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60 Cards in this Set

  • Front
  • Back

Things necessary for normal cell function

Oxygen and glucose

One fundamental purpose of emergency care

Maintaining adequate delivery 9f oxygen and glucose

Cellular metabolism

Body breaks down glucose to produce energy

By products of aerobic metabolism

Heat carbon dioxide and water

Important cell function that requires atp

Sodium potassium pump

Sodium

Outside the cell (meaning they were inside before)

Potassium

Inside the cell (meaning they were outside before)

Glucose broken down without the presence of oxygen produces

Pyruvic acid-->lactic acid(harmful to cell/body funtion) and small amount of atp

1st stage and 2nd stage of cellular metabolism

1. Anaerobic---> cytosal


2. Aerobic---> mitochondria

Perfusion

Delivery of oxygen glucose and other nutrients to cells as well as elimination of waste from cells

Ambient air percentages

79% nitrogen


21% oxygen


1% trace amounts of carbon dioxide

FiO2 is the fraction of

Inspired oxygen

Carbon monoxide and cyanide disrupts the ability of

Blood to carry oxygen to the cells

Hypoxia

Lack of oxygen

Boyles law

Volume of a gas is inversely proportional to the pressure

Pressure of atmospheric air

760 mmHg at sea level

Prior to inhalation, pressure in chest is

758 mmHg

During exhalation pressure of air is

761 mmHg in chest

Air flows from

Higher pressure to lower pressure

Minute volume

Tidal volume × frequency of ventilation

Average minute volume

500 ml × 12/ minute= 6000 ml

Increase in ventilatory rate can

Compensate for reduced tidal volume ...to a point

Low tidal volume may lead to

Insufficient volume of air reaching alveoli for gas exchange

Dead air space

Air that doesn't reach alveoli

Amount of actually air out of 500 ml that reaches alveoli

350 ml

Chemo receptors both central and peripheral...

Monitor the pH co2 and o2 levels in arterial blood

Central receptors are located

Near the respiratory center in the medulla

Peripheral chemorecpetors are located

In the aortic arch and the carotid bodies

COPD patients have a tendency to retain

CO2

COPD (chronic obstructive pulmonary disease) patients respiration are controlled by decreased oxygen levels

Hypoxic drive

3 types of receptors in lungs that regulate respiration

1. Irritant


2.stretch


3. J receptors

Irritant receptors

Found in airways, sensitive to gases and stimulate coughing and bronchoconstriction

Stretch receptors

Found in smooth muscle of airways, protect in inflammation of lungs

J receptors

Found in capillaries surrounding alveoli, they stimulate rapid and shallow ventilation

Respiratory control centers in the brain

Dorsal group--medulla oblongata further input to Ventral on rate and depth


Ventral group--medulla oblongata, controls basic pattern of breathing, sends sensory input to spinal chord to stimulate diaphragm and intercontinental muscles


Pontine group--sends signals to Ventral to turn off inhalation

V/Q rate

Ventilation and perfusion rate in alveolar capillaries

1000 ml of oxygen are delivered to the cells every

Minute

Hemoglobin have ___ iron molecules

4 and each one can bind to a molecule of oxygen

Oxygen bound hemoglobin

Oxyhemoglobin

Non oxygen bound hemoglobin are called

Deoxyhemoglobin

Oxygen is carried through the blood

98 % Ish bound to hemoglobin


2% Ish in plasma

Carbon dioxide is transported in the blood as

7% In plasma


23 % attached to hemoglobin


70% as bicarbonate

Hydrostatic pressure

Generated by the contraction of the heart and the blood pressure. Exerts a push inside the vessel or capillary

Plasma oncotic pressure

Keeps fluid in the blood vessels

CO (cardiac output)

Heart rate × stroke volume

Frank starling law of the heart

(Rubber band theory) as blood fills the left ventricle, it stretches the muscle fibers, that stretch determines the force available to eject the blood from the ventricle

SVR

SYSTEMIC VASCULAR RESISTANCE

Pulse pressure

Difference between the systolic and diastolic BP

Narrow pulse pressure

(Systolic- diastolic) × 25%

3 regulatory influences that control blood flow through capillaries

Local (temp, hypoxia, acidosis, histamine), neural( sympathetic and parasympathetic NV) and hormonal factors (EPINEPHRINE)

Blood pressure =

CO × SVR

Shock

The insufficient delivery of oxygen and other nutrients to some of the body's cells and inadequate elimination of waste that results from inadequate circulation of blood

Preload

The pressure generated in the left ventricle at the end of diastole

Stroke volume

The volume of blood ejected by the left ventricle with each contraction

Blood composition

🔹45 % formed elements


-42to48 percent red blood cells


-white blood cells


-platelets


🔹55% plasma


-91 percent water


- plasma proteins...albumin, clotting factor and antibodies

Adults have ____ml of blood per kg of body weight

70 ml

Minute volume

Respiratory rate × tidal volume

...