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19 Cards in this Set
- Front
- Back
Glycolysis
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-substrate level phosphorylation-
-first stage in glucose catabolism -does not require O2 -yields 2 pyruvate + 2ATP + 2NADH -occurs in the cytoplasm |
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Glucose + 2ADP + 2 INORGANIC PHOSPHATE + 2NAD+ ----> 2 PYRUVATE + 2ATP + 2NADH + 2H+ + H20
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net rxn for GLYCOLYSIS
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Glycolysis ---> fermenation in the ____ of O2
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absence
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Glycolysis ---> Kreb's cycle (TCA cycle) in the _____ of O2
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presence
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Fermentation
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-goal is to reduce pyruvate to ethanol or lactic acid in the absence of O2 in order to produce additional NAD+ to keep fueling glycolysis and produce additional 2ATP/glucose
-occurs in the cytoplasm |
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Net glucose of glycolysis + fermentation
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4 ATP / glucose molecule
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Alcohol fermentation occurs in
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in yeast and some bacteria
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Lactic acid fermentation occurs in
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fungi, bacteria, and human muscle cells
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Glycolysis ---> _______ ---> Kreb's cycle
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2 pyruvate + coenzyme A --> acetyl CoA + CO2
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kreb's cycle (citric acid cycle)
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-end goal is to reduce NAD+ and FAD to NADH and FADH2 for them to transport electrons to the electron transport chain
-also produces 2 ATP/turn of the cycle |
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Net rxn for the citric acid cycle (Kreb's cycle)
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2 ACETYL COA + 6NAD+ + 2FAD + 2GTP + 2INORGANIC PHOS + 4H20 ---> 4CO2 + 6NADH + 2FADH2 + 2ATP + 4H+ + 2COA
--occurs in the inner membrance of the mitochondria |
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Electron transport chain
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-main idea: oxidize Nadh + FADH2 to NAD+ and FAD+ to form ATP
-occurs in the inner mitochondrial membrame |
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Steps in the electron transport chain
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1. NADH enters at NADH dehydrogenase complex
2. FADH2 enters at cytochrome q 3. electrons are transferred from one cytochrome to the other via redox 4. electrons eventually reach O2, which is the final electron acceptor in the chain and forms H2O |
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As electrons in the transport chain they lose energy, which is harvested to produce _____
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ATP
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AS electrons are transported down the ETC, H+ are pumped out of the mitochondrial matrix across the _______ into the _______
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inner mitchondrial membrane, inter membrane space
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Electrochemical gradient formed by H+ pumped out, forces _____ back into the inner membrane and into the matrix
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H+
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H+ is pumped in/out thru ______ which uses that energy to phosphorylate ADP to _____
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ATP synthase channels, ATP
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Net ATP formed from glycolysis ---> ETC
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36 ATP / glucose
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Net ATP formed from glycolysis ---> fermentation
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4 ATP/ glucose
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