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132 Cards in this Set

  • Front
  • Back
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What is matter made up of?

Atoms

Why do atoms join together?

To form chemicals with different characteristis

To form...

What do chemical characteristics determine and at what levels?

They determine physiology at the molecular and cellular levels

P at the M and C levels

What is an atom made up of?

Protons, Neutrons, and Electrons

P, N, E

What charges and the type do protons, neutrons, and electrons have?

Proton (positive) 1 mass unit,


Neutron (neutral) 1 mass unit, Electrons (negative) low mass

Pos 1, Neu 1, Neg low

What is the atomic structure made of?

Atomic number, mass number, nucleus, electron cloud

What is the atomic number?

The number of protons

p+

What is the mass number?

Number of protons plus neutrons

p+ plus n

What does the nucleus contain?

Protons and neutrons

p and n

What does the electron cloud contain?

Electron

What are elements determined by?

The atomic number of an atom

Atomic # = # of protons

What are the most basic chemicals?

Elements

What are isotopes?

The specific version of an element based on its mass number

What is atomic weight?

The exact mass of all particles.

Measured in Daltons

What can atomic weight determine for isotopes?

The average mass numbers

AMS

What determines the reactivity of an atom?

Electrons in the electron cloud.

e-

What does the electron cloud contain?

Shells or energy levels that hold a maximum level that hold a maximum number of electrons.

What shells fill first?

The lower shells

What is the outermost shell?

The valence shell

V shell

What does the valence shell determine?

Bonding

What does the number of electrons per shell correspond to?

The number of atoms in that row of the periodic table.

Number in a period

What do chemical bonds involve?

The sharing, gaining, and losing of electrons in the valence shell.

Sharing, gaining, and losing.

What are the three major types of chemical bonds?

Ionic, Covalent, and Hydrogen bonds

H I C

What is an ionic bond?

An attraction between cations (electron donor) and anions (electron acceptor)

Between cats and ans.

What is a covalent bond?

Strong electron bonds involving shared electrons

Strong and shared

What is a hydrogen bond?

Weak polar bonds based on partial electrical attractions.

Weak and partial

What is a molecule?

Two or more atoms joined by strong bonds

2 or more and strong

What is a compound?

Two or more atoms of DIFFERENT ELEMENTS, joined by strong or weak bonds

2 or more and strong or weak

Are all compounds molecules?

Yes, but not all molecules are compounds

H2 = molecule only


H20 = molecule and compound

What three things does an ionic bond consist of?

-One atom (the electron donor) loses one or more electrons and becomes a cation with a positive charge.


-Another atom (the electron acceptor) gains those same electrons and becomes an anion with a negative charge.


-Attraction between opposite charges, then draws the two ions together

One loses, one gains, then attraction

What does a covalent bond consist of?

The sharing of pairs of electrons between atoms.


-One electron is donated by each atom to make the pair of electrons

Shared and donated

What are the types of covalent bonds?

Single Covalent Bond: sharing one pair of electrons


Double Covalent Bond: sharing two pairs of electrons


Triple Covalent Bond: sharing three pairs of electrons

Single, Double, Triple

What does a nonpolar covalent bond involve?

Equal sharing of electrons because atoms involved in the bond have equal pull for the electrons

Equal share, equal pull

What does a Polar covalent bond involve?

The UNEQUAL sharing of electrons because one of the atoms involved has a disproportionately strong pull on the electrons

Unequal and disproportionate pull

What are hydrogen bonds between?

Adjacent molecules, NOT atoms

Molecules, not atoms

What charges are involved in hydrogen bonds?

Slightly positive and slightly negative proportions of polar molecules being attracted to one another

Slightly pos, slightly neg

What causes surface tension?

Hydrogen bonds between water (H2O) molecules

H between H2O

What are the states of matter?

Solid, Liquid, and Gas

S, L, G

Describe solid matter.

Constant volume and shape

Constant v and s

Describe liquid matter.

Constant volume but changes shape

Constant V, changes S

Describe matter in GAS form.

Changes volume AND shape

Changes BOTH

What is the molecular weight of a molecule?

The SUM of the atomic weights of its component atoms

-H = approx 1


-O = approx 16


-H2 = approx 2


-H2O = approx 18

What does a chemical reaction consist of?

Reactants, Products, Metabolism

MRP

What is a reactant?

The materials going into a reaction

Going into

What are products?

The materials that come out of a reaction

Comes out of

What is metabolism?

ALL of the reactions that are occurring at one time

All at once

What is energy (in a chemical reaction)?

The power to do work

Do work!

What is work (in a chemical reaction)?

A change in mass or distance

Change in m or d

What is kinetic energy?

Energy of motion

I like to move it, move it!

What is potential energy?

Stored energy

Keep it safe!

What is chemical energy?

Potential energy stored in chemical bonds

Potent stored in chem bonds

What is a decomposition reaction (catabolism)?

-Breaks chemical bonds


-AB -> A + B


-Hydrolysis: ABCDE + H2O -> ABC-H + HO-DE

Breaks bonds




AB -> A + B

What is a synthesis reaction (anabolism)?

-Forms chemical bonds


-A+B -> AB


-Dehydration synthesis (condensation): ABC-H + HO-DE ->ABCDE + H2O

Forms bonds




A+B -> AB

What is a reversible reaction?

A reaction that occurs simultaneously in both directions



- AB <-> A + B




-At equilibrium the amounts of chemicals do not change even though the reactions are still occurring

Both directions, equilibrium

What reactions seek equilibrium?

Reversible reactions, balancing reaction rates





Add or remove reactions - reaction rates adjust to reach a new equilibrium

What reactions in cell cannot start without help?

Chemical Reactions

Ches

What is activation energy?

The amount of energy needed to get a reaction started

How much do I need to get it moving?

What are enzymes?

Protein catalysts that lower the activation energy of reactants

Prot cats, they lower

What are exergonic (exothermic) reactions?

Produce MORE energy than they use

More than used

What are endergonic (endothermic) reactions?

USE more energy than they produce

Use more than it makes

What are nutrients?

Essential molecules obtained from food

Needed from food

What are metabolites?

Molecules made or broken down in the body

Made or broken in the body

What are inorganic compounds?

-Molecules NOT based on carbon and hydrogen

Carbon dioxide, oxygen, water, and inorganic acids, bases and salts

What are organic compounds?

Molecules based on carbon and hydrogen

Carbs, proteins, lipids, nucleic acids

Up to how much of my body weight is water?

Up to two thirds

What is a solution?

A uniform mixture of TWO OR MORE substances

perfect mix of 2 or more

What does a solution consist of?

-Solvent: a medium that substances are dissolved IN


-Solute: in which atoms, ions, or molecules of another substance ARE dissolved

Solvent and solute

What is solubility?

Waters ability to dissolve a solute in a solvent to make a solution

Solute, in solvent, makes a solution

What is reactivity in water?

Most body chemistry occurs in water

What is high heat capacity in water?

Water's ability to absorb and retain heat

Absorb and retain

What is lubrication?

To moisten and reduce friction

Make it slide

What process do ions and polar compounds undergo in water?

Ionization or dissociation

Ionize or dissociate

What do polar water molecules form around ions and small polar molecules to keep them in solution?

Hydration spheres

Hydrated rounds

What are electrolytes?

Inorganic ions that conduct electricity in solution

Conductive inorganic ions

What does an electrolyte imbalance do in the body?

Disturbs vital body functions

Hurts important functions

What is a hydrophilic compound?

-Interacts WITH water


-Includes ions and polar molecules

Hydro = water


Philos = loving

What is a hydrophobic compounds?

-does NOT interact with water


- includes nonpolar molecules, fats and oils

Hydro = water


Phobic = fear

What is a colloid?

-A solution of very large organic molecules

Blood Plasma

What is suspension?

-a solution in which particles settle (sediment)

Whole blood

What is concentration?

The amount of solute in a solvent

(mol/L, mg/mL)

What is pH?

The concentration of hydrogen ions (H+) in a solutions

Concentration of H+ ions

Describe a neutral pH.

-A balance of H+ and OH

Pure water = 7.0 ph (neutral)

What is the pH of human blood?

Ranges from 7.35 to 7.45

7:35 to 7:45

Describe acidic pH.

-pH lower than 7.0


-HIGH H+ concentration


-LOW OH- concentration

Lemon juice

Describe basic (alkaline) pH.


-pH higher than 7.0


-LOW H+


-HIGH OH-

milk

What does the pH scale have an inverse relationship with?

With H+ concentration

More H+ ions means lower pH, less H+ means higher pH

What is an acid?

-Solute that ADDS hydrogen ions to a solution


-Proton Donor


-Strong acids dissociate completely in solution

P+ donor (makes it pos)

What is a base?

-Solute that REMOVES hydrogen ions from a solution


-Proton acceptor

P+ acceptor (makes it neg)

What are weak acids and weak bases?

-Fail to dissociate completely in solution


-Helps to balance pH

Balances pH

What are salts?

Solutes that dissociate into Cations and Anions, other than hydrogen and hydroxide ions

Except hydrogen and hydroxide ions

Describe an organic molecule.

-Contains H, C, and usually O


-Covalently bonded


-Contains functional groups that determine chemistry (carbs, lipids, protiens (amino acids), nucleic acids

HC and O, covalently bonded

Describe carbohydrates.

-Contains C, H and O; in a 1:2:1 ratio

-Monosaccharides (simple sugar)


-Disaccharides (two sugars)


-Polysaccharides (many sugars)

Describe monosaccharides.

-Simple sugars with 3-7 carbon atoms

Glucose, fructose, galactose

Describe disaccharides.

-Two simple sugars condensed by dehydration synthesis

Sucrose, Maltose

Describe polysaccharides.

-MANY monosaccharides condense by dehydration synthesis

Glycogen, starch, cellulose

What are lipids?

-Mainly hydrophobic molecules (fats, oils, waxes)


-Made mostly of carbon and hydrogen atoms

What do lipids include?

-Fatty acids


-Eicosanoids


-Glycerides


-Steroids


-Phospholipids and glycolipids

PEGS F

What are fatty acids?

-LONG chains of carbon and hydrogen with a carboxylic acid group (COOH) at one end


-Relatively nonpolar, EXCEPT the caboxylic group

-Saturated with hydrogen (no covalent bonds)


-Unsaturated (one or more double bonds) - monounsaturated (1) and polyunsaturated (2+)

Where are eicosanoids derived from?

The fatty acid called arachidonic acid

spider acid

Where are leukotrienes found?

In the immune system

active

What are prostaglandins?

Local hormones


short-chain fatty agains

local, short chain

What are glycerides?

-Fatty acids attached to glycerol molecule

Triglycerides

What are triglycerides?

(triacylglycerolds or neutral fats)


-for energy source


-insulation


-protection

3 important functions



What are steroids?

-Four rings of carbon and hydrogen with an assortment of functional groups

four rings, multiple funct groups

What are the types of steroids?

-Cholesterol (component of plasma cell membranes)


-estrogen and testosterone (sex hormones)


-Corticosteroids and calcitrol (metabolic regulation)


-Bile salts (derived from steroids)

BECC

What are phospholipids and glycolipids?

-Diglycerides attached to either a phosphate group or a sugar


-Both have hydrophilic heads and hydrophobic tails

What are proteins, their basic elements, and basic building blocks?

-Most abundant and important organic molecules


-Basic elements: C, H, O, N


-Building blocks: 20 amino acids

Most abundant and important

What are the functions of proteins?

-Support (structural)


-Movement (contractile)


-Transport (carrier)


-Buffering (regulation of pH)


-Metabolic regulation (enzymes)


-Coordination and control (hormones)


-Defense (antibodies)

What is the protein structure?

-long chains of amino acids

What is the amino acid structure?

-Central carbon atom


-Hydrogen atom


-Amino group (-NH2)


-Carboxylic acid group (-COOH)


-Variable side chain (R group)

What does it require to hook amino acids together?

A dehydration synthesis between:


-The amino group of one amino acid


-and the carboxylic acid group of another amino acid


-Producing a peptide

What are the four shapes of protein?

1. Primary structure


-Sequence of amino acids along a polypeptide


2. Secondary structure


-Hydrogen bonds form spirals of pleats


3. Tertiary structure


-Secondary structure folds into a unique shape


4. Quaternary structure


-Final protein shape


-several tertiary structures together

Primary, Secondary, Tertiary, Quaternary

What are fibrous proteins?

Structural sheets or strands

What are globular proteins?

-Soluble spheres with active functions


-Function is based on shape


-Shape is based on sequence of amino acids

What are enzymes?

Catalysts


-Proteins that lower activation energy of a chemical reaction


-Not changed or used up in reaction

Enzymes are also...

-Specific (only work on limited types of substrates)


-Limited (by their saturation)


-Regulated (by other cellular chemicals)

What are cofactors?

An ion or molecule that binds to an enzyme before substrates can bind

What is a coenzyme?

Nonprotein organic cofactor

vitamins



What are isozymes?

Two enzymes that can catalyze the same reaction

What is denaturation?

Loss of shape and function due to heat or pH

What are glycoproteins?

Large protein + small carb

Enzymes, antibodies, hormones, mucus production

What are proteoglycans?

Large polysaccharides + polypeptides

Promotes viscosity

What are nucleic acids and where are they found?

Large organic molecules, found in the nucleus that store and process info at molecular level

What is DNA and what does it do?

Deoxyribonucleic Acid


-Determines inherited characteristics


-Directs protein synthesis


-Controls enzyme production


-Controls Metabolism

What is RNA and what does it do?

Ribonucleic Acid


-Controls intermediate steps in protein syntheis

-

What is the structure of nucleic acids?

-DNA and RNA are strings of nucleotides

What are nucleotides?

Building blocks of DNA and RNA




Have three molecular parts:


- a sugar


- phosphate group


- nitrogenous base (A, G, T, C, or U)

Is DNA double stranded?

Yes


-the bases form hydrogen bonds to hold DNA together

Can RNA bind to itself?

Sometimes but is usually a single strand

What does DNA form?

A twisting double helix

What are the types of RNA?

Messenger RNA (mRNA)


Transfer RNA (tRNA)


Ribosomal RNA (rRNA)

What is metabolic turnover?

Lets your body grow, change, and adapt to new conditions and activties