• Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

Card Range To Study

through

image

Play button

image

Play button

image

Progress

1/81

Click to flip

Use LEFT and RIGHT arrow keys to navigate between flashcards;

Use UP and DOWN arrow keys to flip the card;

H to show hint;

A reads text to speech;

81 Cards in this Set

  • Front
  • Back

Neurotransmitter Lifecycle

1. Synthesis 2. Vesicle Packaging 3. Vesicle Fusion/Relase 4. Activation 5. Remove from Synaptic Cell

Cocaine Half Life

45-75 minutes

Alcohol Synapse

GABA Glutamine DA

Stimulants

Excite CNS - blocking reuptake of dopamine, norepinephrine, serotonin

Cocaine Cultivated

Coca leaf, peru, amazon, 2-8,000 ft elevation

Cocaine - Forms

Paste / Hydrochloride / Freebase / Crack

Caffeine - CNS

Antagonist - adenosine block

Most traded after petroleum

Coffee

Supplements

Unregulated, cannot be sold for specific illness

Alcohol metabolize

Ethanol breakdown

Korsakoff Syndrome

Severe Anterograde Amnesia

Major Brain Structures

Cortex / Basal Ganglia / Hypothalamus / Limbic / Midbrain, pons, medulla

Basal Ganglia

Muscle Tone

Midbrain

Emotion, location memory, physical activity

MAOI

Antidepressant

1970 Comprehensive Drug Abuse Prevention

DHS - more funding DEA - control

Laissez- Faire

Toxicity, Dependence, Crime

Dopamine

Neurotransmitter found in Basal Ganglia. Feel good

Neuron

Cell body - Nucleus Dendrites - Receptors Axon - Conduct Activation Presynap Terminal - End of axon

Glia cells

Firmness and structure

Sympathetic

Fight or Flight

Parasympathetic

Recover

Somatic Nervous System

External, Sensory, Cranial, Vision, Hearing, Taste

Psychoactive Principle

Not good or bad / multiple effects / size quality / history expectations

Replaced barbiturates

Benzodiazepine

Non-benzodiazepines

Sleep

Benzodiazepine trade names

Rohypnol, xanax, ativan

Designer Drug Meth

Ecstasy

Highly Dependent Illicit Drugs

Heroin (IV) Crack

Drugs/Crime

Changes personality, under the influence, obymtain money, illicit drug use is a crime

4 drugs that triggered federal law

Marijuana, Amphetamine, Barbiturates, Hallucinogens

1970 Controlled Abuse Substance Act

Direct Federal regulations DHS increased funding, DEA created to oversee

1988 Amendments

Target Users and Organized Crime

1906

FDA Pure Act - Labeling

Harry Anslinger

1937 Marijuana Tax Act

Schedule 1 vs Schedule 2

Medical acceptance

Homeostasis

Staying the same - body temp, blood pressure

Glia vs Neuron

Neurons - nerve cells that analyze and transmit to Glia cells within brain

Sympathetic Neurotransmitter

Norepinephrine

Parasympathetic Neurotransmitter

Acetylcholine

Basal Ganglia

Dopamine - Muscle Tone

Mesolimbic Pathway

Assist with dependence, electrical stimulation, postive reinforcement

Alzheimes

Acetylcholine - nucleus baslia

Inhibitory Neurotransmitter

GABA

Excitory Neurotransmitter

Glutamine

Drugs interact with neurotransmittera

At Synapse or directly with Receptors

Herion

Opioid

Cocaine

Stimulant

Alcohol

Depressant

LSD

Hallucinogen

Prozac

Psychotherapeutic

LD50 > ED50

Lethal > Effective

Deactivation

Excreted / unchanged / no longer same effect

Monoamine theory of mood

Too little MA neurotransmitter such as serotonin and dopamine cause depression

Dosage questions

Effective dose? Toxic? Safety Margin? Adverse Reaction?

Metabolite

Product of enzyme action

Presence at certain concentration

Specific drug effects

Multiple Sclerosis

Loss of Glia

Time Course

Admin of drug and effect over time

Ataxia

Uncoordinated Walking

Small intestine

Organ absorption blood stream

Nalaxone

Opioid antagonist herion addiction - generic name

Deltoid Muscle

Rapid absorption

Safety Margin

Difference between effective and toxic

Invented Opioids

China

Low dose - sedative High dose Sleep

Depressant

Upper

Stimulant

Downers

Depressant

Monoamine neurotransmitter

Dopamine, norepinephrine, serotonin

Cocaine / amphetamines

Monoamines - high dependence

Synthetic sympathomimetic

Amphetamine

Mariana

Coca wine

Freud

Depression

Halsted

Anethshia

Increased inhibitory GABA

Barbiturates Benzodiazepine

Mental hospital odor

Paraldehyde

Barbiturates

GABA receptor

Sedative hypnotic withdrawal

Anxiety, irritability, insomnia

Fluid balance

AntiDiuretic hormone decrease

Rapid onset

Psychological dependence

Short duration

Withdrawl symptoms