Micro Test 3

Front 1

STD and eye infections

Back 1

Chlamydia trachomatis

Front 2

Walking Pneumonia

Back 2

Chlamydophila pneumoniae

Front 3

Parrot fever- resp infections

Back 3

Chlamydophila psittaci

Front 4

Rocky Mountain spotted fever

Back 4

Rickettsia rickettsii

Front 5

Murine typhus

Back 5

Rickettsia typhi

Front 6

Monocytic/Granulocytic infections

Back 6

Ehrlichia/Anaplasma

Front 7

Q fever- pneumonia

Back 7

Coxiella burnetii

Front 8

Respiratory tract mycoplasma

Back 8

M. pneumoniae

Front 9

GU, PID

Back 9

Mycoplasma genitalium

Front 10

GU

Back 10

Ureplasma urealyticum

Front 11

transmissible spongiform encephalopathies via infective particle

Back 11

Prion

Front 12

Obligate intracellular bacteria requiring host ATP- Energy Parasite

Back 12

Chlamydia

Front 13

OIB that resists drying and proteolytic degradation

Back 13

Chlamydia

Front 14

Non-motile bacteria that stains G(-) that causes STD and eye infections

Back 14

Chlamydia trachomatis

Front 15

Life cycle w/i epithelial cytoplasmic vacuoles

Back 15

Chlamydia

Front 16

Has infective elementary bodies that transform into reticulate bodies

Back 16

Chlamydia

Front 17

Has reticulate bodies in endocytic vesicles that undergo binary fission to make EBs

Back 17

Chlamydia

Front 18

Group A- mammalian parasites (person to person)
Chlamydia

Back 18

C. trachomatis
C. pneumonia

Front 19

Group B- bird parasites (birds to man)
Chlamydia

Back 19

C. psittaci

Front 20

Pathology of this microbe is caused by damage due to granuloma formation, lymph blockage, fallopian tube blockage, and corneal scarring

Back 20

Chlamydia

Front 21

Grows on McCoy human cells

Back 21

Chlamydia

Front 22

NAAT, mAbs, complement fixation

Back 22

Chlamydia

Front 23

Intra-cytoplasmic inclusions around the infected cell nucleus

Back 23

Chlamydia

Front 24

Most frequently reported STI bacterial disease in USA

Back 24

Chlamydia

Front 25

"silent" or "stealth pathogens" --> asymptomatic

Back 25

Chlamydia

Front 26

Species or serovar-specific Ab produced to outer membrane proteins

Back 26

Chlamydia

Front 27

15 serotypes or serovars/biovars

Back 27

Chlamydia

Front 28

Lymphogranuloma venereum-STD
Asia, Africa, S. America
L1-L3

Back 28

Chlamydia trachomatis

Front 29

Ocular trachoma
A-C

Back 29

Chlamydia trachomatis

Front 30

Inclusion conjnctivitis (adult and newborn) GU, NGU, pneumonia of the newborn
D-K

Back 30

Chlamydia trachomatis

Front 31

Pneumonia
1 serovar

Back 31

Chlamydophila pneumonia

Front 32

EBs enter host cells via receptor mediated phago in a vacuole- phagosome

Back 32

Chlamydia

Front 33

Chemokines produced by infective epithelial cells triggers influx of PMNs, NK cells, lymphocytes and MO, IL-17 resulting in chronic inflammation and epithelial cell necrosis

Back 33

Chlamydia trachomatis

Front 34

Ornithosis

Back 34

Chlamydophila psittacii

Front 35

Highly infectious disease of birds (turkey USA), rarely transmitted to man

Back 35

Chlamydophila psittacii

Front 36

Inhalation of dried bird feces causes chills, high fever, persistent unproductive cough

Back 36

Chlamydophila psittacii

Front 37

Spread by respiratory droplets and responsible for ~20% community acquired pneumonia

Back 37

Chlamydophila pneumoniae

Front 38

Mild atypical pneumonia (bronchitis and pharyngitis)

Back 38

Chlamydophila pneumoniae

Front 39

~50% of PID

Back 39

C. trachomatis

Front 40

CD4 T helper CMI responses favor resolution of infection and protective immunity

Back 40

Chlamydia

Front 41

Obligate intracellular pleomorphic bacteria
G(-) small, binary fission

Back 41

Rickettsia

Front 42

Highly fastidious vector borne disesase- ticks, mites, fleas, lice

Back 42

Rickettsia

Front 43

zoonoses infections-arthropod

Back 43

Rickettsia

Front 44

Replicate in the cytosol of endothelium and spread to adjacent cells via long cellular projections

Back 44

Rickettsia

Front 45

Replicate only in phagolysosomes

Back 45

Coxiella

Front 46

replicate in leucocytes

Back 46

Erlichia/Anaplasma

Front 47

hyperplasia of endothelial cells and localized thrombus formation leading to obstruction of blood flow

Back 47

Rickettsia

Front 48

Angitis accounts for petechial rash

Back 48

Rickettsia

Front 49

PCR, CF with serologic increase in Ab titer

Back 49

Rickettsia

Front 50

Weil-Felix rx based on shared cell wall Ag with other bacteria-- Proteus

Back 50

Rickettsia

Front 51

Possess RNA and DNA and produce limited ATP

Back 51

Rickettsia

Front 52

Cell walls not susceptible to lysozyme

Back 52

Rickettsia

Front 53

mobilize host cell actin fibrils to facilitate exit

Back 53

Rickettsia

Front 54

Transmitted by ticks

Back 54

R. rickettsii
Ehrlichia & Anaplasma

Front 55

Transmitted by louse

Back 55

R. prowazeki

Front 56

Transmitted by flea

Back 56

R. typhi

Front 57

Transmitted by aerosols via domestic livestock (Sheep) containing dust, animal urine, feces, placental tissues

Back 57

Coxiella burnetii

Front 58

Unpasteurized milk or cheese

Back 58

Coxiella burnetii

Front 59

Rash is the result of RBC leakage of dialated blood vessels. Petechiae develop centripetally

Back 59

RMSF

Front 60

Rash begins on the extremities (palms and soles) and rapidly covers body

Back 60

RMSF

Front 61

fever, rash, tick bite

Back 61

RMSF

Front 62

Pinpoint hemorrhages lead to encephalitis, pneumonitis, cardiac arrhythmia, nausea, and vomiting. Can affect liver

Back 62

RMSF

Front 63

Rash on trunk. Fever stupor, delirium

Back 63

Epidemic typhus (R. prowazekii)

Front 64

acute fever, myalgia, severe leucopenia and thrombocytopenia. Rash is rare

Back 64

Ehrlichiosis & Anaplasmosis

Front 65

2 major Ag- capsular and cell wall

Back 65

Rickettsia

Front 66

Sulfonamides are contraindicated

Back 66

Rickettsia

Front 67

Bacteria lacking peptidoglycan cell walls and require sterols to grow

Back 67

Mycoplasma & Ureaplasma

Front 68

Facultative intracellular growth

Back 68

Mycoplasma & Ureaplasma

Front 69

Transmitted by respiratory droplets and sexual activity

Back 69

Mycoplasma & Ureaplasma

Front 70

Adherence to respiratory epithelium leads to ciliostasis and cell destruction due to H202 and superoxide anion

Back 70

Mycoplasma & Ureaplasma

Front 71

PCR, DNA probes, ELISA, slow growth media

Back 71

Mycoplasma & Ureaplasma

Front 72

"fried egg" colonies

Back 72

Mycoplasma & Ureaplasma

Front 73

No Beta-lactams due to lack of cell wall

Back 73

Mycoplasma & Ureaplasma

Front 74

smallest free-living bacteria capable of passage through filters

Back 74

Mycoplasma

Front 75

Multiply by binary fission slowly in sterol media

Back 75

Mycoplasma & Ureaplasma

Front 76

Adherence proteins are major virulence factor

Back 76

Mycoplasma & Ureaplasma

Front 77

Adhesin binds sialic acid residues on host

Back 77

Mycoplasma & Ureaplasma

Front 78

colonization of respiratory tract leads to dry cough
5-15 y/o

Back 78

M. pneumoniae

Front 79

Capable of super Ag that stimulate polyclonal T cell activation and cytokine release

Back 79

Mycoplasma

Front 80

cold agglutinins, IgM

Back 80

M. pneumonia

Front 81

Mycoplasmas sexually transmitted

Back 81

M. genitalium
M. hominis
Ureaplasma urealyticum

Front 82

Tracheobronchitis
Persistent non-productive hacking cough after incubated 2-3 weeks

Back 82

M. pneumoniae

Front 83

Community caused aquired pneumonia
walking pneumonia

Back 83

M. pneumoniae

Front 84

Associated with NGU in men

Back 84

M. genitalium
M. hominis

Front 85

Cervicitis, endometritis, PID in women

Back 85

M. genitalium
M. hominis

Front 86

Urethritis in men

Back 86

Ureaplasma

Front 87

tip organelles

Back 87

Mycoplasma

Front 88

Associated with chronic fatigue syndrome, fibromyalgia sx, gulf war sx, rheumatoid arthritis

Back 88

Mycoplasma

Front 89

Can grow in tissue fluids and inside any living tissue w/o killing the cells

Back 89

Mycoplasma

Front 90

Resistant to heat and disinfectants but sucesptible to bleach

Back 90

Prions

Front 91

Long incubation with no host immunologic response that is rapidly progressive and fatal

Back 91

Prions

Front 92

Transmissible via digestion of infected brain products, grafts, and heredity

Back 92

Prions

Front 93

CJD, FFI, Kuru
human forms

Back 93

Prions

Front 94

BSE & Scrapie
animal form

Back 94

Prions

Front 95

Transmitted by cannibalism

Back 95

Kuru

Front 96

"mad cow disease", trasmitted to humans by eating foods contaminated with brain (sweetbread), spinal cord or digestive tract

Back 96

Bovine spongiform encephalopathy

Front 97

Human form of BSE

Back 97

vCJD

Front 98

Propagate by transmitting a misfolded protein state; induces properly folded protein to convert

Back 98

Prions

Front 99

Resistance to conventional sterilization and capacity to bind surfaces of metal and plastic w/o losing infectivity

Back 99

Prions

Front 100

Deposited into environment through dead animals, urine, saliva, body fluids

Back 100

Prions

Front 101

Neurodegenerative dz by aggregating extracellularly w/i CNS to form plaques (amyloid)--> holes in tuessue

Back 101

Prions

Front 102

Elevated levels of 14-3-3 proteins in CSF

Back 102

Prions

Front 103

PRNP gene for making PrP(c) on chr20

Back 103

Prions

Front 104

Codon 178 replaces asparagine w/ aspartic acid

Back 104

FFI and CJD