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19 Cards in this Set

  • Front
  • Back
Glycolysis
-substrate level phosphorylation-
-first stage in glucose catabolism
-does not require O2
-yields 2 pyruvate + 2ATP + 2NADH
-occurs in the cytoplasm
Glucose + 2ADP + 2 INORGANIC PHOSPHATE + 2NAD+ ----> 2 PYRUVATE + 2ATP + 2NADH + 2H+ + H20
net rxn for GLYCOLYSIS
Glycolysis ---> fermenation in the ____ of O2
absence
Glycolysis ---> Kreb's cycle (TCA cycle) in the _____ of O2
presence
Fermentation
-goal is to reduce pyruvate to ethanol or lactic acid in the absence of O2 in order to produce additional NAD+ to keep fueling glycolysis and produce additional 2ATP/glucose
-occurs in the cytoplasm
Net glucose of glycolysis + fermentation
4 ATP / glucose molecule
Alcohol fermentation occurs in
in yeast and some bacteria
Lactic acid fermentation occurs in
fungi, bacteria, and human muscle cells
Glycolysis ---> _______ ---> Kreb's cycle
2 pyruvate + coenzyme A --> acetyl CoA + CO2
kreb's cycle (citric acid cycle)
-end goal is to reduce NAD+ and FAD to NADH and FADH2 for them to transport electrons to the electron transport chain
-also produces 2 ATP/turn of the cycle
Net rxn for the citric acid cycle (Kreb's cycle)
2 ACETYL COA + 6NAD+ + 2FAD + 2GTP + 2INORGANIC PHOS + 4H20 ---> 4CO2 + 6NADH + 2FADH2 + 2ATP + 4H+ + 2COA
--occurs in the inner membrance of the mitochondria
Electron transport chain
-main idea: oxidize Nadh + FADH2 to NAD+ and FAD+ to form ATP
-occurs in the inner mitochondrial membrame
Steps in the electron transport chain
1. NADH enters at NADH dehydrogenase complex
2. FADH2 enters at cytochrome q
3. electrons are transferred from one cytochrome to the other via redox
4. electrons eventually reach O2, which is the final electron acceptor in the chain and forms H2O
As electrons in the transport chain they lose energy, which is harvested to produce _____
ATP
AS electrons are transported down the ETC, H+ are pumped out of the mitochondrial matrix across the _______ into the _______
inner mitchondrial membrane, inter membrane space
Electrochemical gradient formed by H+ pumped out, forces _____ back into the inner membrane and into the matrix
H+
H+ is pumped in/out thru ______ which uses that energy to phosphorylate ADP to _____
ATP synthase channels, ATP
Net ATP formed from glycolysis ---> ETC
36 ATP / glucose
Net ATP formed from glycolysis ---> fermentation
4 ATP/ glucose