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6 Cards in this Set
- Front
- Back
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Trifluridine |
Inhibits thymidine synthetase
Inhibits DNA synthesis in both virus-infected and normal host cells |
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Ganciclovir Ophthalmic |
Inhibits DNA polymerase
Incorporates into viral DNA |
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Acyclovir |
Inhibits viral DNA polymerase
Causes termination of the DNA chain and leads to irreversible inactivation of viral DNA polymerase |
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Valacyclovir |
Prodrug of acyclovir
Hydrolyzed by esterase's in the GI tract and liver converting more than 95% to acyclovir; bioavailibility significant better than acyclovir |
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Famciclovir |
Selectively affects viral DNA synthesis and inhibits replication similar to acyclovir |
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Ganciclovir - Vitrasert |
Inhibits DNA polymerase
Incorporates into viral DNA |
