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86 Cards in this Set

  • Front
  • Back
  • 3rd side (hint)

What is your diagnosis? Give the different types

Photodermatitis


1.primary (preformed or metabolically derived photodynamic agent)


2.hepatogenous (phyloerythrin)


3.aberrant pigment synthesis (porphyria)


4.idiopathic

Source of photodynamic agent :Give an exemple of one plant and one chemical

Back (Definition)

Give your diagnosis and a predisposed breed

Alopecia areata


Eringer cow

DD of alopecia areata

Follicular dysplasia

What is your diag. Give the histo

Chorioptic mange


Chorioptes bovis 0,3-0,5mm


Histo : hypereosino perivascular to interstitial dermatitis with eosino epidermal microabcess and paraK hyperK

What are the possible agent for bovine dermatophytosis ?

T. Verrucosum


(T. Mentagrophytes, T equinum, M gypseum, M canis, M nanum)

Diagnosis and ethiology

Dermatophytosis


M. Nanum


(M canis, M gypseum, M persicolor, T mentagrophytes, T verrucosum, T tonsurans)

About treatment for dermatophytosis in cow with topical enilconazole: what can you say about the following concentration: 4 & 5%, 3%, 1-2%

4-5%: success but ADR in 40 and 55%


3% : success rate 95% and no ADR


1-2% : success rate 25 and 50%


—> 3% once a day 3 days

Enilconazole = imidazole that inhibits biosynthesis of ergosterol and disruptif permeability of cell wall

In cow T verrucosum immunity is only cell mediated: R or W

Wrong : cell mediated and humoral

Causative agent in impetigo on cow

Staphylococcus aureus

Diagnosis - agent - What is it on the right photo

Actinomycosis


Actinomyces bovis (oral cavity commensal); occasionally A. Israelii


Sulfur granules

DD of actinomycosis in cow (ethiologic agent)

Actinobacillus lignieresii


Trueperella pyogenes


Corynebacterium pseudoT

Cytologic exam of actinomycosis: What do you see

Supputative to pyogranulomatous


Gram + filament long or V,Y,T form

Histo of actinomycosis in cow and pigs

Nodular to diffuse suppurative to pyogranulomatous dermatitis and panniculitis. Tissus granules are coated with splendore hoeppli material and contain gram + filament

Diag

Aspergillosis

Give the 4 main lices of bovine

Sucking lice


-Linognathus vituli


-Solenopotes capillatus


-Haematopinus eurysternus


Biting lice


-Damalinia bovis

Common lice of ovine

Linognathus ovillus, stenopsis, pedalis


Damalinia ovis, caprae

Common porcine lice

Haematopinus suis

Caprine lice

Linognathus stenopsis and africanus


Damalinia limbartus, crassipes and caprae

What parasitic disease is reportable ?

Mange in cattle (sarcoptes, psoroptes, chorioptes)


In sheep (psoroptes ovis)

Give the 4 main flies problem and associated species in cow

Back (Definition)

Diagnosis and 2 ethiologic agents

Staphylococcus aureus


Staphylococcus hyicus (less commonly)

Histological exam

Nodular to diffuse suppurative or pyogranulomatous dermatitis and panniculitis with intracellular bacteria. Lymphangitis often not seen

What is your diagnosis

Dermatophilosis


Dermatophilus congolensis


Zoonotic

Diagnosis

Actinobacillosis


Same histo than actinomycosis but with gram - coccobacilli

What parasitic disease ?

Psoroptic mange


Psoroptes ovis (bovis)

Name the demodex species of cattle

Demodex bovis


(D ghanensis, D tauri but no disease associated)

What is the intermediate hosts of stephanofilariasis ?

Fly are intermediate hosts for the nematode


- hematobia


-musca

About foot and mouth disease: name the ethiologic agent and the species that can be infected

Aphtovirus (A, O, C, SAT1, SAT2, SAT3 & Asia 1)


Sheep, goat, swine, cattle

Morbidity and mortality are very high in foot and mouth disease: T or F?

F : morbidity 50-100 %


Mortality < 5%

Lumpy skin disease : agent and vector

Capripoxvirus


Insects especiallu stomoxys calcitrans

Most common form of epidermolysis bullosa in cattle

Junctional (autoso R)


In Simmental it is simplex and auto D

Give 2 common bacteria in intertrigo in cattle

Staphylococcus and fusobacterium necrophorum

What are the characterisitic of moist and dry gangrene ?

Moist = impaired venous and lymphatic drainage + infection



Dry= impaired arterial supply

Give the 4 subgroups of Bovine Papillomavirus and the BPV présent in each group

Papillomavirus


Xi: BPV 3, 4, 6, 9, 10, 11, 12


Delta : BPV 1, 2, 13, 14


Epsilon : BPV 5, 8


Dioxy : BPV 7

How many oncogenes are known in Bovine Papillomavirus and briefly describe their role

E1 to E8 : early genes; replication and transformation/interaction with genome


L1 & L2 : late genes; capsid protein

How many oncogenes are known in Bovine Papillomavirus and briefly describe their role

E1 to E8 : early genes; replication and transformation/interaction with genome


L1 & L2 : late genes; capsid protein

What are the most important oncongene in equine sarcoids?

E2, E5, E6, E7

Dermatophilus congolensis can cause strawbery foot rote in sheep: T or F

True

Give the result (positive or negative) of the nitrate réduction test for the caseous lymphadenitis in small ruminants, cattle and horses

Small rt : nitrate neg


Cattle : nitrate + and -


Horse : nitrate +

Pathogenesis of photosensitization

1.UV (320-400) absorbed by photodynamic agents in the skin


2.release of energy


3.production of reactive oxygen molecules (free radicals)


4.mast cell degranulation + proinfla mediators (IL1, TNFa...)


5.damage cell membrane, nucleic acid and prot

Give the susceptible parasites for ivermectin, doramectin, moxidectin, eprinomectin (sarcoptes, chorioptes, psoroptes)

Ivermectin (sc) and doramectin (sc or im) (0.2mg/kg sc every 2-3w): all


Moxidectine 0.2mg/kg pour on: psoroptes, chorioptes


Eprinomectin 0.5mg/kg pour on: chorioptes, sarcoptes

Name 2 psoroptic mange in goat

Psoroptes bovis


Psoroptes cuniculi

What demodex can be found in caprine

Demodex caprae

What is this parasite on a goat

Parelaphostrongylus tenuis

Most probable viral dermatitis

Orf = contagions viral postulat dermatitis = contagions echtyma


Parapoxvirus

Morbidity and mortality of contagious viral pustular dermatitis (orf) in goat

100%


1%

Goat


1.Diagnosis


2.Histo

Orf


Eosinophilic intracytoplasmic inclusion body

No pruritus and no pain


What is your diagnosis

Psoriasiform dermatitis

This is a papilloma on a goat


Does it usually regress spontaneously?

No and in some case can transform into SCC

Diagnosis

Orf

What is the major vector for bleu tongue orbivirus?

Culicoides spp

What is it? What si the infectious agent ?

Dermatophilosis


Dermatophilus congolensis

Highly pruritic


What is your main differential ?

Psoroptic mange


Psoroptes ovis


Occasionally psoroptes cuniculi

Give the Different forms of foot/interdigital infections in cattle and sheep

1. Digital dermatitis (mortellaro disease, foot warts...) - treponema


2. Interdigital dermatitis - dichelobacter nodosus


3. Interdigital necrobacillosis (foot rot) - fusobacterium & Prevotella


4. Strawberry foot (sheep) - dermatophilus & fusobacterium / orf

Your diagnosis

Orf

Name the disease and the cause

Orf


Parapoxvirus ovis

First area affected in the orf

Non wooled areas

Pathognomonic sign of the blue tongue disease (ovine catarrhal fever)

Dark red to purple band in the skin just above the coronet

Your most probable diag


It is pruritic

Atopic dermatitis

Disease and pathogen

Fleece rot


Pseudomonas spp

Name the two types of porphyria in cattle

Congénital eryhtropoietic porphyria


Bovine protoporphyria

In ovine, what papilloma can become a SCC ?

Facial fibropapillomas

Give the name of this syndrome and the mutation

Tricho-dento-osseus-like syndrome in a Brown Swiss calf


DLX3 mutation

Disease and breed associated

Alopecia areata


Eringer cow

On alopecia areata of Eringer cow there are only T lymphocyte in the lesion : T or F

F


also CD20 + lymphocyte (B lymphocyte)

What causes bovine besnoitiosis ?

Besnoitia besnoiti : obligate intracellular apicomplexan protozoan parasite

Morbidity and mortality of Besnoitiosis

Morbidity 80%


Mortality 10%

How many layers does a cyst of besnoitiosis has ?

3

Adult onset of diffuse alopecia in two cows has been described. Histo showing follicular distortion and atrophy, melanin clumping. Give two breeds of the cows

Black angus


Black brangus cross

Risks factors for hock lesions in cow include : Time of the year, type of stalls, nature of bedding and stage of lactation.


T or F : in addition cattle with dirtier hocks are less affected.

True

Give the three treponema phylogroups identified in lesions from cattle, sheep, goat and elk digital dermatitis, pig skin affection and hock open wound in cattle

T medium phylogroup


T phagedenis phylogroup


T pedis phylogroup

This is a case of alopecia with hypo para thyroidism


What parameters are characteristic of this disease when you take a blood sample ?(3 parameters)


What do you see at the histo? (3 éléments)

Hypocalcemia, low parathyroid hormon (PTH), normal magnesium concentration


Histo= severe epidermal hyperplasia, orthoK hyperK, diffuse follicular atrophy

Name the endocrinopathy associated with this

Progressive alopecia associated with hypoparathyroidism

What is the infections agent of the lumpy skin disease in cattle ?


Give 2 diagnostic methods

Lumpy virus (capripox virus)


PCR and LAMP (loop mediated isothermal amplification) - Se and Sp are good according to recent study and can identify population at risk because détection in apparently healthy individual

What is your diagnosis

Haematobia irritans

Give a mutation identified in a sheep with dermatosparaxis

ADAMTS2


Normally this enzyme process procollagen I

What is the main pathogen responsible for Contagious ovine digital dermatitis ?

Treponema

Most probable Diagnosis

Ichthyosis fetalis

Give the two types of congenital forms of ichthyosis in cattle

1)Ichthyosis fetalis = harlequin fetus : non viable - chianina, holstein friesian, brown swiss...


2)ichthyosis congenita : milder form - chianina, holstein friesian, jersey...

Mutation of ichthyosis fetalis in chianina cattle

ABCA12

What form of EB was described in churra lamb in 2015 ?

Generalized severe junctional EB


Auto recessive

Irritant contact dermatitis : macerated tissues are more susceptible to irritant


T or F ?

T : be careful when using shampoo or water : must dry properly after

Irritant contact dermatitis : macerated tissues are more susceptible to irritant


T or F ?

T : be careful when using shampoo or water : must dry properly after

What oral therapy can you give for irritant contact dermatitis ?

Prednisolone and pentoxifylline (25mg/kg/12h)

During irritant contact dermatitis langerhans cells can go into the dermis and switch into macrophages : what elements are needed for this switch ?

- fibroblast


- E-cadherin


- IL 10