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7 Cards in this Set
- Front
- Back
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Cholestyramine
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MOA: bile-acid binding resin
IND: Adj therapy for pts with familial Hypercholesterolemia TOX: Constipation, GI discomfort, may interfere w/ int abs of other drugs |
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Statins
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MOA: HMGCoA reductase inhibitor
IND: Hypercholesterolemia TOX: Hepatotoxicity, rhabdomyolysis |
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Niacin
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MOA: Reduces release of VLDL from liver into circulation
IND: Hypercholesterolemia: to increase HDL and decrease LDL TOX: flushing, pruritus (both reversibe w/ aspirin), and hepatoxicity |
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Gemfibrozil, clofibrate
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MOA: stimulates lipoprotein lipase
IND: Hypercholesterolemia; to decrease decrease TGs TOX: Myositis, hepatotoxicity |
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Describe how each of the following drugs reduces angina:
B-blockers |
Decrease myocardial O2 use and decrease afterload, increase coronary filling during diastole
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Describe how each of the following drugs reduces angina:
Nifedipine |
Coronary arteriolar vasodilation
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Describe how each of the following drugs reduces angina:
Verapamil |
Slows cardiac conduction
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