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41 Cards in this Set
- Front
- Back
What is the invasive agent of toxoplasma?
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sporozoites
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what are the two ways to get toxoplasma?
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oocyst- cats
troph- eating lamb |
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what happens with toxoplasma infection in susceptible peoples?
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cysts in muscle and brain tissue
chorioretinitis |
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what are the signs of congenital toxoplasmosis?
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hydrocephalus
mental retardation cerebral calcification chorioretinitis |
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what trimester is the worst to get toxoplasma?
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1st trimester
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What type of cat most commonly has toxoplasma?
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feral cats
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what is the diagnostic stage of toxoplasma?
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tachyzoite and bradyzoite
ELISA serum |
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What is the vector for African trypansomiasis?
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tetese fly
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What is important about African trypansomiasis and its glycoproteins?
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this bug will often switch its surface antigens and thus evade the immune system
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what happens at the site of innoculation with African trypansomiasis?
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big chancre sore
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What are the classical manifestations of African trypansomiasis?
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lymphadenitis
fever somnolences mental dullness tremors of tongue paralysis |
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where is African trypansomiasis located?
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central and west africa
in HUMID forests** |
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what are the reservoirs for African trypansomiasis?
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human and pig
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what is the diagnostic stage of African trypansomiasis?
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trypomastigote in blood (the flat worm like parasite stage)
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What is the acute form of sleeping sickness?
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trypanosoma rhodesiense
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what are the signs of trypanosoma rhodesiense ?
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sore/chancer
fever lymphadenitis parasetemia |
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How fast does trypanosoma rhodesiense kill?
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quickly before the sleepiness occurs
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where is trypanosoma rhodesiense located?
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central and east africa
dry savanna woodlands |
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what is the vector for trypanosoma rhodesiense ?
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tsetse flies
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What is tyrpanosoma cruzi?
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chagas disease
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Where is tyrpanosoma cruzi common?
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poor latin america
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How do you get infected with tyrpanosoma cruzi?
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kissing bug bites you, then poops the infective stage into the wound
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what stage of tyrpanosoma cruzi is in the blood?
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trypomastigote
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what stage of tyrpanosoma cruzi is in the tissues?
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amastigote
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what is the acute phase of tyrpanosoma cruzi infection?
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fever, fatigue, myalgia, large spleen, swollen glands
Romana's sign- swelling of eyelid trypanosomes in blood |
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What are the chronic complications of tyrpanosoma cruzi?
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cardiac!!
failure, arrest, ruputre, and cardiomyopathy |
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How does tyrpanosoma cruzi affect the GI nervous system?
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this destroys the nervous tissue in the GI, causing megacolon and megaesophagus
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how is tyrpanosoma cruzi transmitted?
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arboborne (bugs), sexual, transfusion, transplacental
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What is the infective stage of leishmania?
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promastigote
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What is the intracelular form of leishmaniasis?
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amastigote
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What bug causes leishmania?
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sand fly
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What are the signs of leishmaniasis
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cutaneous ulcers develp at bite site
these ulcers are primary signs |
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What cell does leishmaniasis infect?
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macrophages
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What does Leishmania braziliensis cause?
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this causes nasty ulcers and cartilage destruction
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can you have recurrence with Leishmania braziliensis?
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yes
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does Leishmania braziliensis heal on its own?
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yes it does
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what causes mucocutaneous leishmania?
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Leishmania braziliensis
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What happens with recurrent Leishmania braziliensis?
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advanced scarring
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what are the signs of Leishmania donovani?
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this attacks the internal organs
hepatosplenomegaly fever |
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What is Post Kala-Azar?
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this is recurrent Leishmania braziliensis due to Inadequate treatment
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what is the treatment for Leishmaniasis?
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stibogluconate sodium
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