Microbiology Drug Mode Of Action

Front 1

Which microorganisms do Penicillins, Cephalosporins, & Bacitracin target? What is the mode of action?

Back 1

Bacteria; block cell wall synthesis

Front 2

Which microorganisms are Penicillins, Cephalosporins, & Bacitracin used against? What is the mode of action?

Back 2

bacteria; block cell wall synthesis

Front 3

Which microorganisms are Aminoglycosides used against? What is the mode of action?

Back 3

bacteria; bind to the A-site of the 30s subunit of bacterial ribosomes, blocking protein synthesis

Front 4

Which microorganisms are Tetracyclines used against? What is the mode of action?

Back 4

bacteria; binds to ribosomes, blocking protein synthesis

Front 5

Which microorganisms are Macrolides used against, besides fungi? What is the mode of action?

Back 5

bacteria (and fungi); in bacteria it blocks protein synthesis by binding to the 50s subunit of the ribosome

Front 6

Which microorganisms is Chloramphenicol used against? What is the mode of action?

Back 6

bacteria; blocks peptide bond formation & protein synthesis

Front 7

Which microorganisms are Fluoroquinolones used against? What is the mode of action?

Back 7

bacteria; inhibit the bacterial DNA gyrase enzyme which is necessary for DNA replication

Front 8

Which microorganisms are Rifampin used against? What is the mode of action?

Back 8

bacteria; blocks the action of RNA polymerase, preventing transcription

Front 9

Which microorganisms are sulfonamides used against? What is the mode of action?

Back 9

bacteria; acts by blocking folic acid synthesis and in turn, DNA & RNA synthesis

Front 10

Which microorganisms are Trimethoprim used against? What is the mode of action?

Back 10

bacteria; inhibits a second enzymatic step in the synthesis of folic acid

Front 11

Which microorganisms are Macrolides & Azoles used against, besides bacteria? What is the mode of action?

Back 11

Fungi; binds to fungal membranes and causes a loss of selective permeability

Front 12

Which microorganisms are Flucytosine used against? What is the mode of action?

Back 12

Fungi; act on fungal DNA & RNA synthesis, stopping cell reproduction

Front 13

Which microorganisms are Quinines used against? What is the mode of action?

Back 13

Protozoa; acts on the nutrition of the malaria parasite causing a buildup of toxic wastes in the parasites cells

Front 14

Which microorganisms is Metronidazole used against? What is the mode of action?

Back 14

Protozoa; targets anaerobic cells causing a buildup of toxic free radicals

Front 15

Which microorganisms are Bendazoles used against? What is the mode of action?

Back 15

Helminths; inhibit the function of the microtubules, which interferes with their glucose utilization and disables them

Front 16

Which microorganisms are Piperazines used against? What is the mode of action?

Back 16

Helminths; paralyze the muscles of intestinal roundworms

Front 17

Which microorganisms are Niclosamides used against? What is the mode of action?

Back 17

Helminths; destroys the scolex and the proglottids of tapeworms, thereby loosening the worm's holdfast

Front 18

Which microorganisms is Diethylcarbamide used against? What is the mode of action?

Back 18

Helminths; kills larval forms

Front 19

Which microorganisms is Ivermectin used against? What is the mode of action?

Back 19

Helminths; targets the worm's nerve cell transmission causing the worm to be expelled

Front 20

Which microorganisms is Amantadine used against? What is the mode of action?

Back 20

viruses; function by blocking the hemagglutinin receptors, preventing fusion of the virus with cell membranes

Front 21

Which microorganisms are Cyclovirs used against? What is the mode of action?

Back 21

viruses; mimic the structure of nucleotides and compete for sites on replicating DNA causing an interruption of the viral life cycle

Front 22

Which microorganisms is Azidothymidine used against? What is the mode of action?

Back 22

viruses; interfere with the reverse transcriptase enzyme