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50 Cards in this Set

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  • Back
What is Heart Failure?
Heart Failure is a condition in which the heart can't pump enough blood throughout the body

As a result, vital organs such as the brain, liver and kidneys are affected
What are the leading causes of Heart Failure?
1) Coronary Artery Disease
2) Hypertension
3) Diabetes
(High levels of lipid in the blood= atherosclerosis & hypertension)
What is Cardiomyopathy?
Damage to the heart muscle
Pathophysiology of heart failure
See chart
The Renin-Angiotensin-Aldosterone System (RAAS) in heart failure
See chart
How does the Heart compensate?
1) The heart muscle thickens to compensate for increased volume: Ventricular hypertrophy

2) It may enlarge, which allows more blood into the heart: Ventricular dilatation

3) It may contract more frequently to increase circulation

4) Activation of kidney's neurohormonal sytem: salt & water retention
Symptoms?
1) The heart's inability to pump blood and supply oxygen to organs
2) Congestion of the lungs with extra fluid
3)Lungs
- Dyspnea
- Orthopnea: Cant sleep at night
What is Acute Heart Failure Syndrome? (AHFS)
Is defined as gradual or rapid change in Heart Failure signs & symptoms resulting in a need for urgent therapyé
What are the precipitating factors?
- Concurrent cardiovascular conditions (CHD, Hypertension,)
- Diabetes
- Anemia
What are the symptoms?
- Sudden fluid build-up
- Rapid irregular heartbeat with palpitations that may cause the heart to stop beating
- Sudden , severe shortness of breath and coughing up pink, foamy mucus
- Chest pain if caused by MI
Part of the heart affected by heart failure
See Chart
What are the Stages of Heart Failure Classification from NYHA (New York Heart Association)
See Chart
What is the newer classification system?
American College of Cardiology Scale
(Uses letters A to D)

Stage A; A person who has several risk factors for heart failure

Stage D: A person with end-stage heart failure
How is it diagnosed?
1. History
2. Examination
3. Investigations
a- Blood tests: check kidneys and thyroid function
b- Specific chemical markers of heart failure: Brain Natriuretic peptide (BNP)
Diagnose continued
4. Chest X-Ray to check:
a- Condition of the lungs
b- Size of the heart

5. ECG
a- Heart rhythms problems
b- Size of the heart

6. Echocardiogram
- It helps determine the Ejection fraction

7. Strest test
8. Cardiac CT or MRI scans
9. Coronary catherization (Angiogram)
How is is treated?
1. ACE Inhibitors
2. Diuretics
3. Vasodilators
4. Digitalis preparations
5. Beta Blockers
6. Blood thinners
7. Angiotensin II Receptor Blockers
8. Calcium Channel Blockers
9. Cholesterol-Lowering Drugs
How does Coronary Artery disease produce heart failure?
The arteries become narrow or clogged, limiting blood supply to the heart
How does Hypertension produce heart failure?
Increased Blood Pressure causes the heart to overworked.
How does Heart valve or Congenital heart defects produce heart failure?
Increase volume or increase pressure leads to obstruction
How does Arrhythmias produce heart failure?
Abnormal heart rhythm causes heart to overwork
Explain how Coronary artery disease produce heart failure?
The arteries become narrowed or clogged, limiting blood supply to the heart
Explain how hypertension produce heart failure?
Increased BP causes the heart to go into tachycardia. Heart compensates too much (over works)
Explain how Heart valve disease or Congenital heart defects produce heart failure?
Increase volume or increase pressure leads to obstruction
Explain how arrhythmias produce heart failure?
Abnormal heart rhythm causes heart to overwork
Explain how Diabetes produce heart failure?
Increased lipids levels in the blood causes atherosclerosis and hypertension
What are the symptoms of heart failure?
Myocardial Infarction
Edema of lower limbs
Dyspnea
What are the signs of Heart Failure?
Sudden fluid build-up
Swollen or tender abdomen
Sudden weight gain
Why is there dyspnea with heart failure?
Increased pressure and/or extra fluid in the lungs
Why is there oedema with heart failure?
Systemic circuit can't return to heart, so it builds up in the legs (venous congestion)
Why is there lack of appetite with heart failure?
Due to a build up of fluid (congestion) around the liver & gut interfering with digestion
What is Brain natriuretic peptide?
It is a chemical marker that is secreted by the heart at high levels when it's injured or overworked
Cite 3 medications used to treat heart failure?
1) Beta-Blockers
2) ACE inhibitors
3) Diuretics
What is the drug of choice to treat heart failure?
ACE inhibitors (Cardura)
Why are ACE inhibitors useful in heart failure?
Dilate the blood vessels so blood can flow through more easily. ( lower BP= blocks the conversion of Angiotensin I into Angiotensin II)
Cite 3 side effects of ACE inhibitors?
1) Persistent cough
2) Weakness & dizziness
3) Altered sense of taste
What category of medications do Lasix and Butamex belong to?
Diuretics
What is their mechanism of action?
Help eliminate the extra water & sodium salt that causes swelling of the ankles, and shortness of breath
Cite an important precaution with the use of such drugs?
Important to eat food high in potassium because diuretics may cause loss of potassium
Name a potassium sparing diuretic?
Aldactone
Why does a patient not need to take K+ supplements with Aldactione?
Aldactone acts as an aldosterone antagonist meaning Na loss and K+ retention
Cite a vasodilator?
Apresoline
What is their mechanism of action?
Relaxes smooth muscles & widens blood vessels
How do vasodilators produce "orthostatic hypotension"?
Because vasodilators dilates arterioles & veins (abolish constriction)
How does Digoxin (Lanoxin) improve the symptoms of heart failure?
It increases the force of heart muscular and increases the COP. It also helps avoid rapid heart rhythms.
Cite 2 precautions with the use of Lanoxin?
1) Predispose to some arrhythmias
2) Hypokalcimia
Cite the advantage of administering a Beta blocker to a person suffering from heart failure?
The failing heart tries to compensate for its weakened pumping action by beating faster, which puts more strain on it. Beta blockers reduce the heart's tendency to beat faster
Cite the name of two Angiotensin II receptor blockers?
1) Micardis
2) Diovan
Cite 2 side effects of these medications?
Cough
High level of potassium
What are the dual effects of Calcium channel blockers on heart failure?
Lower BP
Increase Coronary blood flow
Cite 3 side effects of calcium channel blockers?
1) Headache
2) Dizziness
3) Drowsiness