Extrafusal fibers of the motor unit

Gamma motor neurons innervate what fibers?

Intrafusal fibers of the muscle spindle