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7 Cards in this Set

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Cholestyramine
MOA: bile-acid binding resin
IND: Adj therapy for pts with familial Hypercholesterolemia
TOX: Constipation, GI discomfort, may interfere w/ int abs of other drugs
Statins
MOA: HMGCoA reductase inhibitor
IND: Hypercholesterolemia
TOX: Hepatotoxicity, rhabdomyolysis
Niacin
MOA: Reduces release of VLDL from liver into circulation
IND: Hypercholesterolemia: to increase HDL and decrease LDL
TOX: flushing, pruritus (both reversibe w/ aspirin), and hepatoxicity
Gemfibrozil, clofibrate
MOA: stimulates lipoprotein lipase
IND: Hypercholesterolemia; to decrease decrease TGs
TOX: Myositis, hepatotoxicity
Describe how each of the following drugs reduces angina:

B-blockers
Decrease myocardial O2 use and decrease afterload, increase coronary filling during diastole
Describe how each of the following drugs reduces angina:

Nifedipine
Coronary arteriolar vasodilation
Describe how each of the following drugs reduces angina:

Verapamil
Slows cardiac conduction