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10 Cards in this Set
- Front
- Back
What is salicylism?
|
chronic aspirin toxicity
headache, dizziness, tinnitus, hearing loss, drowsiness, ketosis, hypokalemia |
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Why shouldn't aspirin be given to a child with a viral infection?
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can cause Reye's syndrome
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What is diflunisal and how is it different from aspirin?
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a COX inhibitor
has no antipyretic effect |
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Name two cox-2 inibitors
use (2) |
celecoxib
rofecoxib RA and OA |
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what is different about cox-2
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they spare the GI lining that is associated with NSAIDs
|
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What is better about ibuprofen?
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has greater analgesic potency than aspirin or acetaminophen
|
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Why is Naproxen useful?
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has alinger half-life than other NSAIDs
|
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Acetaminophen actions
|
anti-pyretic
analgesic (no antiinflammatory or platelet inhibition) |
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Acetaminophen use
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aspirin contraindicated (especially in kids with viral infection or pts on aticoag or gout)
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Acetaminophen toxicity (3)
antidote |
hepatic necrosis
acute tubular necrosis hypoglycemic coma |