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67 Cards in this Set

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  • Back

What are nucleic acids?

They have the capacity to store the information that controls cellular activity

What do nucleic acids do?

They control:



- the specialization of celle to form tissues


- arrangement of tissues into organs

What are the basic processes of life

-movement


- nutrition


- respiration


- excretion


- growth


- reproduction


- responding to stimuli

What do nucleic acids do to enable organisms to carry out the basic processes of life ?

They control the synthesis of proteins

What also act like proteins

Enzymes

What do enzymes do?

They control the chemical processes

What are the 2 nucleic acids found in cells

- Deoxyribonucleic acid ( DNA )


- Ribonucleic acid ( RNA )

Where is DNA found

Mainly found in the nucleus of a cell where it forms an important part of the chromosomes that make up the chromatin network

What is chromatin?

Chromosomal material made up of DNA, RNA and histone proteins as found in a non - dividing cell

What is extracellular DNA?

Small amounts of DNA found outside the nucleus in mitochondria in plants and animals and in chloroplasts in plants

Why were they called chromosomes and what does that mean

They absorb dye very easily which is why they were called chromosomes as this makes them visible under a microscope but they can only be seen as individual threads when a cell is dividing

Chromosomes ?

Are long, thin, intertwined thread like structures made up of a strand of DNA wound around proteins

What is the wound around proteins called

Histones

If histones are attached to DNA what does it do

It helps it to coul up during cell division

In a body ( somatic ) cells chromosomes occur like what?

Homologous pairs

What are genes

Sections of DNA molecules that control hereditary characteristics

Who discovered the structure of DNA

Maurice wilkins and rosalind Franklin

Who also became interested in DNA

- Francis Crick


- James Watson

What did James Watson discover ?

Discovered spiral helical

Who won the Nobel prize for DNA

Watson, crick and wilkins

What is the shape of DNA

Is a long, twisted ladder, forming a stable, 3 dimensional double helix

What are nucleotides

The double stranded DNA molecules Is made up of releating units, building blocks linked to form long nucleic acids chains

Each nucleotide is made up of

- sugar molecules ( deoxyribose )


- phosphate molecule


- nitrogenous base

What is the nitrogenous base made up of

- adenine


- thymine


- guanine


- cytosine

The four bases are what

The foundation of the genetic code, instructing cells on how to synthesize enzymes and other proteins

How is the double helix made up

- the outer 2 strands of the ladder are formed by a chain of alternating sugar/ phosphate links.



- the rungs of the ladder are formed from pairs of bases linked by weak hydrogen bonds



- the nitrogenous base pairs are attached to the sugar molecules

What does adenine bond with?

Only bonds with thymine or uracil



A = T


A = U

What does Cytosine bond with

Bonds with guanine



C = G

There are 2 groups of nitrogenous bases

- purines


- pyrimidines

What are purines

They are made up of 2 rings of nitrogen, oxygen and hydrogen atoms.



Examples are guanine and adenine

Pyridmidines are what

Made up I'd one rings of similar atoms and are therefore much smaller that purines



Examples are thymine and cytosine and uracil

What is it known as when determining the order of the bases in a DNA chain

DNA sequencing

What determines the genetic code

The sequence of the four bases

How do organisms differ

The sequences in which the base pairs are strung together

What is the role of DNA molecules

- carry coded genetic information in each cell in the form of Gene's which provide a blueprint for an organisms growth and development by coding for a specific protein



- can replicate

What are exons

Protein coding regions of a DNA molecule

What are they interrupted by

Non coding regions called introns

Non coding regions are known to form

Functional RNA molecules

Replication

Is the process of making a new DNA molecule from an existing DNA molecule which is identical to the original molecule

What phase does replication take place

Interphase

Why is replication necessary

The dna needs to produce another molecule exactly the same as itself to ensure that the genetic code is passed on to each daughter cell formed during cell division.

How does replication take place ?

- the hydrogen bonds between the 2 strands break, allowing the strands to part



- free nucleotides in the cytoplasm bond to their matching , exposed base partners



- the 2 daughter DNA molecules each twist to form a double helix which then winds itself around the histones (proteins) forming a chromosome

What is the structure or RNA

- consists of a single strand


- the strand is much shorter


- the sugar is ribose


- it has 3 bases in common with DNA: adenine, cytosine, guanins but a base uracil replaces thymine

What is the function of RNA

RNA carries instructions from DNA in the nucleus to the ribosomes in the cytoplasm of a cell where it controls the synthesis of proteins from amino acids


What are cell chemical processes controlled by

Enzymes

What are the different types of rna

- messenger rna ( mRNA )


- transfer rna ( tRNA )


- ribosomal rna ( rRNA)

What is transcription

When mRNA is formed in the nucleus in the same way as DNAS replication takes places.

Transcription is the process whereby

DNA makes and codes mRNA

How does transcription take place

- the process starts when a small piece of DNA, a gene, unwinds and the two strands separate



- new nucleotides pair up with their complementary bases on one of the dna strands. This strand is called the template as it Carrie's the code



- the nucleotides join up to form a strand of mRNA. Therefore the dna transcribes its genetic code to the mRna



- note that a uracil base will pair with an adenine base



- a coveted strand of mrna breaks away from the dna. The dna then re-zips



- the relatively small mrna moves through the pores of the nuclear membrane and Carrie's the genetic code to the ribosomes which are the sites of protein synthesis

What is an amino acids

It is a long chain ( polymer) of small units

How many different amino acids are involved in protein synthesis

20

What determines what type of protein is made

The order in which amino acids are linked

The sequence of amino acids is determined by

Instructions from the genetic code

How is the genetic code carried

Carried as a sequence of code words which are transcribed to the mRna

What is a codon

When a codeword is made up of any three bases

How many codons are there

64

The three codons that did not code for an amino acid are called what

Stop codons

What does the order of codons determine

The sequence of amino acids which will determine which protein is made

What happens at the ribosome

The mrna Hinds to the ribosome at the start codon. The codons of the mrna act as a template that determines the order in which the amino acids are linked

Each trna has 3 bases at one end called

An anti codon

What do anti codons do

Pick up specific amino acids found in the cytoplasm and transfers it to a ribosome

Translation of rna into proteins process

- the ani codon bases link up to their complementary bases of the codon. As the code on the mrna is translated into a sequence of amino acids



- the trna molecule is released to carry more of its specific amino acid to the ribosome



- catalyzed by enzymes, the amino acids link together with peptide bonds to form polypeptide chain



- the polypeptide chains link together to form the final functional protein

What is translation

The process by which a specific protein is formed from a chain of amino acids due to the sequence of codons in the mrna which in turn was coded by the DNA

What is the role of rRNA

The rrna moves from the codon to codon along the mrna reading the code. Therefore plays an important role in the controlling the process of protein synthesis

Where is the genetic code stored

It is stored along the length of a dna strand as a sequence of the 4 bases

The nucleotides are arranged into how many groups

3

What does each codon do

It codes for a particular amino acid