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67 Cards in this Set
- Front
- Back
What are nucleic acids? |
They have the capacity to store the information that controls cellular activity |
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What do nucleic acids do? |
They control: - the specialization of celle to form tissues - arrangement of tissues into organs |
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What are the basic processes of life |
-movement - nutrition - respiration - excretion - growth - reproduction - responding to stimuli |
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What do nucleic acids do to enable organisms to carry out the basic processes of life ? |
They control the synthesis of proteins |
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What also act like proteins |
Enzymes |
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What do enzymes do? |
They control the chemical processes |
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What are the 2 nucleic acids found in cells |
- Deoxyribonucleic acid ( DNA ) - Ribonucleic acid ( RNA ) |
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Where is DNA found |
Mainly found in the nucleus of a cell where it forms an important part of the chromosomes that make up the chromatin network |
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What is chromatin? |
Chromosomal material made up of DNA, RNA and histone proteins as found in a non - dividing cell |
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What is extracellular DNA? |
Small amounts of DNA found outside the nucleus in mitochondria in plants and animals and in chloroplasts in plants |
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Why were they called chromosomes and what does that mean |
They absorb dye very easily which is why they were called chromosomes as this makes them visible under a microscope but they can only be seen as individual threads when a cell is dividing |
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Chromosomes ? |
Are long, thin, intertwined thread like structures made up of a strand of DNA wound around proteins |
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What is the wound around proteins called |
Histones |
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If histones are attached to DNA what does it do |
It helps it to coul up during cell division |
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In a body ( somatic ) cells chromosomes occur like what? |
Homologous pairs |
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What are genes |
Sections of DNA molecules that control hereditary characteristics |
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Who discovered the structure of DNA |
Maurice wilkins and rosalind Franklin |
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Who also became interested in DNA |
- Francis Crick - James Watson |
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What did James Watson discover ? |
Discovered spiral helical |
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Who won the Nobel prize for DNA |
Watson, crick and wilkins |
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What is the shape of DNA |
Is a long, twisted ladder, forming a stable, 3 dimensional double helix |
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What are nucleotides |
The double stranded DNA molecules Is made up of releating units, building blocks linked to form long nucleic acids chains |
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Each nucleotide is made up of |
- sugar molecules ( deoxyribose ) - phosphate molecule - nitrogenous base |
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What is the nitrogenous base made up of |
- adenine - thymine - guanine - cytosine |
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The four bases are what |
The foundation of the genetic code, instructing cells on how to synthesize enzymes and other proteins |
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How is the double helix made up |
- the outer 2 strands of the ladder are formed by a chain of alternating sugar/ phosphate links. - the rungs of the ladder are formed from pairs of bases linked by weak hydrogen bonds - the nitrogenous base pairs are attached to the sugar molecules |
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What does adenine bond with? |
Only bonds with thymine or uracil A = T A = U |
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What does Cytosine bond with |
Bonds with guanine C = G |
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There are 2 groups of nitrogenous bases |
- purines - pyrimidines |
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What are purines |
They are made up of 2 rings of nitrogen, oxygen and hydrogen atoms. Examples are guanine and adenine |
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Pyridmidines are what |
Made up I'd one rings of similar atoms and are therefore much smaller that purines Examples are thymine and cytosine and uracil |
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What is it known as when determining the order of the bases in a DNA chain |
DNA sequencing |
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What determines the genetic code |
The sequence of the four bases |
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How do organisms differ |
The sequences in which the base pairs are strung together |
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What is the role of DNA molecules |
- carry coded genetic information in each cell in the form of Gene's which provide a blueprint for an organisms growth and development by coding for a specific protein - can replicate |
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What are exons |
Protein coding regions of a DNA molecule |
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What are they interrupted by |
Non coding regions called introns |
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Non coding regions are known to form |
Functional RNA molecules |
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Replication |
Is the process of making a new DNA molecule from an existing DNA molecule which is identical to the original molecule |
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What phase does replication take place |
Interphase |
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Why is replication necessary |
The dna needs to produce another molecule exactly the same as itself to ensure that the genetic code is passed on to each daughter cell formed during cell division. |
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How does replication take place ? |
- the hydrogen bonds between the 2 strands break, allowing the strands to part - free nucleotides in the cytoplasm bond to their matching , exposed base partners - the 2 daughter DNA molecules each twist to form a double helix which then winds itself around the histones (proteins) forming a chromosome |
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What is the structure or RNA |
- consists of a single strand - the strand is much shorter - the sugar is ribose - it has 3 bases in common with DNA: adenine, cytosine, guanins but a base uracil replaces thymine |
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What is the function of RNA |
RNA carries instructions from DNA in the nucleus to the ribosomes in the cytoplasm of a cell where it controls the synthesis of proteins from amino acids |
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What are cell chemical processes controlled by |
Enzymes |
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What are the different types of rna |
- messenger rna ( mRNA ) - transfer rna ( tRNA ) - ribosomal rna ( rRNA) |
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What is transcription |
When mRNA is formed in the nucleus in the same way as DNAS replication takes places. |
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Transcription is the process whereby |
DNA makes and codes mRNA |
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How does transcription take place |
- the process starts when a small piece of DNA, a gene, unwinds and the two strands separate - new nucleotides pair up with their complementary bases on one of the dna strands. This strand is called the template as it Carrie's the code - the nucleotides join up to form a strand of mRNA. Therefore the dna transcribes its genetic code to the mRna - note that a uracil base will pair with an adenine base - a coveted strand of mrna breaks away from the dna. The dna then re-zips - the relatively small mrna moves through the pores of the nuclear membrane and Carrie's the genetic code to the ribosomes which are the sites of protein synthesis |
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What is an amino acids |
It is a long chain ( polymer) of small units |
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How many different amino acids are involved in protein synthesis |
20 |
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What determines what type of protein is made |
The order in which amino acids are linked |
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The sequence of amino acids is determined by |
Instructions from the genetic code |
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How is the genetic code carried |
Carried as a sequence of code words which are transcribed to the mRna |
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What is a codon |
When a codeword is made up of any three bases |
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How many codons are there |
64 |
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The three codons that did not code for an amino acid are called what |
Stop codons |
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What does the order of codons determine |
The sequence of amino acids which will determine which protein is made |
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What happens at the ribosome |
The mrna Hinds to the ribosome at the start codon. The codons of the mrna act as a template that determines the order in which the amino acids are linked |
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Each trna has 3 bases at one end called |
An anti codon |
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What do anti codons do |
Pick up specific amino acids found in the cytoplasm and transfers it to a ribosome |
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Translation of rna into proteins process |
- the ani codon bases link up to their complementary bases of the codon. As the code on the mrna is translated into a sequence of amino acids - the trna molecule is released to carry more of its specific amino acid to the ribosome - catalyzed by enzymes, the amino acids link together with peptide bonds to form polypeptide chain - the polypeptide chains link together to form the final functional protein |
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What is translation |
The process by which a specific protein is formed from a chain of amino acids due to the sequence of codons in the mrna which in turn was coded by the DNA |
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What is the role of rRNA |
The rrna moves from the codon to codon along the mrna reading the code. Therefore plays an important role in the controlling the process of protein synthesis |
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Where is the genetic code stored |
It is stored along the length of a dna strand as a sequence of the 4 bases |
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The nucleotides are arranged into how many groups |
3 |
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What does each codon do |
It codes for a particular amino acid |