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30 Cards in this Set
- Front
- Back
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The ability of the immune system to mount a response involving cells and soluble factors, resulting in inflammation is:
A. passive immunity B. adaptive immunity C. innate immunity D. selective immunity E. adoptive immunity |
C. Innate Immunity
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The ability of the immune system to mount an immune response involving specific cells, soluble factors, antigen specificity and memory is:
A. passive immunity B. adaptive immunity C. herd immunity D. non-specific immunity |
B. Adaptive Immunity
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The non-clonal response of the immune system to structures or patterns on microbes, leading to the secretion of antimicrobial factors is:
A. found only in humans B. found only in insects C. is shared by plants and animals |
C. Shared by plants and animals
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The first successful recorded experimental variolation with cow pox was carried out by:
A. Louis Pasteur B. Elie Metchnikoff C. Edward Jenner D. Lady Montague |
C. Jenner
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The following individuals; Nils Jerne, David Talmadge and Macfarlane Burnet were responsible for proposing:
A. phagocytic theory B. mechanism of immunity involving serum transfer C. the clonal selection theory D. vaccine theory |
C. Clonal selection theory
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Plasma cells are effector cells differentiated from______________. They secrete_________________.
A. B cells, antibodies B. T cells, antibodies C. Natural killer cells, cytokines D. B cells, cytokines E. monocytes, antibodies |
B cells, Antibodies
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Antigen recognition by T cells is different from B cells. Antigen recognition by T cells is restricted because of the requirement for:
A. major histocompatibility antigens associated with the antigen on antigen presenting cells. B. antigen association with cytokines on antigen presenting cells. C. phagocytosis of antigen by neutrophils |
Major histocompatibility antigens associated with the antigen on antigen presenting cells
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Which of the following is not a primary lymphoid organ?
A. bone marrow B. spleen C. thymus |
Spleen
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The cell surface markers CD4 and CD8 identify the following cell type:
A. B cells B. T cells C. Natural kller cells D. dendritic cells E. macrophages |
T cells
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The ability of the immune system to recognize and respond to antigens months to years after the initial exposure is due:
A. diversity in the antigens B. memory B and T cell development C. memory macrophage development D. host self/nonself recognition E. antigen specificity by natural killer cells |
Memory B & T cell development
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The ability of the immune system to mount a response involving cells and soluble factors, acting interchangeably but without recognition of specific antigen receptors is:
A. passive immunity B. adaptive immunity C. innate immunity D. selective immunity E. adoptive immunity |
Innate Immunity
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Cluster of differentiation (CD)antigens determined by the use of monoclonal antibodies are primarily used to:
A. identify developmental stages of cells B. identify receptors clustered on cells C. mark cells for elimination during development |
Identify developmental stages of cells
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Expression of the markers CD34 and CD38 identify the cells as a:
A. T lymphocyte B. B lymphocyte C. Dendritic cell D. Hematopoietic stem cell E. Basophil |
Hematopoietic stem cell
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Expression of the marker CD3 is associated with:
A. The antigen binding recptor on B cells B. The antigen binding receptor on T cells C. The antigen binding receptor on macrophages |
The antigen binding receptor on T cells
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Thymocytes leaving the bone marrow enter the ___________for additional development and maturation.
A. lymph nodes B. Thymus C. spleen D. mucosal associated lymphoid tissue (MALT) |
Thymus
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The three antigen binding molecules in the immune system are:
A. CD4, CD8 and CD3 B. MHC class I, Intracellular adhesion molecules(ICAMs) and immunoglobulin C. MHC proteins (I &II), T cell receptor and Immunoglobulin |
MHC proteins (I&II)
T-cell receptor Immunoglobulin |
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High endothelial venules (HEVs) are located in the ___________.
A. lymph nodes B. spleen C. bone marrow D. thymus |
Lymph Nodes
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Which of the following cells requires HEVs for extravasation?
A. neutrophils B. Lymphocytes C. Basophils D. Macrophages |
Lymphocytes
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Class I major histocompatibility complex antigens are located :
A. specific immune cells such as lymphocytes B. on all nucleated cells C. only expressed on macrophages and dendritic cells |
On all nucleated cells
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Class II major histocompatibility complex antigens are found on:
A. all nucleated cells B. on specific immune cells such as antigen presenting cells C. only on macrophages D. only on dendritic cells E. only on B cells |
On specific immune cells such as antigen presenting cells
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The two branches of specific immunity are:
A. passive, active B. adaptive, humoral C. cell-mediated, adoptive D. active, herd E. humoral, cell-mediated |
Humoral & Cell-mediated
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Lymphocytes can remain in the blood up to______hours befor homing into a secondary lymphoid organ.
A. 48 B. 72 C. 6 D. 12 E. 1 |
12 hours
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Nurse cells are specialized epithelial cells found in the _________.
A. Bone marrow B. Thymus C. Spleen D. Lymph nodes |
Thymus
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The following antimicrobial peptides, cecropin and drosophins are part of the ___________immunity in insects.
A. innate B. adaptive C. specific |
Innate
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______cells are morphologically unique epithelial cells located at inductive sites in mucosal areas. They activate B cells to produce _______.
A. Dendritic cells, IgG B. M cells, IgE C. M cells, IgA D. Langerhans cells, IgA |
M cells, IgA
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Endogenous antigens are presented to the Tc cells in association with _____________antigens.
A. MHC class I B. MHC class II |
MHC class I
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Exogenous antigens are presented to T helper cells in association with ______________antigens.
A. MHC class I B. MHC class II |
MHC class II
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Which of the following statements highlights the differences between a primary and secondary immune response?
A. The primary response occurs through the activity of effector cells. B. The secondary response occurs through the activity of activated memory cells. C. The magnitude of the primary response is higher than that of the secondary response. |
The secondary response occurs through the activity of activated memory cells
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Which of the following cell death processes would most likely lead to or be associated with an inflammatory response?
A. Necrosis B. Apoptosis |
Necrosis
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Which of the following would not be considered a mechanism for regulating hematopoiesis?
A. regulation of cytokine receptors B. controlling the generation of specific cells by necrosis C. controlling the generation of specific cells by apoptosis D. The control of cytokine expression having activity for specific cell lineages. |
Controlling the generation of specific cells by necrosis
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