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16 Cards in this Set

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Salmonella

•Facultative Anaerobic


•Motile


•Non-spores


•No Ferment Lactose


•Oxidase Negative
•Urease


•S. Bongori
•S. Enterica

Salmonella found in?

Reptiles, birds, mammals

Salmonella: Salmonellosis


(uncooked eggs, chicken)

•Diarrhea, fever, inflammation, vomiting


•Lead to osteomyelitis in sickle cell patients


•Leads to reactive arthritis
•Self limiting, run course


•Paratyphoid fever, Typhoid fever

Salmonella

•Paratyphoid fever, Typhoid fever


•Salmonella enterica, subsp. enterica, serovar Typhi


•Macrophages harbour bacteria in asymptomatic carriers


•High fevers, red spots, weakness, altered mental status


•Fluoroquinolone,Cephalosporin (3rd generation, gram -)


Oral rehydration therapy


•Vaccine

Shigella

•Facultative Anaerobe


•Non-motile


•Non-spores forming


•Shiga toxin


•Invasion direct damage to intestinal epithelial cells
•Protein synthesis
•S. Dysenteriae, S. Flexneri, S. Sonnei

Shigella: Shigellosis

•Shiga toxin - highly specific to primates


•Bacteria replicate intracellularly in intestinal epithelial cells
•Bloody,mucoid diarrhea, nausea, vomiting


•Ampicillin, Cephalosporin, Fluoroquinolone, Oral rehydration, Trimethoprim-sulfamethoxazole


•No Vaccine

Yersinia

•Facultative Anaerobe


•Causes plaque
•Y. Enterocolitica, Y. Pestis

Yersinia pestis

•Non-motile


•No Lactose Fermentation


•No Urease


•Bubonic plague


•Pneumonic plague


•Septicemic plague


•Aminoglycoside, Fluoroquinolone, Tetracycline

Yersinia pestis: Bubonic plague

•Infect lymphatic system


•Colonize & reproduce in lymph nodes


•Y.pestis resist destruction within phagocytes


•Painful enlargement of lymph nodes, hemorrhage & become necrotic

Yersinia pestis: Pneumonic plague

•Inhalation of bacteria


•Extremely virulent


•Respiratory failure & shock rapidly ture

Yersinia pestis: Septicemic plague

•Disseminated infection


•Endotoxin leads to DIC (Disseminated Intravascular Coagulation)

Pasteurellaceae

•Actinobacillus


•Aggregatibacter


•Haemophilus


•Pasteurella

Haemophilus

•Aerobic or facultative anaerobic (lives in O2 but live w/out it)
•H. Aegyptius


•H. Ducreyi


•H. Influenzae


•H. Parainfluenzae

Haemophilus Ducreyi (STD)

•Causes chancroid


•Painful lymphadenopathy
•Painful ulcers, exudative, soft borders


•Ulcers resemble chancre seen in syphilis
•Cephalosporin, Macrolide
•Resistant to Aminoglycosides, Penicillin, Sulfonamides, Tetracycline

Haemophilus Influenzae

•Mistaken for cause influenza


•Vaccine for Encapsulated (Hib) (proteins on capsule)


•NO Vaccine for Unencapsulated strains (NTHi)


•Conjunctivitis


•Epiglottitis


•Meningitis


•Otitis media


•Pneumonia


•Sinusitis


•Ampicillin, Cephalosporin, Fluoroquinolone

Haemophilus Parainfluenzae

•Conjunctivitis


•Otitis media


•Peritonitis


•Infective endocarditis (not treated lead to HEART failure)


•Ampicillin with Aminoglycoside, Fluoroquinolone