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540 Cards in this Set

  • Front
  • Back

How do cytology and histology differ?

Histology is the study of tissues, whereas cytology is the study of cells.

What four ways can we look at anatomy?


1. Macroscopically or Gross; either by region, systematically or superficially.


2. Microscopically (in terms of histology or cytology)


3. Developmentally; in terms of how the body changes through growth and development


4. Abnormality; how the body changes through aging, injury and disease

What are the 6 levels that you consider an organism?

chemically


cellular


tissue


organs


systems


entire organism

What is an organ

a structure with 2 types of tissues

What is an (organ) system?

A group of organs working together to perform a common task/purpose

What is the anatomical position?

stood upright


lower limbs together


arms by side, palms facing upwards

How many body planes are there?

3

What is the coronal body plane

The plane bisecting the organism to separate front from back.



What is dorsal

back

What is posterior

back

What is anterior

front

what is ventral

front

What is the sagittal body plane?

The body plane that bisects the organism to separate the left from the right.

What is the difference between parasagittal and medial-sagittal

parasagittal bisects the organism unsymmetrically, whereas medial-sagittal bisects the organism symmetrically

What is the transverse body plane

The body plane bisecting the organism to separate the top from the bottom, through the medial.

What is inferior

below

what is superior

above

What is lateral

to the side, away from the medial

What is proximal vs distal

proximal means closer


distal means further away

When using proximal/distal what should you take into consideration

the origin

What is the origin for describing proximal/distal of the blood vessels

heart

what is the origin for describing proximal distal of the body

trunk

What 2 groups are the bones of the skeleton characterised into?

axial and appendicular

How many bones are there in the human body

206

What are the axial bones

rib cage; skull and vertebrae column

what are the appendicular bones

pelvis, shoulders and limbs

What is the definition of superficial?

on the surface

Is muscle deep or superficial in comparison to:


a) skin


b) bone

a) deep


b) superficial

What is the arm in anatomical sense

between shoulder and elbow

What would you call the structure from the tips of the fingers to the shoulder

upper limb

What is the leg anatomically?

from the knee to the ankle

What is the region from the hip to the foot called?

lower limb

What cavities are in the Dorsal Body Cavity?

Cranial cavity and vertebral cavity

What cavities are in the ventral body cavity?

thoracic, abdominal and pelvic cavities

What organ is held in the cranial cavity

brain

What organs are held in the thoracic cavity

lungs, heart, oesophagus, thymus, trachea

What organs are in the abdominal cavity

stomach, intestines, liver, gallbladder, spleen, pancreas, kidneys

What organs are in the pelvic cavity?

bladder, large intestine and internal reproductive organs

What cavities are found within the thoracic cavity?

Pleural and pericardial

What separates the thoracic cavity from the abdominal cavity

diaphragm

What cavity holds the heart

pericardial cavity

What is the name of the generic cavity which holds all of the organs within the thoracic cavity, minus the lungs

mediastinum

How many sections can the abdominal region be split into

4 or 9

What are the names of the 4 regions of the abdomen

left upper, right upper, left lower, right lower quadrants

What are the names of the 9 abdominal regions, starting with the top right and ending bottom left

right hypochondriac, epigastric, left hypochondriac, right lumbar, umbilicus, left lumbar, right iliac, hypogastric, left iliac

What structure's role is to carry and protect the spinal chord, support the thoracic/rib cage and protects organs within?

The vertebral column

What are the other functions of the vertebral column?

Weight transfer and absorbs shock fro lower limb. Also provides attachment points for muscles

What are the regions of the spine and how many vertebrae are in each region

Cervial - 7


Thoracic - 12


Lumbar - 5


Sacral - 1 ( 5 fused)


Coccyx - 1 ( 2-5 fused)

What are the two regions of the intervertebral disk and what are their names and functions?

Annulus Fibrosis - concentric rings of fibrous cartilage




Nucleus Pulposes - centrally located structure

Where are the intervertebral disks found?

inferior to C2 and superior to S1

What total length of the vertebral column is made up of intervertebral disks?

25% approx

What is the function of curvatures to the spine

1. body balance - to create head + upper body over centre of gravity


2. Shock absorbtion

What can increase/decrease curvatures in the spine?

Poor posture, disease, age, weight carriage

What is the name for a curvature that starts going away from the body but comes back in

Kyphosis

What is the name for a curvature that starts going inwards towards the body but then goes out?

lordosis

What areas of the spine exhibit lordosis

Lumbar and cervical

What ares of the spine exhibit kyphosis

thoracic and sacral

Define joint and explain their function

a joint is where two bones meet


it allows articulation and mechanical support



What are the 3 categories of functional classification for joints?

Synarthroses - no movement


Amphiarthroses - little movement


Diarthroses - free movement

What are the 3 structural classifications for joints?

Fibrous


Cartilaginous


Synovial

What are the 3 types of fibrous joint?

Suture


Gomphosis


Syndesmosis

What is characteristic of a suture joint

interlocking bones


immovable (synarthroses)


periosteum - continous outer bone layer


fibrous tissue layer

What is characteristic of a gomphosis joint?

Peg in socket


Supported by fibrous ligaments


Very little/no movement (synarthroses)

What characterises a syndesmosis joint?

In between two long bones


Fibrous tissue band/ interosseous membrane


allows forces to pass between bones


small amount of movement (amphiarthroses)

What are the three types of cartilage in the body

hyaline, elastic and fibrocartilage

What are the properties of elastic cartilage

-elastic fibers with collagen and proteoglycans


-rigid but elastic properties


example in external ear

What are the properties of fibrocartilage

strongest cartilage form


more collagen than proteoglycans


thick bundles of collagen fibers


slightly compressable - good at dealing with pressure


example in intervertebral disks

What are the properties of hyaline cartilage

weakest cartilage form


equal amounts of collagen and proteoglycans


collagen fibres equally dispersed


smooth + translucent


reduces friction and absorbs shock


covers bone/articulating surfaces



What are the two types of cartilaginous joints?

Synchondrosis and Symphysis

What is synchondrosis

type of joint found in children or young adults at the end of long bones


replaced with bone as you age


allows for the growth of long bones such as femur in the body


To do with growth rather than movement and so synarthroses

What is symphysis

type of joint generally found in the midline, intervertebral discs and pubic symphysis.


ends of articulating bones covered in hyaline


fibrocartilage in between.


Allows some movement - amphiarthroses

What characterises a synovial joint?

not directly joined


synovial cavity


joined by capsule


synovium - produces synovial fluid


all free moving - diarthroses


hyaline covered articulating surfaces

Name the 6 types of synovial joint

plane


pivot


hinge


saddle


ellipsoid


ball and socket

What characterises a plane joint

sliding or gliding movement


uniaxial movement


eg acromioclavicular joint

What characterises a saddle joint?

convex and concave structures on both articulating surfaces


biaxial movement


eg carpo-metacarpal joint

What characterises a hinge joint?

uniaxial


limited by shape of articular surfaces and strong ligament which also adds support


elbow and ankle

What characterises a Pivot joint?

Rounded process of bone


Rotates within tunnel or ring structure


uni axial rotational movement


atlanto-axial joint

What characterises a ellipsoid or condyloid joint joint?

one spherical articulating surface and one with a complementary depression


biaxial or multi-axial movement


eg metacarpophalangeal joint

What characterises a ball and socket joint?

rounded articular (ball) and concave articular surface (socket)


multi axial


unstable - risk of dislocation


shoulder or hip

What are the limitations of synovial joint movement?

1. the shape and extent of articular surfaces


2. tensions of joint capsule


3. the tensions of ligaments surrounding the joints


4. muscles crossing and acting upon a joint


5. bony parts of joint colliding

What is the difference between ligament and tendons?

ligaments connect bones to bones


tendons connect bones to muscles

flexible but inelastic cord of strong fibrous collagen tissue - ligament or tendon?

Tendon

tough, flexibe, fibrous connective tissue - ligament or tendon?

Ligament

Characterise osteoarthritis?

Osteo = degenerative joint disease


articular cartilage and subchondral bone degenerates


water content of cartilage decreases


osteophytes form on bone margins


heberdens' nodes and bouchards' nodes

Heberdens' nodes are on which joint?

distal interphalangeal

Bouchard's nodes are on which joint?

proximal interphalangeal

Rheumatoid arthritis key features:

chronic inflammation


destruction of articular cartilage and ankylosis of joint


destroys small joints


forms subcutaneous rheumatoid nodes


may affect other tissues

Define ankylosis

where bone locks into least painful position

how does rheumatoid arthritis affect other tissues or organs?

lungs - fibrosis


eyes - episcleritis

Which form of arthritis is due to decrease in water content of cartilage?

osteo

The heart doesn't look like a valentines heart due to it's position in the body. How is it altered?

Rotated anticlockwise and backwards so that from an anterior perspective the Right side is to the front and the left side is to the back

Where is the apex of the heart located?

5th costal space

What are the four borders of the heart and what do they touch?

Superior - great vessels


Inferior - diaphragm


Left- L lung


Right - R lung

What is the base of the heart anatomically?

Posterior side of the heart

What is the anterior surface of the heart touching?

Sternum

What is the cavity that the heart sits in? (doesn't include lungs but does include vessels)

Mediastinum

What is most dominant from an anterior perspective of the heart?

Right ventricle

What separates the right and left ventricles on the anterior surface of the heart?

The anterior interventricular sulcus

What does sulcus refer to?

a groove or recess

What is the name of the sulcus separating the ventricle and atria on the anterior surface of the heart?

Coronary sulcus

What tissue can be found in the sulcuses of the heart?

adipose tissue

What vessel is in the anterior coronary sulcus?

coronary artery

What major vessel is in the anterior interventricular sulcus?

left anterior descending artery

What is the name for small sacs on the atria of the heart? They increase capacity of the heart?

Auricles

What are the major posterior landmarks on the hearts surface

posterior interventricular sulcus


coronary sulcus

What is in the posterior coronary sulcus?

coronary sinus

What is in the posterior interventricular sulcus?

Posterior descending artery either from right or left coronary arteries.

What is the pericardium?

Sac that protects the heart

How many layers in the pericardium

2

What is the outermost layer of the pericardium?

Fibrous pericardium

What are the characteristics of the fibrous pericardium?

tough + inelastic


rests + attached to diaphragm


Open end fused to great vessels

What is the inner layer of the pericardium?

Serous Pericardium

How many further layers make up the serous pericardium?

3

What is the outermost layer of the serous pericardium, describe it

Parietal


fused and inseparable from fibrous pericardium

What is the innermost layer of the serous pericardium, describe it

Visceral layer


continous to epicardium

What lies between the parietal layer and the visceral layer in the pericardium?

Pericardial cavity


Filled with pericardial fluid

What is the purpose of pericardial fluid?

Shock absorption and protection of the heart

How many layers are there of the heart wall?

3

What is the middle layer of the heart wall called?

Myocardium

What is the epicardium?

The outermost layer of heart


Continous with the visceral serous pericardium

What is the centre layer of the heart?

endocardium

Which of the layers of the heart are continous with the endothelium of large vessels?

endocardium

Which of the layers of the heart is the cardiac muscle?

Myocardium

Which chamber of the heart receives oxygenated blood from a vessel? (Also name the vessel)

Pulmonary vein


Left atrium

Which chamber of the heart pumps deoxygenated blood out of the heart?
Where does it go and via which vessel

Right ventricle


Lungs


Pulmonary arteries



Which chamber of the heart is connected to the vena cava. What blood does it contain?

Right atrium


Deoxygenated

What chamber of the heart has the thickest walls? Where does it pump blood too to warrant such powerful muscle?

Left Ventricle


Systemic circulation / Body

What are the two types of valves in the heart?

atrioventricular + semilunar

Where is the only bicuspid valve in the heart?

Left atrio-ventricular valve

If there is one bicuspid valve, what are the other 3?

Tricuspid

Where are the two semilunar valves located?

At the base of the aorta and the pulmonary artety


(between ventricles and vessels)

What types of muscles contract to open the valves in the heart

papillary

What connects heart valves to the contraction muscles to open/close them?

chordae tendinae

What is the fossa ovalis's fetal counterpart

Foramen ovale

What is the function of the foramen ovale?

connect right and left atria


bypass pulmonary circulation

What causes the foramen ovale to close and eventually form the fossa ovalis?

the first breath causing a change in pressure


flap of muscle closes over hole

What are the musculi pectinatae

comb like muscle


folding increases reserve for increased atrial capacity

What is the crista terminalis

connection between auricles


smooth surfaced cresent of muscle


right atria


SA node location

What are trabeculae carneae and where are they located?

ventricles


protrusions of muscle


prevent suction from sticking sides of ventricle together

Off of which chamber would you find the left auricle?

Left atria

Which vessel brings deoxygenated blood into the right atria

vena cava

Which vessel takes deoxygenated blood away from the heart?

pulmonary artery

Which vessel takes oxygenated blood away from the heart?

aorta

Which vessel brings oxygenated blood towards the heart

pulmonary vein

How many branches are on the aortic arch

3

What does the second branch of the aortic arch do and what is it called?

take blood to left side of body


common carotid

what does the third branch of the aortic arch do and what is it called?

take blood to left arm


left subclavian



What does the first branch of the aortic arch do and what is it called.

Brachiocephalic artery


splits into right subclavian and right common carotid




takes blood to right arm (RS) and right side of body (RCC)

How does the blood in the heart reach the heart?

through the coronary artery (via the aorta)

The right coronary artery branches separate into what two vessels?

posterior interventricular


right marginal

The left coronary artery branches into what vessels

circumflex


left marginal


diagonal


anterior interventricular

What are the venous vessels of the heart?

small cardiac vein


middle cardiac vein


left posterior ventricular vein


left marginal vein


great cardiac vein

What do all of the veins of the heart empty into?

coronary sinus

Where does the coronary sinus take the deoxygenated blood from the heart

right atrium

The RCA (right coronary artery) supplies blood to where?

RA


Most RV


Some LV


1/3 of septum


SA node in 60% of people


AV node in 80% of people

What regions does the LCA (left coronary artery) supply blood to in the heart?

LA


Most LV


Some RV


2/3 septum


SA node in 40% of people


AV node in 20% of people

What the 4 layers of the GI tract wall?

mucosa


submucosa


muscularis


serosa



What does the mucosa do in the GI tract?

mucous membrane


lines GI tract


secrete mucus


varying epithelium

What does the submucosa do in the GI tract?

layer of connective tissue


blood vessels


lymph vessels


nerves

What does the muscularis do in the GI tract? How many layers are in it and how does each differ?

made up of 2 layers of smooth muscle


inner = circular muscle


outer = longitudinal


contracts or dilates lumen

What does the serosa do in the GI tract?

connective tissue covering


secretes fluid externally


lubricates outside of GI tract

What marks the superficial boundaries of the oral cavity?

Ant = lips


Laterally = Cheeks


Sup = palate


Inf = tongue



What makes up the exterior, interior and middle of the lips?

Exterior = skin


Interior = stratified squamous epithelium


Middle = orbicularis oris muscle

What attaches the lips to the gums

labial frenula

What are the two muscles involved in chewing?

orbicularis oris


buccinator

What gives the rounded contour to the cheeks

buccal fat pad

What cell type in on the inside of the cheek?

stratified squamous epithelium

What are the two regions of the palate, what are their relative sizes and what is the boundary?

Hard


2/3 anterior portion




Soft


1/3 posterior portion




The back teeth line and palatine bone marks the difference

What gives the hard palate it's hardness?

maxillae and palatine bones

What makes up the soft palate

skeletal muscle and connective tissue

What is the name of the structure that visibly dangles at the back of the mouth?

Uvula

What is the name of the arches at the back of the oral cavity in the roof of the mouth?

Pharyngeal arches

What is the name of the most anterior pharyngeal arch?

palatoglossal arch

What is the name of the posterior pharyngeal arch?

palatopharyngeal arch

What is the name of the arched opening at the back of the mouth that leads to the pharynx

Fauces

What portion of the tongue is freely moveable?

2/3rds

What attaches the tongue to the floor of the mouth?

lingual frenulum

What is the posterior pharyngeal portion of the tongue attached to?

hyoid bone


epiglottis


oropharynx

What separates the front and back regions of the tongue?

sulcus terminalis

What is different about the structure of the pre-sulcal and post-sulcal tonge?

Pre has lingual papillae (tastebuds)


Post has lingual tonsils (lymphoid nodules)

How many muscles are their in the tongue?

7 pairs

What are the two classifications of the tongue muscles and how do they differ?

intrinsic and extrinsic


IN = change shape of tongue


EX = gross movement of the tongue

How many muscles deal with gross tongue movement?

3 pairs

How many muscles deal with intrinsic tongue movement?

4 pairs

What do we split the dentition into when studying the teeth?

quadrants

How many teeth do children have

20

What types of teeth do children have and how many of each in a single quadrant?

2 incisors


1 canine


2 molar

How many teeth do adults usually have?

32

How many adult teeth are there in a quadrant? Name the tooth types.

2 incisor


1 canine


2 premolar


3 molar

What is the last adult tooth to emerge and at what age?

Wisdom teeth or 3rd molar


25 years old

What is the name of the bone in which teeth sit?

alveolar bone

What is the anatomical name for gums

gingiva

What is the difference between a clinical crown and an anatomical crown?

Clinical crown - all of the enamel that can be seen




Anatomical crown - all of the enamel, even the parts hidden by the gum line

What is the top layer of the tooth called?

Enamel

What is the layer of the tooth deep to the enamel called?

dentin

What is the layer of the tooth deep to dentin called?

pulp cavity

What is the apical foramen

the point where the root canal leaves the tooth and enters the jaw bone

what is the name of the ligament that hoes the tooth and the alveolar bone together?

periodontal ligament

What 3 general regions can the anatomy of a tooth be subdivided?

crown


neck


root

What is the name of the layer between the tooth and the periodontal ligament?

cementum

Where does the pharynx connect to the digestive system?

oesophagus

Where does the pharynx connect to the respiratory system?

larynx

What are the 3 regions of the pharynx

nasopharynx


oropharynx


laryngopharynx

Where is the nasopharynx

behind nasal cavity

Where is the oropharynx

behind the oral cavity

Where is the laryngopharynx

behind larynx

What lines the nasopharynx?

ciliated pseudostratified columnar epithelium

What lines the oropharynx and laryngopharynx

moist stratified squamous epithelium

What are the 3 muscles of the pharynx

superior, middle and inferior muscles

How are the 3 muscles of the pharynx joined?

posterior walls of oropharynx and laryngopharynx

What is the purpose of the muscles of the pharynx?

constriction for swallowing etc

How long is the oesophagus and what does it connect?

25cm long


laryngopharynx to the stomach

What cavities does the oesophagus pass through?

thoracic to abdominal

The oesophagus passes directly through the diaphragm. What is the name and location (vertebrae) of this point?

oesophageal hiatus




T10

How many sphincters are there in the oesophagus?

2

What are the oesophageal sphincters

upper sphincter near epiglottis


lower (Cardiac) sphincter on entrance to stomach

What letter shape is the stomach? It gives rise to the lesser and greater curvatures

J

What is the name for folds in the wall in the stomach?

Rugae

The region of the stomach directly connected to the esophagus is known as what?

Cardiac region

The bottom region of the stomach is known as what?

pyloric region

What is the name of the bottom sphincter in the stomach?

pyloric sphincter

What is the name for the top region of the stomach

fundus

What cell type is in the lining (mucosa) of the stomach?

simple columnar epithelium

What is special about the muscularis of the stomach

there is a third (inner) layer of oblique muscle

What are the two portions of the respiratory system?

Conditioning Portion


Gasseous Exchange / Respiratory Portion

What is the purpose of the conditioning portion of the Respiratory system?

humidifies, warms and filters air




also used for sound production and sense of smell

What two regions can the conditioning portion be split into?

Upper and lower respiratory tract

What is the upper respiratory tract?

nasal cavity


paranasal sinuses


pharynx


larynx

What is the lower respiratoy tract

trachea


bronchi


bronchioles until the terminal bronchioles

How many generations of dividing occur between the trachea and the alveoli

about 25

What pattern do the bronchi divide in?

fractile

What is the name for the splitting of the trachea into the two primary bronchi?

carina




or tracheal bifurcation

What are the two surfaces of the lungs called?

costal and mediastinal surfaces

How many lobes are there in the right lung?

3 - superior, middle and inferior

How many lobes are there in the left lung?

2 - superior and inferior

How many fissures are there in each lung?

Right - 2 - oblique and horizontal


Left - 1 - oblique

What is the function of type 1 pneumocytes

forms barrier in alveoli for gas exchange

What part of pneumocyte type 1 form makes it good at it's function?

thin/squamous cells

What is the function of type 2 pneumocytes and how does their form enable this?

Provide pulmonary surfactant for alveolar surfaces




Cuboidal shape with laminar bodies


cuboidal = lots of multilaminar bodies


multi laminar bodies produce the surfactant

What are the names of the two pleural membranes?


What is each attached to?

Outer = parietal, attached to costal wall

Inner = visceral, attached to lung surface


What is between the two pleura?

pleural cavity


small amount of fluid


negative pressure

What structures are required for quiet breathing

mainly just the diaphragm

What structures are required for active breathing

diaphragm and intercostal muscles

What structures are required for extreme breathing

diaphragm, intercostal muscles and accessory muscles of respiration in the trunk and neck

What happens to the position of the diaphragm when it contracts?

moves down


becomes flatter



What would happen if air got into the pleural cavity? AKA Pleural effusion

the two pleura wouldn't stick to each other as negative pressure would be lost


lung would collapse/recoil as nothing is holding the visceral pleural out to stretch the lung



How many layers of intercostal muscles are there?

3

What is different about the external and internal intercostal muscles?

lie in a different direction

Which of the intercostal muscles is involve in breathing in? What does it do?

external


lifts the ribs up and out

Where are the intercostal vessels and nerves located?

protected underneath the rib bones

How many ribs are there in the human body

12 pairs

What are the 3 classifications of ribs

true


false


floating

What category are the most superior set of ribs and how many are there?



Ribs 1 - 6


true ribs

What is the definition of a true rib

articulate with the sternum via costal cartilages

What are the middle set of ribs called and how many are there?

Ribs 7 - 10


False ribs



What is the definition of a false rib

articulate with costal cartilages above rather than sternum

What is the definition of a floating rib. Which ribs are they?

Ribs that do not articulate anteriorly


Ribs 11 and 12

What part of the rib connects to the transverse process of the vertebrae

tubercle of the rib

What part of the rib connects to the vertebral body?

head of the rib

What is the name of the bone that sits superior to the sternum and medial to the clavicles?

manubrium

What is the name of the process of bone at the inferior end of the sternum?

xiphoid process

What is the name of the tendons that connect the vertebrae to the diaphragm?

Left and right crus

What is the space between the ribs and the diaphragm called?

costo-diaphragmatic recess

What is the structure of the diaphragm

parachute shaped muscle


central tendon


radial muscles originating from the ribs, sternum and spine.

How many rings of cartilage does the trachea have?

16 - 25

What structures pass through the root of the lung?

primary bronchus


pulmonary artery


pulmonary veins (2)


bronchial vessels


lymphatics


autonomic nerves

Are salivary glands exocrine or endocrine?

exocrine - they have a duct

Name the major pairs of salivary glands

parotid


submandibular


sublingual

What are the minor salivary glands called on the cheek, tongue, palate and lips respectively?

Cheek = buccal


Tongue = lingual


Palate = palatine


Lips = Labial

What is the cheekbone called?

Zygomatic arch

Which pair of salivary glands are the largest?

Parotid

Where does the parotid gland's duct secrete saliva?

Near the second upper molar

Which salivary gland is below the tongue?



Sublingual



Where is the opening for the submandibular duct?

at the side of the labial frenulum

What is notable about the duct for the sublingual gland?

It is not we definied


Glands open into floor of oral cavity through 10-12 small ducts

What type of gland are the three main salivary glands?

Compound acinar/alveoli glands


What can be said about saliva from each salivary gland?

It is different gland to gland

What two cell types form salivary glands?

serous cells


mucous cells

Which salivary gland is comprised mainly of mucous cells?

sublingual

Which salivary gland is comprised mainly of serous cells?

Parotid

Which salivary gland is comprised of a roughly even mixture of serous and mucous cells?

submandibular

What are the two main lobes of the liver called?

Right and left lobes

What are the two secondary lobes of the liver called?

Caudate and quadrate lobe

To which primary lobe, do the secondary lobes belong?

Right lobe

What are the features of the anterior surface of the liver?

falciform ligament


round ligament

What organ is visible from the posterior surface of the liver?

Gall bladder

What layer almost completely covers the outside of the liver?

visceral peritoneum

What vessel separates the right and caudate lobe?

Inferior vena cava

What is the shape of a lobule of the liver?

hexagonal

What cells are found in the sinusoid regions of the liver lobules?

Kupffer Cells

What is a portal triad and where is it located?

in the corner of each lobule


bundle of 3 vessels


- branch of hepatic artery


- branch of portal vein


- branch of heptic bile duct

The central veins in each liver lobule will eventually join together to form what vessel. This eventually leads to what larger vessel

hepatic veins


join inferior vena cava

Small vessels from the bile duct within the hepatic plates which collect bile produced in the liver are called what?

Canaliculi

At what point does the common hepatic duct leave the liver? Where does it head?

Porta hepatis


towards the duodenum

Where does the liver get 72% of it's blood from?

hepatic portal vein

Why does deoxygenated blood from other organs flow through the liver before going to the heart?

It brings products from digestion that the liver processes


-detoxification


-metabolism


-excretion of bilirubin


-storage of vitamins etc




What do Kupffler cells do?

phagocytosis - immune response

What enters the liver at the porta hepatis

hepatic artery + hepatic portal vein

Which organ does blood from the stomach pass through before passing into the vena cava?

liver

What are the names of the 3 midline branches of the abdominal aorta

coeliac trunk


superior mesenteric


inferior mesenteric



From which branch of the the abdominal aorta does the hepatic artery arise from?

coeliac trunk

Along with the superior mesenteric vein, what other vein empties into the hepatic portal vein

splenic vein

What are some of the functions of the liver?

Metabolism


Detoxification


Excrete bilirubin


Storage


Synthesis


Phagocytosis

What is the carbohydrate metabolism in the liver?

glucose to glycogen


glycogen to glucose


amino +lactic acids to glucose

what is the lipid metabolism in the liver?

store triglycerides and synthesises lipproteins

What does the liver store?

glycogen, vitamins and minerals

what is synthesised in the liver?

bile salts used for emulsification and absorption of cholesterol

What fruit does the gall bladder look like?

pear

to what surface of the liver is the gall bladder attached, and via what?

via cystic duct

inferior surface


What are the names for the layers of the gall bladder?

tunics


- inner mucosa


-muscularis


-serosa

What is a feature of the inner mucosa of the gall bladder?

rugae

What is the function of the gall bladder

store + concentrate bile

Which retroperitoneal gland lies transversely and posterior to the greater curvature of the stomach?

pancreas

What are the 3 regions of the pancreas?

head body and tail

Is the pancreas exocrine or endocrine

both

What is endocrine region of the pancreas? What are the functions?

cells are pancreatic islets which secrete hormones directly into blood stream

Which part of the pancreas makes up 1% and 99% comparatively?

1% - endocrine


99% = exocrine

What is the exocrine region of the pancreas and what is the function?

acing cells


secrete pancreatic enzymes into digestive system via a duct

What to ducts form the common bile duct

cystic duct and common hepatic duct

pancreatic secretions pass into small ducts which unite to form which two ducts

main pancreatic duct and accessory duct

what is the different between the main pancreatic and the accessory duct?

Main pancreatic = joins common bile duct



Accessory = empties directly into the duodenum


At what point do the main pancreatic duct and common bile duct meet? Where do they enter the duodenum

hepatopancreatic ampulla




enter at major duodenal papilla

What is the name of the layer that joins organs to each other and abdominal walls?

peritoneum

What are the 4 parts of the large intestine?

ascending, transverse, descending and sigmoid

Which part of the colon is S shaped?

sigmoid

what is the name of the large sheet of fibrous tissue that covers the small intestine if the front wall of the abdomen was removed??

greater omentum

what are the 3 regions of the small intestine

ileum, duodenum, jejunum

what is the name of the sheet that connects the small intestine to the wall of the dorsal peritoneum

mesentery proper

what is the name of the sphincter at the end of the small intestine

ileocecal junction

what is the shape of the first part of the duodenum

c shaped

what is the region that separates the jejunum from the duodenum?

duodenojejunal flexure

what is the only part of the duodenum that is peritonised

short superior region

What is the name for the circular folds of the small intestine mucosa?

plicae circularis

As you go down the small intestine what is noticeable about the cell wall features?

vili less prominent


diameter and thickness of wall decreases



what are peyer patches

lymphoid follicles in submucosa of ileum

what is the name for the special mucus secreting glands of the duodenum

brunner

what 4 types of columnar epithelium cover vili in the small intestine?

absorptive


goblet


granular


endocrine

What is a lacteal in the small intestine

lymph vessel in villi

What are the functions of the large intestine

reabsorbs water


compact intestinal contents into faeces


absorb vitamins


home to comensal bacteria


storage of faeces

what is the name of the region of the large intestine connected to the ileum

cecum

what is the name of the corners of the large intestine between ascending + transverse colon and the transverse and descending colon?

hepatic + splenic flexures

what structure protrudes posteriorly from the cecum?

appendix

What is the mucosal lining of the colon formed into?

crypts - straight tubular glands

what are haustra?

permit expansion and extension of the large intestine (the cloud-like shape)

what is the name of the 3 longitudinal bands of the colon

taeniae coli

what are fat filled pouches of the colon?

epiploic appendages

How long is the rectum

12cm

what are transverse rectal folds known as

the rectal valves

What cells are present in the rectal mucosa

simple columnar epithelium


goblet cells

what are anal columns and what is between them?

longitudinal folds of epithelium


anal sinuses between

Which anal sphincter is voluntary and which one is involuntary?

internal = involuntary


external = voluntary

Where is the calyx

kidney


urine passes through towards pelvis of kidney

Where is the hilium

collecting area of kidney

What does the spinal cord run through?

vertebral column

Between which vertebrae does the spinal chord run through

from foramen magnum -> L1-2

How many pairs of spinal nerves does the spinal cord give rise to?

31 pairs

All pairs of spinal cord nerves are mixed except for 2, true or false?

False - all pairs re mixed nerves

Is the spinal cord uniform in diameter?

No

Where is the spinal cord widest?

the cervical and lumbosacral enlargments

What is the name of the tapered inferior end of the spinal cord?

conus medullaris

What is the name of the location of lumbar and sacral nerve roots?

caude equina

Where is the inferior end of the spinal cord?

L1 - L2

What is the first meninges of the spinal cord to develop, this occurs at 8 weeks of gestation?

Dura mater

Where is the root of the 1st sacral nerve throughout development

S1 vertebrae



What is the position of the conus medullaris throughout the development of the spinal cord?

14 weeks gestation = S1


Birth = L3


Adulthood = L1

How many weeks after fertilisation does the pia mater and arachnoid mater develop?

14 weeks

What are the 4 main protective structures of the spinal cord?

Vertebral column


Ligaments


Meninges


CSF

What does the vertebral column do?

- solid + flexible protective casing for spinal cord


- intervertebral discs to absorb shock


- transmit weight from trunk to lower limb


- attachment point for rib + muscles

What is the name of the ligament that limits potentially damaging movement in the spine?

ligamentum flavum

What are the 3 main ligaments of the spinal cord?

anterior longitudinal


posterior longitudinal


ligamentum flavum

What is the role of the meninges

3 protective layers


contain blood supply and CSF


barrier for neurotoxins

What is CSF?

cerebrospinal fluid


nourishes


cord suspended within it

How many segments and how many vertebrae in each of the 5 regions of the spine?

Cervical


- 8 segments


- 7 vertebrae




Thoracic


- 12 segments


- 12 vertebrae




Lumbar


- 5 segments


- 5 vertebrae




Sacral


- 5 segments


- 5 fused vertebrae




Coccyx


- 1 segment


- 4 fused vertebrae

Which regions of the spine are convex posteriorly

thoracic


saccral

What regions of the spine are concave posteriorly?

cervical


lumbar

Between which meninges is CSF located?

pia mater and arachnoid mater

Between which meninges is the subdural space?

arachnoid mater and the dura mater

What is the location of the epidural space in relation to the dura mater

superficial to the dura mater

What is the name of the flat membrane formed from pia mater

lingamentum denticulum

Where is the lingamentum denticulum located?

along the midline between the dorsal and the ventral nerve roots

What 3 groups of arteries supply the spinal cord?

anterior spinal artery


posterior spinal arteries


radicular arteries

Describe venous drainage of the spinal cord

anterior and posterior median spinal veins


anterolateral and posterolateral paired veins


anterior and posterior radicular veins


internal vertebral venous plexus

Where are the anterior and posterior median spinal veins located?

along the midline

Where are the anterolateral and posterolateral paired veins located?

near lines of attachment of ventral and dorsal roots

Where is the internal vertebral venous plexus located

in the epidural space

What produces CSF?

choroid plexus

Where are the choroid plexuses located?

one in each ventricle

Once produced, where does the CSF flow?

through the ventricles and into the subarachnoid space

What does CSF flow through to get from the ventricles to the subarachnoid space?

the cerebral aqueduct and then thee median and lateral apertures

What part of the spinal cord does CSF flow through when leaving the brain?

the central canal

How is CSF absorbed into the dural venous sinuses?

via arachnoid vili

What procedure is carried out to obtain CSF from a patient?

a lumbar puncture

where does a lumbar puncture take CSF from?

subarachnoid space

Where is the needle inserted for a lumbar puncture? Why here?

between L3 and L4 or L4 and L5


this is inferior to the spinal cord - avoid damage

What is a characteristic of the subarachnoid space in the region where lumbar punctures are carried out, which makes this procedure easier.

Lumbar cistern - an expanded subarachnoid space




also inferior to spinal cord- no risk of damage to nervous tissue

What is the posterior horn of the spinal cord?

made of grey matter


central part of cord


posterior



What information does the posterior horn carry (which direction)

sensory - afferent information


I - VI


noxious proprioceptive

What information does the anterior horn of the spinal cord carry

motor (efferent information)


VIII - IX



What is the grey matter of the spinal cord

posterior, anterior and lateral horn.

Descending tracts of the spinal cord carries what information?

motor - efferent

What are the two groups of descending tracts in the spinal cord?

pyramidal and extrapyramidal

What is another name for pyramidal tracts?

corticospinal tracts

What kind of movement do pyramidal or corticospinal tracts innervate?

voluntary

What kind of movement does extrapyramidal tracts innervate?

everything that isn't motor

What is another name for extrapyramidal tracts?

indirect pathways

What are the two neurones that are involved with the motor pathways?

upper motor neuron and lower motor neuron

What is the final common pathway for all muscles?

anterior horn motor neurone

What kind of information do ascending tracts carry?

sensory

What are the 4 types of ascending tracts

posterior column


spinothalamic


spinolimbic/spionreticular


spinocerebellar

Which tracts of the spinal cord send impulses to the sensory cortex

posterior column and spinothalamic pathways

Which ascending tracts of the spinal cord do not contribute to sensory perception, and where does their impulse go to?

spinocerebellar tracts


cerebellum

What is the pathway for sensing fine touch, proprioception and vibration?

primary sensory neurone


cross midline in medula to secondary sensory neuron


synapse with other sensory pathways in thalamus


sensation perceived in primary somatic sonsory cortex

What is the pathway for sensing noiception, temperature and coarse touch?

primary sensory neurone sneds impulse to secondary sensory neurone in the spinal cord. Sencondary sensory neuron sends impulse to thalamus to synapse with other sensory pathways


sensation perceived in primary somatic sensory cortex

What are the White matter motor/efferent pathways of the spinal cord?

lateral corticospinal tract


rubrospinal tract


reticulospinal tract


tectospinal tract


vestibulospinal tract


medial corticospinal tract

What are the white matter sensory/afferent pathways of the spinal cord?

posterior column


spinocerebellar tract


spinothalamic tract


spino-olivary fibers

In the efferent lateral corticospinal tract of the spinal cord, are the bands of nerves arranged with the most superficial bands supplying the most superior regions of the spine or the most inferior?

Saccral is most superficial


then lumbar, thoracic and then cervical.




The most superficial regions go to the most inferior regions.

In the afferent posterior column of the spinal cord, does the tissue that leads to innervate the cervical region most lateral or medial?

lateral


from medial to lateral the regions are ascending;


i.e.


medial - sacral nerves


then - lumbar, thoracic,


lateral - cervical

What is the function of the spinal cord?

reflexes


carry sensory info from the body to the brain


carry motor info from brain to body

What are the key pieces of motor information sent from brain to body via spinal cord?

voluntary movement


posture


breathing

What is somestesis

sensing touch

what is thermosensation

sensing temperature

what is nociception

sensing pain

what is kinesthesia

sensing position and movement

Briefly outline a spinal reflex

stimulus - i.e. burnt hand


impulse flows towards spinal cord away from receptor along afferent neurone dendrite


throough interneuron


through efferent neurone


impulse to effector organ


.e. muscle contraction

What are the two divisions of PNS

sensory and motor


(AKA afferent and efferent)



What are the 2 divisions of the sensory or afferent nervous system

somatic or visceral

give examples of somatic sensory stimuli

touch


pressure


pain


vibration


temperature

give examples of visceral sensory stimuli

stretch


temperature


chemical change


irritation in viscera


nausea

What are the two divisions of the motor or efferent nervous system?

somatic or autonomic nervous system

The majority of spinal nerves emerge where in relation to their corresponding vertebrae?

inferior to vertebrae

What are the exceptions to the general rule for spinal nerves emerging inferior to corresponding vertebrae?


C1 and C8

Where does spinal nerve C1 emerge?

above atlas

Where does spinal nerve C8 emerge?

below C7

What is the name for an area innervated by a single spinal nerve

dermatome

What dermatomes do cervical nerves innervate?

upper limb and body

what dermatomes do thoracic nerves innervate

trunk

what dermatomes do the lumbar and sacral nerves innervate?

lower limbs

What specific functions are attributed to the cervical nerves?

breathing


heart rate


upper limb movements


head and neck movemments

What specific functions are attributed to the thoracic nerves?

sympathetic tone


trunk stability

What specific functions are attributed to the lumbar nerves?

lower limb movements

what specific functions are attributed to the sacral nerves?

bowel and bladder function

What is paralysis

loss of motor function

what is paraesthesia

loss of sensation

what is hemiplegia?

loss sensation or movement in right or left half of body

what is paraplegia?

loss of sensation or movement in the lower half of the body

what is quadriplegia?

the loss of sensation or movement below the head or neck

What is the origin and function of the spinothalamic tract

Origin - dorsal horn of spinal cord


F - conveys info about pain and temperature

What is the origin and function of spinolimbic, spinomesencephalic and spinoreticular tracts

O - dorsal horn of spinal cord


F - non localised perception of pain, arousal, reflexive, motivational and analgesic responses to nociception

What is the origin and function of the spinocerebellar tract

O - peripheral receptors or dorsal horn of spinal cord




f - proprioceptive information, info on activity in upper motor neurone pathways and spinal interneurones

Who wrote Cerebra Anatome, the first book about the brain

Thomas Willis

What is the circle of Willis?

where branches of the basilar artery meet with the middle cerebral and internal carotid arteries.



What are the 3 main regions of the brain

Hindbrain

Midbrain


Forebrain

What are the 2 divisions of the forebrain

telencephalon


diencephalon

Which portion of the forebrain is anterior?

telencephalon

What is another word for forebrain

prosencephalon

What is another word for midbrain

mesencephalon


What are the two regions of the hindbrain

metencephalon


Myelencephalon

What is another word for hindbrain

myelencephalon

What are the subdivisions of the tenelcephalon

cortex


basal ganglia


limbic system

What are the subdivisions of the diencephalon

thalamus


hypothalamus

What are the subdivisions of the hindbrain

pons, cerebellum and medulla

What are the Lobes of the brain called ( remember the one that is deep)

frontal


parietal


occipital


temporal


limbic

What is the name for the groove between the parietal lobe and frontal lobe

central sulcus

What is the name for the groove between the temporal lobe and frontal lobe

lateral sulcus

What is the name of the sulcus, posterior to the central sulcus that runs deep between the limbic and frontal lobes?

sulcus cinguli

What is the name for the sulcus deep to the parietal lobe and superficial to the limbic lobe

sub-parietal sulcus

What is the name of the sulcus between the parietal and occipital lobes?

parieto-occipital sulcus

Where are the 3 brodmann areas?


- give their names if they have them or locations.

Area 41/42 - Temporal lobe


Area 44/45 - Broca's area - Temporal lobe


Area 17/18 - Occipital lobe

Where is the primary motor cortex located

frontal lobe


precentral gyrus


anterior to central sulcus



What are the main areas controlled by the primary motor cortex

hand and face

Does the primary motor cortex control voluntary or involuntary movement

voluntary

What are the 4 areas of motor planning

primary motor cortex


supplementary motor area


broca's area


premotor area

What is the function of the primary motor cortex

control voluntrary movements

What is the function of the premotor area

control of trunk


anticipatory posural adjustments



what is the function of the supplementary motor area

initiation of movement, orientation planning, bimanual sequential movements

What is the function of broca's area?

motor control of speech

Damage to motor planning areas can lead to what two conditions?

Apraxia and Broca's aphasia

What is Apraxia

inability to perform movements despite intact muscles

What is aphasia

impaired speaking and writing

Where is the primary visual cortex?

At the back of the brain

What is the path of visual information from the eyes to the primary visual cortex?

eyes


optic nerve


via optic chiasm


via thalamus


to visual cortices

The right eye detects something in the right visual field. Which side of the brain does the optic nerve go through?

Left

Where is the point where the two optic nerves cross from right and left eyes to the opposite brain hemispheres?

optic chiasm

What visual information is discriminated by the primary visual cortex/

shape, size, location and texture

What visual information is obtained in the secondary visual cortex?

colour and motion

Where does the information from the eyes get conveyed, after analysis in the secondary cortex?

rest of cortex for response

What is Broca's language centre?

region of frontal lobe


control movement of face involved in speech

What do lesions of the broca's language centre result in

expressive aphasia

What is the difference between expressive and receptive aphasia

expressive - difficulty with verbal expression


slow, laboured speech. Telegraphic style




Receptive - difficulty understanding speech of others - lose ability to monitor their conversation

Who was Pierre Paul Broca?

french pathologist


assigned motor speech function to inferior frontal gyrus

Who was Carl Wernicke?

german neurologist


worked on language processing

Where is Wernicke's area?

superior temporal gyrus


left hemisphere

What does Wernicke's area do?

helps to understand spoken word

The prefrontal cortex has links with all parts of neocortex except from where...

primary motor and sensory

How does the prefrontal cortex link to the contralateral side of the brain?

corpus callosum

What kind of brain function is the frontal cortex involved in

executive function;


- abstract though


- planning


- decision making


- judgment


- anticipating outcome


- social behavioru

What are schizophrenic negative symptoms associated with, in terms of the frontal lobe?

hypofrontality

What is the corpus callosum made of?

large band of white matter



What are the substructures of the corpus callosum?

genu


rostrum


trunk or body


splenium

What does the corpus callosum do?

connect left and right hemisphere

Where is the olfactory cortex located?

on the lateral sulcus between frontal and temporal lobes

What is the cortex posterior to the central sulcus

somatosensory cortex

What is the ridge along the midline of the cerebellum called"

vermis

What are the two lobes of the cerebellum called?

anterior and posterior lobes

Which lobe of the cerebellum is bigger?

posterior lobe

The small bands of the cerebellum are called...

folia

What separates the two lobes of the cerebellum>

primary fissures

What are the right and left sides of the cerebellum called?

hemispheres

After how many days into gestation does the cerebellum form, approximately?

50 days

Lesions of the vermis can cause what

inability to stand upright


nystagmus


impaired eye scanning

Tumours that cause lesions of the vermis of the cerebellum are called;

medulloblastoma

Diseased anterior lobes of the cerebellum can cause what symptom

staggering, drunken gait when sober

What can cause disease to the anterior lobe of the cerebellum?

Chronic alcoholism

Disease of the neocerebellar cortex can cause what symptoms

incoordination of voluntary movements


action tremor

What specifically in the neocerebellar cortex becomes diseased causing action tremors?

superior cerebellar peduncle

What is the basal ganglia?

important subcortical system


regulate voluntary movement

What substructures are in the basal ganglia

striatum


paalidum


sub thalamic nucleus

What makes up the striatum of the basal ganglia?

caudate nucleus


putamen

What makes up the pallidum of the basal ganglia

internal and external globes pallidus

What pathway links the substrata nigra and striatum of the basal ganglia

nigrostriatal pathway

What neurotransmitter is used in the nigrostriatal pathway during motor activity?

dopamine

What disease is caused by degradation of the nigrostriatal dopamine neurones? This is the cause of the motor symptoms of the disease?

Parkinsons

What is the most superior part of the basal ganglia

caudate nucleus

What is the most lateral part of the basal ganglia

putamen

What is median to the putamen of the basal ganglia?

globus pallidus

The substantial nigra is the most inferior part of the basal ganglia, what is directly superior to it?

subthalamic nucleus

What is the limbic system;s function

emotional response


- fear


- anxiety


-aggresion


- pleasure




plus


memory appetite and sleep

What are the key structures of the limbic system?

cingulate gyrus


fornix


thalamus


stria terminalis


septal nuclei


amygdala


hippocampus


hypothalamus

What role does the septal nuclei play in the limbic system

regulate social behaviour

What role does the amygdala play in the limbic system

fear and anxiety




social learning (interpret facial expression, body language, social signals)

What role does the hippocampus play in the limbic system

learning, memory, response to stress and mood




convert short term to long term memory



What role does the hypothalamus play in the limbic system

neuroendocrine stress response


sleep


appetite


body temp


reproductive functions



lesions of the hippocampus lead to...

memory impairments

Where is the amygdala?

temporal lobe


anterior to hippocampus

Lesions of the amygdala can result in?

fearless behaviour

risk taking


poor social judgement



Heightened activation of the amygdala is linked to what disease?

PTSD


anxiety disorders

What size is the amygdala in


a) children with autism




b) schizophrenic patients




in relation to the normal human size

autism - larger




schizophrenia - smaller

Where is the hypothalamus located?

anterior/inferior to thalamus


floor of 3rd ventricle

Where does the limbic "reward pathway" run from and to?

from ventral segmental area




to ventral striatum (nucleus accumbens)

How does addiction relate to the reward pathway?

loss of behavioural control over drug taking


stimulates reward pathway