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30 Cards in this Set

  • Front
  • Back
deCODE (biotechnology company)
creating database that contains health, geological, and genetic information of approx. 270 000 residents of Iceland
basic subunits of which DNA is composed of
nucleotides
largest category of proteins
enzymes
characteristics of model organisms
availability of mutant strain
easy growth and maintenance
short reproductive cycle
many offspring per female
fundamental property of DNA's nitrogenous bases necessary for double-stranded nature of its structure
complementarity
class of enzymes that cut DNA at specific nucleotide sequences
restriction enzymes
alternative forms of a gene
alleles
collective name of various characteristics of organisms that result from genetic makeup
phenotype
organisms that are well understood from scientific standpoint and used in basic biological research
model organisms
features of DNA that suit it for its role as hereditary molecule
able to replicate
informational content
stability while still able to mutate/change
bivalents formed during meiosis of organisms with 2n chromosomes
n
n primary spermatocytes
2n secondary spermatocytes, 4n sperm cells
n primary oocytes
n secondary oocytes, n first polar bodies
n units of DNA in G1 - how much during metaphase I?
2n
side-by-side alignment of homologous chromosomes
synapsis
homologous chromosomes have in common
same length, placement of centromere, bonding pattern, autoradiographic pattern, code for same gene
mitosis: phases
prophase
metaphase
anaphase
telophase
mitosis: checkpoints
G1/S
G2/M
M
checkpoint: G1/S
monitors size of cell, condition of DNA - if cell size is not normal or DNA is damaged, cell cycle stops until fixed
checkpoint: G2/M
if replication is incomplete or DNA is damaged, cycle is arrested
checkpoint: M
monitors formation of spindle fiber and attachment of fibers to kinetochore - if improperly formed or inadequately attached, mitosis arrested
meiosis: stages of prophase I
leptonema
zygonema
pachynema
diplonema
diakinesis
centromere location: metacentric
middle
centromere location: submetacentric
between middle and end
centromere location: acrocentric
close to end
centromere location: telocentric
at end
Mendel's postulates
1. unit factors in pairs
2. dominance/recessiveness
3. segregation
4. independent assortment
continuous variation
offspring are blend of parents' phenotypes
discontinuous variation
dominance-recessive relationship between units
chromosomal theory of inheritance
genetic material in living organisms is contained in chromosomes