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7 Cards in this Set
- Front
- Back
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Function of DNA Polymerase I
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Degrades RNA produced during DNA replication via 5'-->3' Endonuclease
Replaces with DNA |
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Function of Ligase
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Connects Okazaki fragments after replacement by DNA Polymerase I
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Function of Primase
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Create RNA primer in DNA replication to provide 3'OH from which replication can occur
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Function of Gyrase
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To unwind negatively supercoiled DNA
aka Topoisomerase II |
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Function of DNA Polymerase III
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Synthesize leading strand of DNA replication and proofread w/ 3'-->5' exonuclease activity.
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Function of Telomerase
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Reverse transcriptase activity to add nucleotides to the 3' end of the lagging strand during replication to prevent loss of genetic material.
Malignant cells usually have upregulated telomerase activity. |
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What happens when a ribsome encounters a stop codon on mRNA
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Binds releasing factor.
Ribosome disassembles and protein is released |
