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21 Cards in this Set
- Front
- Back
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adaptive immunity
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that part of the immune system that is specific and has memory (B and T cells)
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antibodies
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molecules that are secreted by plasma cells and bind to antigen in a specific manner
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antigen
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classic definition: molecules that have specific sequences to which adaptive immune responses can be generated
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antigenicity
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a property of molecules to which an adaptive immune response can be generated
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antigenic determinant
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syn: epitope. A particular component of an antigen that is recognized by unique lymphocyte receptors (that component of an antigen that is recognized by B or T cells [T cells only recognize antigens displayed with MHC])
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Bursa of fabricius
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tissue where B cells mature from progenitor cells (in chickens)
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complement
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a host defense sustem consisting of soluble and membrane-bound proteins
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chemokines
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small molecules that were originally identified because of their role in attracting cells to a particular region
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cytokines
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molecules that are secreted primarily (but not exclusively) by cells of the immune system. These molecules play an important role in the activation and in down-regulation of immune responses
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determinant
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syn: epitope. A particular component of an antigen that is recognized by unique lymphocyte receptors (that component of an antigen that is recognized by B or T cells [T cells only recognize antigens displayed with MHC])
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epitope
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A particular component of an antigen that is recognized by unique lymphocyte receptors (that component of an antigen that is recognized by B or T cells [T cells only recognize antigens displayed with MHC])
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follicle associated epithelium (FAE)
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that region of the luminal epithelium that is not covered by mucus (part of MALT system)
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germinal center
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that component of a follicle where antigen-induced B cell differentiation occurs
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hapten and carrier
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a small molecule (<6kd) that is not immunogenic unless it binds to a carrier protein, permitting anti-hapten immune response
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hematopoiesis
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a term used to refer to the differentiation of various cell types from a pluripotent stem stell. Cytokines play an important role in this process
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immunogenicity
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syn: antigenicity. refers to a molecule that can serve as teh stimulus for an adaptive immune response
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innate immunity
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that component of immunity in which cells and effectors do not have memory, nor receptors specific for an epitope
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mitogen
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polyclonal activator
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periarteriolar lymphatic sheath (PALS)
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region containing the white pulp
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white pulp
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that region of the spleen within PALS, predominant immune cell is the T cell and is where the primary T cell responses can occur
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tolerance (self tolerance)
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refers to the fact that the immune system is not pathologically activated in the presence of its own antigens
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