First Aid Derm Skin Disorders

Front 1

Warts. Soft, tan-colored, cauliflower-like lesions.

Epidermal hyperplasia, hyperkeratosis, koilocytosis.

Back 1

verrucae

verruca vulgaris (hands)
condyloma acuminatum (genitals via HPV)

Front 2

common mole. benign.

Back 2

nevocellular nevus

Front 3

hives. intensely pruritic wheals that form after mast cell degranulation.

Back 3

urticaria

Front 4

freckle. norm number of melanocytes, increased melanin pigment.

Back 4

ephelis

Front 5

pruritic eruption, common on skin flexures.

associated with asthma, allergic rhinitis

Back 5

atopic dermatitis (eczema)

Front 6

papules and plaques with silvery scaling

esp on knees/elbows

acanthosis with parakeratotic scaling. increased stratum spinosum, decreased stratum granulosum.

Back 6

psoriasis

Auspitz sign (bleeding spots where scales scraped off)

nail pitting and psoriatic arthritis assoc

Front 7

flat, greasy, pigmented squamous epith proliferation with keratin-filled cysts (horn cysts).

looks "pasted on"

head, trunk, extremities

Back 7

seborrheic keratosis

common benign neoplasm of older persons

Front 8

normal melanocyte number with decreased melanin production (decreased tyrosinase activity)

also failure neural crest cell migration

Back 8

albinism

Front 9

irregular areas complete depigmentation.

decrease in melanocytes

Back 9

vitiligo

Front 10

hyperpigmentation assoc pregnancy

Back 10

melasma

"mask of pregnancy" or OCP use

Front 11

superficial skin infection from S. aureus or S. pyogenes

highly contagious, honey-colored crusting

Back 11

impetigo

Front 12

acute, painful spreading infection of dermis/subcut tissues

S. aureus or S. pyogenes

Back 12

cellulitis

Front 13

anaerobic bacteria and S. pyogenes (deeper tissue injury)

crepitus from methane and CO2 production

Back 13

necrotizing fasciitis

"flesh eating bacteria"

Front 14

exotoxin destroys keratinocyte attachments in stratum granulosum ONLY

Back 14

staphylococcal scalded skin syndrome (SSSS)

fever and gen erythematous rash with sloughing of upper layers of epidermis (newborns and children)

Front 15

white, painless plaques on tongue, cannot be scraped off

Back 15

hairy leukoplakia

EBV mediated. relatively specific for HIV

Front 16

potentially fatal autoimmune disorder

IgG antibody against desmosomes (anti-epithelial)

Back 16

pemphigus vulgaris

IF throughout epidermis

acantholysis (intraepidermal bullae involving skin/oral mucosa)

positive Nikolsky's sign

Front 17

autoimmune disorder

IgG against hemidesmosomes

Back 17

bullous pemphigoid

linear IF. Eosinophils within blisters

less severe than pemphigus vulgaris

Negative Nikolsky's sign

Front 18

pruritic papules and vesicles

deposits IgA at tips dermal papillae

Back 18

dermatitis herpetiformis

assoc with celiac disease

Front 19

infections (Mycoplasma, HSV), drugs, cancers, autoimmune disease

multiple types lesions

Back 19

erythema multiforme

macules, papules, vesicles, target lesions

Front 20

fever, bulla formation/necrosis, sloughing skin, high mortality rate

Back 20

stevens-johnson syndrome

associ with adverse drug reaction

Front 21

more severe of Stevens-Johnson syndrome

greater epidermal involvement

Back 21

toxic epidermal necrolysis

Front 22

pruritic, purple, polygonal papules

sawtooth infiltrate of lymphocytes at dermal-epidermal junction

Back 22

lichen planus

assoc with hepatitis C

Front 23

premalignant lesions caused by sun exposure

Back 23

actinic keratosis

small, rough, erythematous or brownish papules

"cutaneous horn"

Front 24

hyperplasia stratum spinosum

Back 24

acanthosis nigricans

associ with hyperlipidemia (Cushing's disease, DM), visceral malignancy

Front 25

inflamm lesion subcut fat (anterior shins)

Back 25

erythema nodosum

coccidioidomycosis, histoplasmosis, TB, leprosy, strep infection, sarcoidosis

Front 26

"herald patch" followed days later by "christmas tree" distribution

Back 26

pityriasis rosea

multiple papular eruptions, remits spontaneously

Front 27

excessive exposure sunlight/arsenic exposure

appears on hands/face; invasive locally but rare met

Back 27

squamous cell carcinoma

associ chronic draining sinuses

"keratin pearls"; actinic keratosis is precursor

Front 28

sun exposed areas of body

rolled edges with central ulceration; "pearly" papules

Back 28

basal cell carcinoma

"palisading" nuclei

Front 29

tumor with sig risk metastasis
sunlight exposure

S-100 marker

Back 29

melanoma

fair skinned ppl increased risk

dysplastic nevus precursor (dark, irregular borders)
depth of tumor correlates with risk met