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198 Cards in this Set

  • Front
  • Back
What are the 7 characteristics of living organisms?



Cellular Organization


Ordered Complexity


Sensitivity


Growth, Development, and Reproduction


Energy Utilization


Homeostasis


Evolutionary Adaption

What is the hierarchal organization of living organisms?

Cellular level


Organismal level


Population level


Ecosystem level


Biosphere

What makes up the cellular level of the hierarchal organization of living organisms?


Atoms, molecules, organelles, cells


Cell is the basic unit of life

What makes up the organismal level of the hierarchal organization of living organisms?
Tissue, organ, organ system, organism
What makes up the population level of the hierarchal organization of living organisms?
Population, species, community
What are the steps of the scientific process?

Observation


Hypothesis formation


Prediction


Experimentation


Conclusion

What is deductive reasoning?


Sometimes called the "from the top down" approach


Theory> Hypothesis> Observation> Confirmation

What is inductive reasoning?


Sometimes called the "from the bottom up" approach


Observation> Pattern> Tentative Hypothesis> Theory

What is a hypothesis?

A possible explanation for an observation
Why must a hypothesis be tested?

To determine its validity

Why is a hypothesis tested in many different ways?

To determined its validity, and to allow for predictions to be made
What is a iterative?

A hypothesis can be changed and refined with new data
What are the unifying themes of biology?

Cell Theory


Molecular Basis of Inheritance


Structure and Function


Diversity of Life Arises by Evolution


Evolutionary Conservation


Cells are Information-Processing Systems


Nonequilibrium State

What is cell theory?


All organisms are composed of cells


Cells are life's basic units


All cells come from preexisting cells

What is the molecular basis of inheritance?


Deoxyribonucleic acid (DNA)


Sequence of 4 nucleotides encode cells information


Gene


Genome


Continuity of life depends on faithful copying of DNA into daughter cells

What is a gene?

A discrete unit of information

What is a genome?

An entire set of DNA instructions
What is structure and function?


Study structure to learn function


Knowing a function- look for that structure in other organisms

What is an example of structure and function?

Red blood cells have no nucleus


-Carry more hemoglobin


>Bind more oxygen


-Concave shape = increased surface area

What does it mean that "diversity of life arises by evolution"


Underlying unity of biochemistry and genetics argues for life from the same origin event


Diversity due to evolutionary change over time


3 Domains

What are the 3 domains of diversity of life that arise by evolution?


Bacteria: single-celled prokaryote


Archaea: single celled- prokaryote


Eukarya: single-celled or multicellular eukaryote

What are four types of Eukarya?

Plantae, fungi, animalia, and protista
What is evolutionary conservation?


All organisms today descended form a simple creature 3.5 BYA


Some characteristics preserved -use of DNA


Conservation reflects that they have a fundamental role

What does it mean that cells are information-processing systems?


Information in DNA used to direct synthesis of cellular components


-Control of gene expression leads to different cell/tissue types


Cells process environmental information


-Glucose levels, presence of hormones


Cells in multicellular organisms must coordinate with each other

What is a nonequilibrium state?


Living systems are open systems


-Constantly exchange matter and energy with surroundings


Constant supply of energy needed


Self-organizing properties at different levels


Emergent properties from collections of molecules, cells, and individuals

What evidence supports Darwin's discoveries?


Homology/Analogy


Molecular Evidence


Vestigial Structure

What is homology?
Same evolutionary origin but now differ in structure and function
What is comparative anatomy?
Vertebrate forelimbs all share the same basic array of bones
What is analogy?

Structures of different origin used for same purpose with no evolutionary link (butterfly and bird wings)
What is molecular evidence?


Compare genomes or proteins of different organisms


Phylogenetic trees

What are phylogenetic trees?

Based on tracing origin of particular nucleotide changes to reconstruct an evolutionary history
What are vestigial structures?
A structure in an organism that has lost all or most of its original function in the course of evolution.
What are atoms composed of?


Protons


Neutrons


Electrons

What are protons?


Positively charged ions located in the atoms nucleus


What are neutrons?

Neutral particles located in the nucleus
What are electrons?

Negatively charged particles found in orbitals surrounding the nucleus
All matter is composed of?

Atoms
How is atomic number determined?


Number of protons equals number of electrons


-Atoms are electrically neutral


Atomic number = number of protons


-Every atom of a particular element has the same number of protons

What is an element?

Any substance that cannot be broken down to any other substance by ordinary chemical means
What is atomic mass?

Refers to amount of substance

What is atomic weight?

Refers to force gravity exerts on sunstance

How is atomic mass determined?

Sum of protons & neutrons is the atom's atomic mass
What are electrons?


Negatively charged particles located in orbitals

Neutral atoms have the same number of what?

Electrons and protons

What are ions?

Charged particles - unbalanced

What is a cation?

More protons than electrons

What charge does a cation have?

Positive

What is an anion?

Fewer protons than electrons

What charge does an anion have?


Negative
What are enegry levels?

Rings in which electrons are found

Most atoms are stable with how many electrons on their outer shell?

8

How many electrons fill the inner most shell?

2
Positive oxidation numbers form what?

Cations

Negative oxidation numbers form what?

Anions

Oxidation numbers are based on what?

Number of electrons in outer shell
What are isotopes?

Atoms of a single element that possess different numbers of neutrons

What are radioactive isotopes?

Unstable and emit radiation as the nucleus breaks up

What is considered the half like of the isotope?


Time it takes one-half of the atoms in a sample to decay
What is iodine - 131 used for?


Detection and treatment of thyroid treatment


Thyroid filters the iodide and a probe can be used to measure the gamma radiation

What is Colbolt - 60 used for?

Effective at treating cancers


Releases gamma rays

Where does the key to the chemical behavior of an atom lie?
In the number and arrangement of its electrons in their orbitals

What is the Bohr model?

Electrons in discrete orbits

How does modern physics define orbitals?


Area around a nucleus where an electron is most likely to be found
The position of an electron determines what?
Their potential enegry

Electrons farther from the nucleus have what?

More energy
Isotopes in the environment can do what?
Radioactive dating
What is redox?

During some chemical reactions, electrons can be transferred from one atom to another while still retaining the energy of their position in the atom
What is oxidation?
Loss of an electron

What is reduction?

Gain of an electron
What are valence electrons?

Number of electrons in outermost energy level?

Inert (nonreactive) elements have how many electrons in their outermost shell?


8

What is the octet rule?

Atoms tend to establish completely full outer energy levels
What are the different types of bonds?


Chemical


Ionic


Covalent

What is a chemical bond?


Molecules are groups of atoms held together in a stable association


Compounds are molecules containing more than one type of element


Atoms are held together molecules or compounds by chemical bonds

What are ionic bonds?


Formed by the attraction of oppositely charged ions



What are the characteristics of ionic bonds?

Metal - non-metal


Generally weak


Gain or loss of electrons forms ions


Electrical attraction of water molecules can disrupt forces holding ions together

What is a covalent bond?

Forms when two atoms share 2 or more valence electrons
What are the characteristics of covalent bonds?


Two non-metals


Result in no net charge, satisfies octet rule, no unpaired electrons


Strength of covalent bond depends on the number of shared electrons but are generally strong


Many biological compounds are composed of more than 2 atoms - may share electrons with 2 or more atoms

What is electronegativity?

Atoms affinity for electrons (how strongly atoms will attract electrons)

Differences in electronegativity dictate what?


How electrons are distributed in covalent bonds

What are non-polar covalent bonds?

Equal sharing of electrons

What are polar covalent bonds?

Unequal sharing of electrons
What is the most electronegative element?


Fluorine - it only needs one electron to fill outer shell


Oxygen and Chlorine are two others

A chemical reaction involves what?

The formation or breaking of chemical bonds

How do chemical reactions work?

Atoms shift from one molecule to another without any change in number or identity of atoms

What are reactants in a chemical reaction?


Original molecules

What are products in a chemical reaction?

Molecules resulting from reaction
What are chemical reactions influenced by?


Temperature


Concentration of reactants & products


Catalysts

Are many chemical reactions reversible?


Yes :)
Life is inextricably tied to what?

Water

The single most outstanding chemical property of what is its ability to what?


Form hydrogen bonds


-Weak chemical associations that form between the partially negative O atoms and the partially positive H atoms of two water molecules

What bonds are highly polar within a water molecule?

Oxygen and hydrogen
Oxygen is more electronegative than what?

Hydrogen
What kind of charges develop in a water molecule?


Partial electrical charges develop


Oxygen is partially negative


Hydrogen is partially positive

What is a nonpolar covalent bond?


Bonding electrons shared equally between two atoms


No charges on atoms

What is a polar covalent bond?

Bonding electrons shared unequally between two atoms


Partial charges on atoms.

What is an ionic bond?


Complete transfer of one or more valence electrons


Full charges on resulting ions

What is cohesion?

Water molecules stick to other water molecules by hydrogen bonding

The attraction through cohesion produces what?

Hydrogen bonds
The individual hydrogen bonds are what?

Weak and transitory

Hydrogen bonds are responsible for what?


Many of waters important physical properties
What is adhesion?
Water molecules stick to other polar molecules by hydrogen bonding
A large amount of energy is required to change what about water?

The temperature because water has a high specific heat

The evaporation of water from a surface causes what?


Cooling of that surface
What is hydrophilic?

Water loving

What is hydrophobic?


Water fearing
What is the pH of pure water?

7


Considered neutral


Neither acidic nor basic

What is pH?


The negative logarithm of hydrogen ion concentration of solution
What is an acid?


Any substance that dissociates in water to increase the [H+] (and lower the pH)

What happens as an acid gets stronger?

More hydrogen ions get produced and the pH get lower

What is a base?
A substance that combines with H+ dissolved in water, & thus lowers the H+
What are buffers?

Substances that resists changes in pH

How to buffers act?


Releasing hydrogen ions when a base is added


Absorbing hydrogen ions when acid is added


Overall effect of keeping [H+] relatively consistent

Why are biological buffers important?

To stop things like respiratory acidosis, respiratory alkalosis, metabolic acidosis, & metabolic alkalosis from happening

What do most biological buffers consist of?

A pair of molecules, one acid and one base
Carbon is considered what kind of molecules

Carbon tha ho molecule
Organic chemistry is the study of what?

Carbon compounds
Why are C atoms versatile building blocks?

Because they have bonding properties and 4 stable covalent bonds

What is the simplest C molecule?


Hydrocarbon


-Combinations of C & H

What is the simplest HC molecule?

Methane

What are the characteristics of methane?


1 Carbon bound to 4 H atoms


Non polar


Not soluble in water


Hydrophobic


Stable


Very little attraction between molecules


A gas at room temp

How do hydrocarbons grow?

Adding C-C bonds


Straight line


Branching


Ring

What hydrocarbons grow in a straight line?

Ethane & Hexane

What hydrocarbons grow by branching?

Isohexane

What hydrocarbons grow in a ring?


Cyclohexane (Like a cyclone, is a ring)
What are isomers?


Molecules with same molecular formula but different structures & therefore functionally different with different chemical properties

What are the types of isomers?

Structural


Geometric


Stero

What are structural isomers?

Molecules differ in structural arrangement of atoms
What are geometric isomers?


Molecules differ in arrangement around C=C double bond


Same covalent partnership

What are stero isomers?

Molecules which are mirror images of each other


-C bonded to 4 different atoms or groups


---Asymmetric


-Left and right handed versions


--"L" versions are biologically active

Structural differences in stero isomers create important functional significance such as?

Amino acid alanine


-L alanine used in proteins but not D (R)-alanine


Medicine


-L version active but not D(R)- version


When the wrong version of the isomer is used it can result in tragedy

What caused "one of the biggest medical tragedies of modern times"?


Thalidomide


Prescribed to women in the 50's & 60's for morning sickness but stereoisomers caused severe birth defects

What are functional groups?


Components of organic molecules that are involved in chemical reactions


-Gives organic molecules distinctive properties

The basic structure of male & female hormones are identical but


Attachment of different functional groups


Interact with different targets in the body

What are the 6 functional groups most important to chemistry of life?


Hydroxyl


Carbonyl


Carboxyl


Amino


Sulfhydryl


Phosphate

What affects the reactivity of functional groups?


Hydrophilic


Increase solubility in water

What is hydroxyl?


-OH


Organic compounds with OH = alcohols, sugars


Names typically end in -ol


-ex. Ethanol & Glycerol


Polar


Forms H-bonds with water to help

What is carbonyl?


-C=O


-O double bonded to C


If C=O at end of molecule = aldelhyde


If C=O in the middle of molecule - ketone

What is carboxyl?


-COOH


C double bonded to O & single bonded to OH group


Compounds with COOH = acids


Loses H= easily - makes solutions acidic


--Fatty Acids


--Amino Acids

What is amino?

-NH2


N attached to 2 H


-Compounds with NH2 = amines


--Amino acids


NH2 acts as base


-Ammonia picks up H+ from solution

What is sulfhydryl?


-SH


S bonded to H


-Compounds with SH = thiols


-SH groups stabilize the structure of proteins


Smells like rotten eggs and sewage

What is phosphate?

-PO4


P bound to 4 O


-Connects to C through an O


-PO4 are anions with 2 negative charges


-Function of PO4 is to transfer energy between organic molecules (ATP)


Forms phospholipids and DNA

What is methyl?


Affects gene expressions


-Compounds become "methylated"


-This affects shape & function of the molecule


-Hydrophobic

What are macromolecules?

Smaller organic molecules join together to form larger molecules

What are the four major classes of macromolecules?


Carbohydrates


Lipids


Proteins


Nucleic Acids

What are monomers?


Building blocks


Repeated small units




What is dehydration synthesis?
The process of joining two molecules, or compounds, together following the removal of water
What is hydrolysis?

The chemical breakdown of a compound due to reaction with water

What are carbohydrates? (Besides my main food group)



Composed of C, H, & O
What are the functions of Carbohydrates?


Fast energy


Raw Materials


Energy Storage


Structural Materials


What is a monomer of carbohydrates?


Sugars


Ex. Sugars, starches, cellulose

How can you identify sugar molecules?

Most names for sugar end in -ose

How are sugars classified?


By the number of carbons


6C = Hexose (glucose)


5C = Pentose (ribose)


3C = Triose (glyceraldehyde)

Functional groups determine what?


Function


Example: If C=O is at the end of a chain of carbonyl its aldehyde but if its in the middle its a ketone

5C & 6C sugars form what?

Rings in solution
Three types of sugar saccharides?


Monosaccharaides


Disaccharides


Polysaccharides

What is a monosaccharide?


Simple 1 monomer sugars


Ex. Glucose


What is a disaccharide?


2 monomer sugar


Ex. Sucrose

What is a polysaccharide?


Large polymers


Ex. Starch

What are the functions of a polysaccharide?


Energy storage


-Starch (plants)


-Glycogen (animals)


--In liver & muscles


Structure


-Cellulose (plants)


-Chitin (arthropods & fungi)

Digesting starch vs. cellulose


Starch is easy to digest


Cellulose is hard to digest

Cellulose in the most what?

Abundant compound on Earth

What are lipids composed of?


C, H, O


Long hydrocarbon chain

What are the three types of lipids?


Fats


Phospholipids


Steroids


Do lipids form polymers?


No, big molecules made of subunit smaller molecules


NOT a continuing chain

What is the structure of lipids?


Glycerol (3C alcohol) + fatty acid


-Fatty acid = long HC "tail" with COOG group at "head"

Fat is also known as what?


Triacylglycerol


-3 fatty acids linked to glycerol


-Ester linkage between OH & COOH

Are fats polar or nonpolar?

Nonpolar

Are fats hydrophilic or hydrophobic?

Hydrophobic

What are the functions of fats?


Energy storage


-very rich


-2x carbs


Cushions organs


Insulates body



How are saturated fats bonded?


All C bonded to H


No C=C double bonds


-Long, straight chain


-Most animal fats


-Solid at room temp


-- Butter, coconut oil, etc.

How are unsaturated fats bonded?


C=C double bonds in the fatty acids


-Plant & fish fats


-Vegetable oils


-Liquid at room temp

What is the structure of phospholipids?


Glycerol + 2 fatty acids + PO4


-PO4 negatively charged


-Other small molecules may also be attached


--adenine (ATP)

Are phospholipids hydrophobic or philic?


Fatty acid tails = hydrophobic


PO4 = hydrophilic head


-dual "personality"

How do phospholipids react in water?


Hydrophilic heads attracted to H2O


Hydrophobic tails "hide" from H2O


-Self-assemble into aggregates


--micelle


--liposome


--early evolutionary stages of a cell

Where do we find phospholipids?

Inside cell membranes
How do phospholipids react in the cell membrane?

Form a bilayer


Hydrophilic heads on outside


Hydrophobic tails on inside form core


Forms barrier between cell & external environment

What are steroids?


Ex. Cholesterol, sex hormones


4 fused C rings


-different steroids created by attaching different functional groups to rings

What is the important cell component of cholesterol?

Found in animal cell membranes


Precursor of all other steroids


-Including vertebrate sex hormones


High levels in blood may contribute to cardiovascular disease

What are the functions of nucleic acids?

Store & transmit hereditary information

What are some examples of nucleic acids?


RNA (ribonucleic acids)


DNA (deoxyribonucleic acids)


What are the structures in nucleic acids?

monomers = nucleotides
What are the 3 parts of nucleotides?


Nitrogen base (C-N ring)


Pentose sugar (5C)


-Ribose in RNA


-Deoxyribose in DNA


PO4 group

What are the two types of nucleotides?


Purines & Pyrimidines


2 types of nucleotides

What is the make up of purines?


Double ring N base


Adenine (A)


Guanine (G)


What is the make up of pyrimidines?


Single ring N base


Cytosine (C)


Thymine (T)


Uracil (U)

What is the backbone of a nucleic polymer?


Sugar to PO4 bond


Phosphodiester bond


N bases hang off the sugar-phosphate backbone

How does a Phosphodiester bond work?


New base added to sugar of previous base


Polymer grows in one direction

RNA is what kind of nucleotide chain?

A single nucleotide chain

DNA is what kind of nucleotide chain?


Double nucleotide chain


-N bases bond in pairs across chains


-Spiraled into a double helix

Nucleotides bond between DNA strands to form what?


H bonds


Purine::Pyrimidine

What are the types of H bonds?


A::T


G::C



What is the function of an information polymer?


Series of bases encodes information


Stored information is passed from parent to offspring


Stored information is also known as genetics

What are proteins?
Most structurally & functionally diverse group of biomolecules

What are the functions of proteins?

Involved in almost everything:


Enzymes


Structure (keratin & collagen)


Carriers & transport (membrane channels)


Receptors & binding (defense)


Contraction (actin & myosin)


Signaling (hormones)


Storage (bean seed proteins)

What is the structure of proteins?


Monomer = amino acids


-20 different amino acids


Polymer = polypeptide


-Protein can be 1 or more polypeptide chains folded & bonded together


-Large & complex molecules


-Complex 3D shape

What is the structure of amino acids?


Central Carbon


Amino Group


Carboxyl Group (acid)


R Group (side chain)


-Variable group


-Confers unique chemical properties of the amino acid

What are the building proteins in a polypeptide chain?


N-terminal = NH2 end


C-terminal = COOH end


Repeated sequence (N-C-C) is the polypeptide backbone which grows in one direction