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60 Cards in this Set
- Front
- Back
Things necessary for normal cell function |
Oxygen and glucose |
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One fundamental purpose of emergency care |
Maintaining adequate delivery 9f oxygen and glucose |
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Cellular metabolism |
Body breaks down glucose to produce energy |
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By products of aerobic metabolism |
Heat carbon dioxide and water |
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Important cell function that requires atp |
Sodium potassium pump |
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Sodium |
Outside the cell (meaning they were inside before) |
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Potassium |
Inside the cell (meaning they were outside before) |
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Glucose broken down without the presence of oxygen produces |
Pyruvic acid-->lactic acid(harmful to cell/body funtion) and small amount of atp |
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1st stage and 2nd stage of cellular metabolism |
1. Anaerobic---> cytosal 2. Aerobic---> mitochondria |
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Perfusion |
Delivery of oxygen glucose and other nutrients to cells as well as elimination of waste from cells |
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Ambient air percentages |
79% nitrogen 21% oxygen 1% trace amounts of carbon dioxide |
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FiO2 is the fraction of |
Inspired oxygen |
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Carbon monoxide and cyanide disrupts the ability of |
Blood to carry oxygen to the cells |
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Hypoxia |
Lack of oxygen |
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Boyles law |
Volume of a gas is inversely proportional to the pressure |
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Pressure of atmospheric air |
760 mmHg at sea level |
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Prior to inhalation, pressure in chest is |
758 mmHg |
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During exhalation pressure of air is |
761 mmHg in chest |
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Air flows from |
Higher pressure to lower pressure |
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Minute volume |
Tidal volume × frequency of ventilation |
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Average minute volume |
500 ml × 12/ minute= 6000 ml |
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Increase in ventilatory rate can |
Compensate for reduced tidal volume ...to a point |
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Low tidal volume may lead to |
Insufficient volume of air reaching alveoli for gas exchange |
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Dead air space |
Air that doesn't reach alveoli |
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Amount of actually air out of 500 ml that reaches alveoli |
350 ml |
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Chemo receptors both central and peripheral... |
Monitor the pH co2 and o2 levels in arterial blood |
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Central receptors are located |
Near the respiratory center in the medulla |
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Peripheral chemorecpetors are located |
In the aortic arch and the carotid bodies |
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COPD patients have a tendency to retain |
CO2 |
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COPD (chronic obstructive pulmonary disease) patients respiration are controlled by decreased oxygen levels |
Hypoxic drive |
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3 types of receptors in lungs that regulate respiration |
1. Irritant 2.stretch 3. J receptors |
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Irritant receptors |
Found in airways, sensitive to gases and stimulate coughing and bronchoconstriction |
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Stretch receptors |
Found in smooth muscle of airways, protect in inflammation of lungs |
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J receptors |
Found in capillaries surrounding alveoli, they stimulate rapid and shallow ventilation |
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Respiratory control centers in the brain |
Dorsal group--medulla oblongata further input to Ventral on rate and depth Ventral group--medulla oblongata, controls basic pattern of breathing, sends sensory input to spinal chord to stimulate diaphragm and intercontinental muscles Pontine group--sends signals to Ventral to turn off inhalation |
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V/Q rate |
Ventilation and perfusion rate in alveolar capillaries |
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1000 ml of oxygen are delivered to the cells every |
Minute |
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Hemoglobin have ___ iron molecules |
4 and each one can bind to a molecule of oxygen |
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Oxygen bound hemoglobin |
Oxyhemoglobin |
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Non oxygen bound hemoglobin are called |
Deoxyhemoglobin |
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Oxygen is carried through the blood |
98 % Ish bound to hemoglobin 2% Ish in plasma |
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Carbon dioxide is transported in the blood as |
7% In plasma 23 % attached to hemoglobin 70% as bicarbonate |
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Hydrostatic pressure |
Generated by the contraction of the heart and the blood pressure. Exerts a push inside the vessel or capillary |
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Plasma oncotic pressure |
Keeps fluid in the blood vessels |
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CO (cardiac output) |
Heart rate × stroke volume |
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Frank starling law of the heart |
(Rubber band theory) as blood fills the left ventricle, it stretches the muscle fibers, that stretch determines the force available to eject the blood from the ventricle |
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SVR |
SYSTEMIC VASCULAR RESISTANCE |
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Pulse pressure |
Difference between the systolic and diastolic BP |
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Narrow pulse pressure |
(Systolic- diastolic) × 25% |
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3 regulatory influences that control blood flow through capillaries |
Local (temp, hypoxia, acidosis, histamine), neural( sympathetic and parasympathetic NV) and hormonal factors (EPINEPHRINE) |
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Blood pressure = |
CO × SVR |
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Shock |
The insufficient delivery of oxygen and other nutrients to some of the body's cells and inadequate elimination of waste that results from inadequate circulation of blood |
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Preload |
The pressure generated in the left ventricle at the end of diastole |
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Stroke volume |
The volume of blood ejected by the left ventricle with each contraction |
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Blood composition |
🔹45 % formed elements -42to48 percent red blood cells -white blood cells -platelets 🔹55% plasma -91 percent water - plasma proteins...albumin, clotting factor and antibodies |
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Adults have ____ml of blood per kg of body weight |
70 ml |
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Minute volume |
Respiratory rate × tidal volume |
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