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30 Cards in this Set
- Front
- Back
deCODE (biotechnology company)
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creating database that contains health, geological, and genetic information of approx. 270 000 residents of Iceland
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basic subunits of which DNA is composed of
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nucleotides
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largest category of proteins
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enzymes
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characteristics of model organisms
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availability of mutant strain
easy growth and maintenance short reproductive cycle many offspring per female |
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fundamental property of DNA's nitrogenous bases necessary for double-stranded nature of its structure
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complementarity
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class of enzymes that cut DNA at specific nucleotide sequences
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restriction enzymes
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alternative forms of a gene
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alleles
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collective name of various characteristics of organisms that result from genetic makeup
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phenotype
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organisms that are well understood from scientific standpoint and used in basic biological research
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model organisms
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features of DNA that suit it for its role as hereditary molecule
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able to replicate
informational content stability while still able to mutate/change |
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bivalents formed during meiosis of organisms with 2n chromosomes
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n
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n primary spermatocytes
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2n secondary spermatocytes, 4n sperm cells
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n primary oocytes
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n secondary oocytes, n first polar bodies
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n units of DNA in G1 - how much during metaphase I?
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2n
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side-by-side alignment of homologous chromosomes
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synapsis
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homologous chromosomes have in common
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same length, placement of centromere, bonding pattern, autoradiographic pattern, code for same gene
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mitosis: phases
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prophase
metaphase anaphase telophase |
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mitosis: checkpoints
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G1/S
G2/M M |
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checkpoint: G1/S
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monitors size of cell, condition of DNA - if cell size is not normal or DNA is damaged, cell cycle stops until fixed
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checkpoint: G2/M
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if replication is incomplete or DNA is damaged, cycle is arrested
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checkpoint: M
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monitors formation of spindle fiber and attachment of fibers to kinetochore - if improperly formed or inadequately attached, mitosis arrested
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meiosis: stages of prophase I
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leptonema
zygonema pachynema diplonema diakinesis |
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centromere location: metacentric
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middle
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centromere location: submetacentric
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between middle and end
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centromere location: acrocentric
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close to end
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centromere location: telocentric
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at end
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Mendel's postulates
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1. unit factors in pairs
2. dominance/recessiveness 3. segregation 4. independent assortment |
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continuous variation
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offspring are blend of parents' phenotypes
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discontinuous variation
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dominance-recessive relationship between units
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chromosomal theory of inheritance
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genetic material in living organisms is contained in chromosomes
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