Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
11 Cards in this Set
- Front
- Back
|
Does urea contribute to the osmolality?
|
Yes, but not the effective osmolality
|
|
|
What osmolality does the body like to maintain?
|
290-300
|
|
|
What is a general, fast way to calculate osmolality?
|
Double sodium
|
|
|
What is the minimum obligatory urine loss in a day?
|
500mL/day
|
|
|
What do osmoreceptors in the hypothalamus lead to when they detect increased osmolality?
|
Thirst
ADH secretion |
|
|
Where is ADH produced?
|
Supraoptic and Paraventricular nuclei of the hypothalamus
|
|
|
Below what level of osmolaltiy would we not expect to see any ADH floating around?
|
280
|
|
|
Describe the neural pathway of baroreceptors in the carotid body and aorta.
|
These baroreceptors send an inhibitory signal to the vasomotor centre in the medulla. Normally, this centre would be stimulating the release of ADH. Normally these are firing and we supress it. If we lose blood pressure though, we lose the inhibitory signal and we release a butt load of ADH.
|
|
|
Where can uria actually play a role?
|
Collecting duct
|
|
|
What can be triggered in response to a drop in effective circulating volume?
|
SNS, which will trigger RAS
ATII: Vasoconstricts Stimulates ADH release Sodium reabsorption in distal tubule through aldosterone Increases sodium reabsorption in the proximal tubule by itself influencing Na/H pump |
|
|
How does atrial natiuretic peptide work?
|
1) It is a powerful vasodilator, targeting the afferent arteriole, leading to an increased GFR and sodium and water excretion.
2) It targets sodium transport, inhibiting sodium reabsorption in the distal tubule and collecting duct. 3) It blocks ADH and renin release and interferes with aldosterone release, hormones that normally increase sodium and water retention. |
