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37 Cards in this Set
- Front
- Back
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How recent is Rubeola?
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this is a new human virus
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When is it best to get rubeola?
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as a child
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How do people get atypical measles?
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people who got an inactivated vaccine, and then are exposed to a mild wild type virus
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How long is the rubeola prodrome stage?
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this is 1-12 days post infection
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What are the three C's of rubeola prodrome?
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Coryza, cough, conjunctivits
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What are the diagnostic spots of measles?
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Koplik spots on buccal mucosa, which appear before rash eruption
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How long does it take for rubeola to create a rash?
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the rash does not appear until 3-4 days after prodrome initiates
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Is quarantine effective for rubeola?
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no it is not, as by the time the pt has the rash they have been infected for some time
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What is the pattern of rubeola rash development?
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begins below ears, spreads over forehead to face, neck, trunk, and extremities in three days
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What protein was involved in creating atypical measles?
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the viral F protein in the vaccine
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What was the presentation of atypical measles?
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this looks like RMSF, palm/sole rash without face rash
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what are the most common complications of measles?
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bacterial infections like pneumonia
Diarrhea CNS acute encephalitis |
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What is SSPE?
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subacute sclerosing panencephalitis, this is a sequela of measles infection. Slow acting virus in the brain- always fatal
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How can measles affect the immune system?
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this can damage/attenuate the immune response. causing exacerbation of CMI response
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Where does viral replication of rubeola occur?
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in the host cytoplasm
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Why is it rare for rubeola to infect infants?
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because maternal immunity often lasts for the first 6 months or so
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What age group usually gets rubeola?
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this is a disease of children, usually by age 10
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When does measles usually peak?
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this peaks with drier weather in spring
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How does measles enter the body?
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this enters via the respiratory tract
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When are people contagious with rubeola?
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during the prodrome till 4-5 days after the rash erupts
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What type of vaccine is MMR-II?
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this is a live attenuated virus
(so not ok for immunocompromised people) |
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What is the MMR dosing schedule?
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12-15 months old for first dose
4-6 years for second dose |
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Will atypical measles ever be an answer on the test?**
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NO
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can MMR be given during pregnancy?
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no it cannot
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Does MMR contain mercury?
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no it does not have dimersol
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What vitamin may help reduce measles mortality?
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vitamin A
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How does measles usually spread around the world?
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via air travel (this is how the world is going to end apparently)
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What is first disease?
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measles
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What is second disease?
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scarlet fever
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What is third disease?
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german measles
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How long is the incubation period of rubella?
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14-21 day incubation period
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How does the rash appear in rubella?
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this starts of the face and moves downward
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What is the key epidemiological difference between rubeola (measles) and rubella (german measles)
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rubella is a weak, and ineffective at affecting everyone in the room
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Who is most affected by Rubella?
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neo nates who get it from their mothers during pregnancy
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What are the manifestations of congenital rubella syndrome?
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cardiac defects- pulmonary artery stenosis, PDA
eye defects- cataracts, glaucoma hearing loss CNS involvement |
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When is german measles the worst to get?
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during the first trimester of pregnancy
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What is the pre vaccine method of preventing rubella?
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rubella party! infecting all the kids
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