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35 Cards in this Set

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Influenza
Orthomyxoviridae virus causes what viral disease of the lower respiratory system?
H spikes
Hemmagglutinin
Binds to host cells
N spikes
Neuraminidase
Assist in viral budding and release
Antigenic variation
Major outbreaks associated with the development of new strains of the virus. New strains result from mutation and reassortment.
Type A
Every 2-4 years
Most pandemics
What type of antigenic variation is this?
Type B
What type of antigenic variation is this?

Every 4-6 years
Geographically limited
Type C
What type of antigenic variation is this?

Only sporadic cases
Antigenic drift
Minor mutations in the genes that code for the H and N spikes.
Antigenic shift
Reassortment of RNA from different strains.
Influenza
overall chills
fever
headache
Malaise
Cough

Pneumonia
Reyes Syndrome
High fever
protracted vomiting
liver and brain damage -> coma and death.
Respiratory droplets
indirect contact
How is influenza transmitted?
vaccine
How could influenza be prevented?
Histoplasmosis
Name the disease that is caused by Histoplasma.
Darling's Disease
What is the common name of Histoplasmosis?
Histoplasma
Name the genus that causes Histoplasmosis.
Coccidiomycosis
What is the name of the disease that has a common name of San Jaquin Valley Fever?
Coccidioides
Name the genus that causes Coccidioidomycosis.
Coccidiodomycosis
Name the disease that is caused by the organism, Coccidioides.
Inhalation of spores
How is Coccidiomycosis transmitted?
Pneumocystis Pneumonia
PCP

Multiply in the alveoli -> fills the air spaces -> Often fatal in AIDS patients.
Pneumoncystis
Name the genus that causes Pneumocystis Pneumonia.
Droplet route
inhalation
How is Pneumocystis Pneumonia transmitted?
Blastomycosis
Name the disease that is caused by the genus, Blastomyces.
Blastomyces
Name the genus that causes the disease Blastomycosis.
Fungus
What type of organism causes the disease, Blastomycosis?
fungi
What type of organism causes the disease, Coccidiodomycosis?
fungi
What type of organism causes the disease, Histoplasmosis?
Blastomycosis
Symptoms:

Most asmyptomatic
Chronic skin disease
System disease may involve an organ or CNS 30-60 deaths/year.

Name disease.
Inhalation of spores or through cuts
How is Blastomycosis transmitted?
Aspergillosis
What disease is caused by the organism, Aspergillus?
Aspergillus
Name the organism or genus that caused the disease, Aspergillosis?
Aspergillosis
Continues to grow in a mold form within the body.

Forms Aspergillomas (Ball of mycelium) in the lungs.
Systemic: B.V. -> Thrombosis -> seizures

Name disease.
fungi`
What type of organism is Aspergillus?
Aspergillosis
Sym: flu-like symptoms
Chest pain
Headache
Chills

Complications:
Ulceration of: Tongue, palate and larynx. Meningitis, end and pericarditis.

Trans: Inhalation of spores
Inhalation of spores
How is Aspergillosis transmitted?