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16 Cards in this Set

  • Front
  • Back
What is most common cause of heart
failure?
Ischemic cardiomyopathy in industrialized countries, in others, infectious diseases.
What are the risks for heart failure?
HTN, DM, cardiotoxic substance use (smoking, cocaine, chemos s.a. anthracycline, trastuzumab), HLD, thyroid Dz, tachycarida, CAD
What are some symptoms and signs for heart failure?
dyspnea, fatigue, exercise-intolerance, fluid retention, SOB
What tests should you get in evaluating heart failure?
ACC/AHA recommends, EKG, Echo, exercise testing, cardiac cath, endomyocardial bx, BNP, TSH. CXR
What are the types of heart failure?
Systolic heart failure
Diastolic heart failure
What is the distinction between systolic and diastolic heart failure?
In systolic heart failure, the EF < 50%.
In diastolic heart failure, the EF is normal.
How should you evaluate functional capacity in patients with heart failure?
Use the NYHA, 6 min walk test.
What is the NYHA?
Functional classification of heart failure.
class I; asymptomatic with normal activity.
class II; fatigue, SOB with normal activity.
class III; symptomatic with minimal activity.
class IV; symptomatic at rest.
What dietary restriction in the management of heart failure?
Despite paucity of evidence, the ACC/AHA, sodium restriction < 2gm
and fluid < 2 quarts per day.
What pharmacotherapies use for tx of heart failure?
ACEi,(ARB in pt intolerable of SE of ACEi) Endpoint is SBP to 90mm Hg

BB, who are stable on ACEi. (multiple studies to back this up, CAPRICORN, COPERNICUS studies)
What med you use if pt is intolerant of ACEi or BB?
Use Hydralazine and long acting Nitrates.

In AA who are symptomatic, use it in combination with ACEi or ARB increased survival. (The A-HeFT trial)
When is Aldosterone Antagonists appropriate for heart failure?
NYHA class III to IV despite ACEi and BB. (The Randomized Aldosterone Evaluation Study). Eplenerone is newer, more selective aldosterone antagonist with fewer SE.

Combo of ACEi/ARB and spiroondactone should be avoided d/t increased risk of hyperK+
What is the role of loop diuretics in heart failure?
Use in combination with Low sodium diet to control volume overload, maintain stable wt and improve functional capacity. NEVER be use alone in patient with heart failure.
What is the role of digoxin in heart failure?
Digoxin can alleviate symptoms and decrease hospitalization. No survival difference when compared to placebo.
What are the treatment goals for diastolic heart failure?
control
1. HR to allow adequate filling
2. SR
3. control volume to decrease diastolic pressure
4, control BP
5, minimized ischemia
When is an intracardiac device (ICD) indicated in heart failure?
patients with EF of <30% in NYHA I, II, or III and an overall life expectancy of > 6 months.

Class IV do no benefit from ICD placement. (DEFINITE study)