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28 Cards in this Set
- Front
- Back
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What is the morphology of Francisella tularensis
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fastidious gram negative aerobic coccobacillus
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why are there so many different disease presentations with Francisella tularensis ?
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it depends on the method of getting the bug
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how can you get Francisella tularensis ?
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bug bites
direct animal contact inhalation of aerosol** ingesting contaminated meat animal bite |
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Is there person to person transmission of Francisella tularensis?
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no there is not
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what is the most common type of Francisella tularensis infection?
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ulceroglandular tularemia
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What kind of cells does ulceroglandular Francisella tularensis infect?
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macrophages, causes painful papule and then ulcer at about 96 hours
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what does Francisella tularensis inhibit inside macrophages?
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inhibits pahgosome-lysosome fusion
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what happens regionally with ulceroglandular Francisella tularensis ?
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severe lymphadenopahy in regional nodes, resembles bubonic plauge
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how dangerous is pneumonic tularemia?
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this has a high morality rate of up to 30%
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what does pneumonic tularemia do?
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this causes multiple necrotizing graunlomas that destroy alveolar septa
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how do you treat tularemia?
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streptomycin or gentamicin
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what does tularemia serology cross react with?
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brucella*
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How many species of brucella are there?
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four, depending on what the host organism in
cattle dogs swine goats and sheep |
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what is the morphology of brucella?
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small G-, coccobacillus
obilagte aerobe catalase, oxidase, urease positive |
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what two stats is brucella most common?
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texas and california
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whos is most at risk for brucella?
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drinking unpasturized milk
people in contact with infected animals lab techs |
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what is the presentation of brucella infection?
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fever- undulant fever* wild flucuations*
malaise, weight loss, arthralgias, non productive cough |
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what happens with chronic brucella infection?
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abscesses and granulomas are seen
many different symptoms |
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what must you do before sending in a brucella sample?
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lab notification is required
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how do you treat brucella?
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doxycycline with rifampin
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what is the morphology of bartonella?
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small gram negative aerobic bacilli
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what is the host for bartonella henselae?
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cats- causes cat scratch fever
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How do you transmit bartonella in general?
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bite by arthropod
or cat bite/scratch |
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where is bartonella bacilliformis common to?
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brazil
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what types of cells does bartonella bacilliformis affect?
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RBC's causes Oroya fever when they breakdown
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What is the chronic form of bartonella bacilliformis?
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verruga- red/purple skin lesions in crops that appear/persistant for months to years
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what are the symptoms of bartonella henselae?
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severe lymphatic swellic
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what causes bacillary angiomatosis in immunocompomised people in the US?
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usually bartonella henselae
but can be bartonella quintana |
