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12 Cards in this Set

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What are these zones in liver called as?

Rappaport zones

What is the arrangement of Rappaport zones in liver histology?

123 from periphery to central vein

Causes of predominat injury to Rapport zone 1

veyi l


Viral hepatitis


Eclampsia


yellow phosphorous


Iron


@ Zone l

Causes of injury to zone 2 in liver histology

BYe 2



Beryllium


Yellow fever 🤒

Causes of injury to zone 3 of liver

CHAP 3



Chloroform


Halothane / Ccl4


Alcohol


Paracetamol

Transaminitis where AST = ALT


ie., AST : ALT is 1

Ischemic Hepatitis



(1 = I)

Conditions where AST is less than ALT


ie., AST:ALT < 1

Less PVT NA


Paracetamol posoining


Viral hepatitis


Toxic hepatitis


NA fatty liver disease



(ALT is liver specific, so these above things cause liver injury and so ALT raise)

Conditions causing AST increased twice that of ALT

Alcoholoic hepatitis

In alcoholics, what is AST : ALT > 2 called as

de Ritis ratio

Normogram in para poisoning

Prescott or Rumack Mathew normogram

Applicable only in single dose toxicity in Normal person with Normal LFT

Bext time to start NAC in para poisoning

Within 8 hours

Contra indications of IFN alpha therapy

Autoimmune disease


Pregnancy


Psychiatric disorder


Seizure


Cirrhosis


CHF


Cytopenia