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22 Cards in this Set
- Front
- Back
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mobile DNA |
segments of FNA that can move from one site to another within other DNA molecules |
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transposition |
pieces of DNA move, insert different sites in genome |
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transposable elements |
-transposons -insertion sequences |
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Inverted repeat |
IR on each side of transposase gene |
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wild-type |
strains possess the typical or representative characteristics of a species |
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forward mutation |
mutation from a wild type to mutant form |
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reversion mutation |
second mutation that restores the wild type genotype |
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morphological mutation |
change in colonial or cellular morphology |
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lethal mutation |
mutation that kills |
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conditional mutation |
mutation expressed only under certain conditions |
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transitions mutation |
purine to purine spon |
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transversion mutation |
purine to pyrimidine spon |
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proofreading |
can remove mismatched base immediately after it is added |
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induced mutation |
mutation after mutagen exposure, chemical or physical agents, damage or alter DNA |
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UV light |
induced -generates thymine dimers |
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base analogs |
induced -resemble bases, causes mismatch -5 bromouracil -T analog pairs with G |
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intercalating agents |
induced -ethidium bromide |
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missense |
singe base substitution, changes codon for one AA into codon for another |
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nonsense |
converts sense codon to stop |
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frameshift |
insertion or deletion of one or two base pairs in coding region of gene |
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"Light" repair=photoreactivation |
light activated photlyase -binds, cuts thymine dimer |
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"dark" repair- nucleotide excision repair |
UvrABC endonuclease removes section of damages nucleotides -DNA pol I fills, ligase joins |
