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6 Cards in this Set

  • Front
  • Back
Frederick Griffith
S-strain bacteria could transform R-strain bacteria to kill a mice. (1928)
Oswald T. Avery
Isolated "transforming principle" from S-strain using alcohol precipitation. Determined that just the transforming principle along with R-Bacteria was sufficient for transformation. (1931)
Colin Macleod and Maclyn McCarty
Determined transforming principle was DNA. Achieved by fractionating the transforming principle and determined which macromolecule was responsible for transformation. (1944)
Alfred Hershey and Martha Chase
DNA is the molecule responsible for viral replication. Worked with bacteriophages and radio-labeled proteins. Location of labeled components was the key point here! Sulfur only found in some amino acid r groups and Phosphorus only found in DNA and not Proteins. (1952)
Watson and Crick
Determined 3-D structure of DNA. (1953)
Meselson and Stahl
Confirmed semiconservative replication using heavier density Nitrogen and lighter density nitrogen in bacterial DNA replication.
(1958)