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46 Cards in this Set
- Front
- Back
Microscopy
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discovery of the very small
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First used a microscope
published observations in Micrographia, 1665 |
Robert Hooke
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Skilled in grinding lenses
Described "animolocules" in specimen of lake water |
anton von leeuwenhoek
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Life can spontaneously arise from non-living sources
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Abiogenesis
Spontaneous Generation |
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Suggests maggots come from eggs, not rotting meat
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Anton von Leeuwenhoek
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When flies are prevented from landing on meat, maggots were not produced
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Redi
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Experiments with boiled broth
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Spallanzani
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Discredited spontaneous generation
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Louis Pasteur
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Understanding disease transmission
study of the source, cause and mode of transmission of disease |
epidemiology
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determined the source of blood poisoning in women during childbirth
hand-washing with chlorinated water |
Ignaz semmelweis
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Determined source of cholera transmission in London
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John snow
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Exposure to disease creates immunity
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variolation
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Developed vaccination
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edward jenner
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Proposed Germ Theory in 1862
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Louis Pasteur
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Used phenol during surgery to kill infections
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Joseph Lister
Antisepsis |
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Formalized standards to identify germs with infectious disease
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robert koch
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first golden age of Microbiology
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1854-1914
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Adding gelatin to broth enabled the creation of colonies in petri dishes
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Pure Culture techniques
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Koch Postulates
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same organism present in every case
Cultured organism inject healthy animal culture organism from sich animal |
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Focused on infection and immunity
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Pasteur lab
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anthrax and cholera experiments
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pasteur lab
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principles of vaccination
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pasteur lab
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isolation, culture & identification
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koch lab
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isolated tubercle, typhoid and diphtheria bacilli
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koch lab
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determined water is key to tuberculosis transmission
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koch lab
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Current areas of study
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Disease
Environmental processes understanding common life processes |
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Shapes & Number of prokaryotes
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Spherical
Rods Spiral over 10 million |
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Domains of Prokaryotes
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bacteria
archaea |
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Known viruses
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over 3600
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Virus replication / composition
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DNA or RNA with protein coat
replicate using cell's machinery |
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Known fungi
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over 70,000
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Fungi live where
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in food source
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Fungi cause
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both disease and cures
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protista
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Both free-living and symbiotic
can cause disease in humans |
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second golden age of microbiology
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1943-1970
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Model System bacteria
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Escherichia Coli
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discovered that bacteria can mutate to generate resistance to viral infection
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salvador luria & max dulbruck
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Early work on DNA as genetic material done by
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Oswald Avery
Colin MacLeod Maclyn McCarthy Alfred Hershey Martha Chase |
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Chemical to cure syphilis
Who, when, what? |
Paul erlich
1910 Salvarsan |
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Mold that kills other bacteria
Name, created, discovered by, when |
Penicillium
Penicillin Alexander Fleming 1929 |
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Third Golden age of Microbiology
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Now
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Annual death toll from infectious disease
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15 million
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T/F
Pathogens can cause more than one disease |
TRUE
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T/F
Pathogens can become resistant to antimicrobials |
TRUE
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T/F
Pathogens can be used for bioterrorism |
TRUE
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T/F
Pathogens can be engineered into Zombie Virus |
UNKNOWN
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