Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
12 Cards in this Set
- Front
- Back
|
site of control of appetite in brain
|
arcuate nucleus
synthesize & rls peptides integrate info from periphery |
|
|
grhelin
|
from intestine
stimulates appetite increases NPY in brain upregulated when on diet rmv stomach, have less prader willi |
|
|
CCK
|
from intestine
signals satiety short term reg |
|
|
GLP 1
|
from intestine
signals satiety short term regulation released in proportion to amount of food decreased in obese people |
|
|
PYY
|
from intestine
signals satiety- suppress ghrelin (15 min into meal) co-secreted w/GLP 1 short term regulation |
|
|
short term regulators of satiety
|
CCK
GLP 1 PYY no effect on adiposity directs meal termination |
|
|
long term regulation
|
leptin
adponectin insulin NPY regulates energy homeostasis |
|
|
leptin
|
fat cells
R's in hypothal decreased Fat store to decrese leptin, increase appetite & metabolism leptin stimulates AMPK (obese ppl with higher levels) protect against wt loss during starvation |
|
|
Insulin
|
levels proportional to adipose tissues
R's saturable direct inject to brain lose weight |
|
|
Adiponectin
|
inhibit glucose synth in liver
(use more, store less) |
|
|
NPY
|
gives signal to eat
decreases with increased leptin & insulin |
|
|
POMC
|
proopiomelanocortins
family limited to acruate nucleus alpha MSH binds R to signal for reduced food intake rats w/R defic are obese |
