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15 Cards in this Set
- Front
- Back
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The most common cause of spinal root disease is?
2 other less common causes are? |
Most common cause: compression
Less common: demyelination, infection |
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What is the hall mark of compressive spinal root disease?
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Pain in a myotomal pattern
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Other than hall mark of compressive spinal root disease, what are the other characteristic of this disease?
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1. focal and asymmetricl signs and symptoms
2. dermatomal pattern sensory loss 3. LMN sign |
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What can the pathology be classified concerning spinal cord disease?
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1. intrinsic
2. extrinsic |
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What are the characteristic of spinal cord disease?
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1. symmetrical UMN below lesion
2. LMN at the level 3. bowel, bladder, sexual problem |
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Given the mode of onset of spinal cord disease, we can form an initial DDX. Please make the list.
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Hyperacute : trauma
Acute: vascular Subacute: inflammation, demyelination, compressive Chronic: degenerative, metabolic, hereditary |
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How is multiple sclerosis be diagnosed?
What criteria can be used? |
2 attacks
Mc Donald criteria |
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Characteristics of multiple sclerosis
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1. immunological demyelination of CS
2. in young 3. relapsing and remitting course |
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Give 4 variants of MS
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1, benign MS
2. malignant MS 3. primary progressive 3. secondary progressive |
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Characteristic of primary progressive MS
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1. older
2. poorer prognosis 3. Less MRI brain lesiion 4. without clear relapsing-remitting course |
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Where does secondary progressive MS come from?
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Evolve from relapsing-remitting MS
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Characteristics of Asian MS
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1. optico-spinal form is more common
2. lesion more necrotic 3. MRI brain less demyelinative hyperintense lesion 4. Less associated with HLA-DR2 |
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Medicl Tx of MS
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1. pulse methyprednisolone x 3days, followed by prednisolone
2. Beta-interferon |
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What is the use of steroid in MS
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1. Immunomodulatory
2. Anti-inflammatory 3. Improve axonal conduction |
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Can steroid stop MS development?
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No
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