Genomics And Proteomics

Front 1

Genomics

Back 1

The analysis of entire genomes

Front 2

Proteomics

Back 2

The analysis of all proteins

Front 3

Transcriptome Analysis

Back 3

The study of all expressed genes

Front 4

Metagenomics

Back 4

Sequence genomes of microbe communities in environmental samples

Front 5

Systems Biology

Back 5

Integration of genomics, transcriptome analysis and proteomics

Front 6

Clone-By-Clone Approach

Back 6

During clone-by-clone sequencing, a map of each chromosome of the genome is made before the DNA is split up into fragments ready for sequencing

Front 7

Contigs

Back 7

A set of overlapping DNA segments that together represent a consensus region of DNA

Front 8

Cosmic

Back 8

Plasmid vector that contains a lambda phage cos sequence

Front 9

Annotation

Back 9

Process of identifying gem-regulatory sequences and other sequences of interest in the genome so that gene maps can be developed

Front 10

What does BLAST stand for?

Back 10

Basic Local Alignment Search Tool

Front 11

E Value

Back 11

- Tells you how significant the match is

- The smaller the number, the more significant the match

- The number of matches you would expect by chance

Front 12

Functional Genomics

Back 12

The study of gene functions based on the resulting RNAs or possible proteins they encode, and the functions of other components of the genome, such as gene-regulatory elements

Front 13

Putative Genes

Back 13

A segment of DNA whose protein, and its function, is not known, but based on its open reading frame, it is believed to be a gene

Front 14

Pseudo Genes

Back 14

Look exactly like genes but are never found expressed as RNA

Front 15

Protein Domains

Back 15

- A conserved part of a given protein sequence (tertiary structure) that can evolve, function, and exist independently of the rest of the protein chain

- (e.g., ion channels, secretion and export signals)

Front 16

ChIP

Back 16

- Chromatin Immunoprecipitation

- Maps protein-DNA interactions

- Useful for identifying genes that are regulated by DNA-binding transcription factors

Front 17

Microsattelites

Back 17

Sequences that repeat over and over and over

Front 18

Comparative Genomics

Back 18

Comparing genomes of different organisms

Front 19

Transcriptome Analysis

Back 19

Asks which genes are expressed? (qualitative) And how much of each gene is expressed? (quantitative)