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4 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Monobactams |
Example of this monobactam is Aztreonam |
The beta lactam ring of monobactams are not fused to another ring |
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Act against gram negative organisms like Enterobacteriacea P. aeruginosa
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It lacks activity against gram positive and anaerobes. |
Is resistant to beta lactamasesExcept ESBLs. |
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Pk of monobactams ...aztreonam |
Administration :IV or IM Can accumulate in patients with renal failure |
Relatively non toxic tho it may cause phlebitis, skin rash |
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Aztreonam may be safer alternate for treating patients who are allergic to other penicillin, cephalosporins or carbapenems. |
Best choice of all beta lactams in case of severity of allergic reactions |
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