Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
29 Cards in this Set
- Front
- Back
Warts. Soft, tan-colored, cauliflower-like lesions.
Epidermal hyperplasia, hyperkeratosis, koilocytosis. |
verrucae
verruca vulgaris (hands) condyloma acuminatum (genitals via HPV) |
|
common mole. benign.
|
nevocellular nevus
|
|
hives. intensely pruritic wheals that form after mast cell degranulation.
|
urticaria
|
|
freckle. norm number of melanocytes, increased melanin pigment.
|
ephelis
|
|
pruritic eruption, common on skin flexures.
associated with asthma, allergic rhinitis |
atopic dermatitis (eczema)
|
|
papules and plaques with silvery scaling
esp on knees/elbows acanthosis with parakeratotic scaling. increased stratum spinosum, decreased stratum granulosum. |
psoriasis
Auspitz sign (bleeding spots where scales scraped off) nail pitting and psoriatic arthritis assoc |
|
flat, greasy, pigmented squamous epith proliferation with keratin-filled cysts (horn cysts).
looks "pasted on" head, trunk, extremities |
seborrheic keratosis
common benign neoplasm of older persons |
|
normal melanocyte number with decreased melanin production (decreased tyrosinase activity)
also failure neural crest cell migration |
albinism
|
|
irregular areas complete depigmentation.
decrease in melanocytes |
vitiligo
|
|
hyperpigmentation assoc pregnancy
|
melasma
"mask of pregnancy" or OCP use |
|
superficial skin infection from S. aureus or S. pyogenes
highly contagious, honey-colored crusting |
impetigo
|
|
acute, painful spreading infection of dermis/subcut tissues
S. aureus or S. pyogenes |
cellulitis
|
|
anaerobic bacteria and S. pyogenes (deeper tissue injury)
crepitus from methane and CO2 production |
necrotizing fasciitis
"flesh eating bacteria" |
|
exotoxin destroys keratinocyte attachments in stratum granulosum ONLY
|
staphylococcal scalded skin syndrome (SSSS)
fever and gen erythematous rash with sloughing of upper layers of epidermis (newborns and children) |
|
white, painless plaques on tongue, cannot be scraped off
|
hairy leukoplakia
EBV mediated. relatively specific for HIV |
|
potentially fatal autoimmune disorder
IgG antibody against desmosomes (anti-epithelial) |
pemphigus vulgaris
IF throughout epidermis acantholysis (intraepidermal bullae involving skin/oral mucosa) positive Nikolsky's sign |
|
autoimmune disorder
IgG against hemidesmosomes |
bullous pemphigoid
linear IF. Eosinophils within blisters less severe than pemphigus vulgaris Negative Nikolsky's sign |
|
pruritic papules and vesicles
deposits IgA at tips dermal papillae |
dermatitis herpetiformis
assoc with celiac disease |
|
infections (Mycoplasma, HSV), drugs, cancers, autoimmune disease
multiple types lesions |
erythema multiforme
macules, papules, vesicles, target lesions |
|
fever, bulla formation/necrosis, sloughing skin, high mortality rate
|
stevens-johnson syndrome
associ with adverse drug reaction |
|
more severe of Stevens-Johnson syndrome
greater epidermal involvement |
toxic epidermal necrolysis
|
|
pruritic, purple, polygonal papules
sawtooth infiltrate of lymphocytes at dermal-epidermal junction |
lichen planus
assoc with hepatitis C |
|
premalignant lesions caused by sun exposure
|
actinic keratosis
small, rough, erythematous or brownish papules "cutaneous horn" |
|
hyperplasia stratum spinosum
|
acanthosis nigricans
associ with hyperlipidemia (Cushing's disease, DM), visceral malignancy |
|
inflamm lesion subcut fat (anterior shins)
|
erythema nodosum
coccidioidomycosis, histoplasmosis, TB, leprosy, strep infection, sarcoidosis |
|
"herald patch" followed days later by "christmas tree" distribution
|
pityriasis rosea
multiple papular eruptions, remits spontaneously |
|
excessive exposure sunlight/arsenic exposure
appears on hands/face; invasive locally but rare met |
squamous cell carcinoma
associ chronic draining sinuses "keratin pearls"; actinic keratosis is precursor |
|
sun exposed areas of body
rolled edges with central ulceration; "pearly" papules |
basal cell carcinoma
"palisading" nuclei |
|
tumor with sig risk metastasis
sunlight exposure S-100 marker |
melanoma
fair skinned ppl increased risk dysplastic nevus precursor (dark, irregular borders) depth of tumor correlates with risk met |