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11 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Cephalosporins are less effective than Pencillins in disrupting cell wall synthesis
T/F? |
False
cephalosporins are more resistantant to beta lactamase than penicillin |
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Name the 3 Antimetabolite AB
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Sulfonamide
Isoniazid Trimethoprime These prevent PABA incorporation into folic acid |
SIT
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Rifamycins inhibits DNA synthesis
T/F? |
False, Rifamycins a macrolide (like azithromycin ,clarinthromycin and erythromycin) inhibit RNA synthesis by binding the 50 S subunit
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Which drug disrupts the cell membrane of bacteria?
What is the contra-indication? |
Polymyxin B,
It is used as a last result bc it is nephrotoxic |
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Which antibiotic binds in the presence of Ca++ to release K+(from the bacteria)?
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Daptomycin
works against Gram+ it is a cyclic lipoprotein |
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What was Daptomycin derived from?
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Streptomyces Reseosporus
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Fosfomycin
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Inhibits NAM synthesis
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D-cycloserine
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Inhibits D-ala D-ala
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Bacitracin
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Inhibits dephosphorulation of NAG carrier phospholipid. (Normally the dephosph. is what drives the cell wall synthesis forward)
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Inhibits Nam-Nag-Pep elongation
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Vancomycin
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Inhibits transpeptidase function and thereofre peptidoglycan (PEP) crosslinking (alanine to glycine)
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b-lactamase
penicillin cephalosporin Carbapenem and Monobactam |
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